Satyesh Kumar Sinha, PhD
Title Assistant Professor
Institution Charles R. Drew University of Medicine and Science
Department Internal Medicine
School College of Medicine
Address 1731 E. 120th Street, Hawkins Building


Telephone (323) 563-5876
Fax
Email
Overview
My area of interest involves inflammation in macro and micro-vascular complications, like atherosclerosis and diabetic kidney disease. Minority populations are at higher risk of developing these chronic diseases. Our goal is to strengthen our understanding in the area, which will further be helpful to design novel therapeutic approaches for inflammatory process of atherosclerosis and diabetic kidney disease.
Education & Training
Teaching
NIH Awarded Grants
Project TitleProject NumberFY
Publications
1. Sinha SK, Nicholas SB, Sung JH, Correa A, Rajavashisth TB, Norris KC, Lee JE. hs-CRP Is Associated With Incident Diabetic Nephropathy: Findings From the Jackson Heart Study. Diabetes Care. 2019 Nov; 42(11):2083-2089.
  View in: PubMed
 
2. Espinoza-Derout J, Hasan KM, Shao XM, Jordan MC, Sims C, Lee DL, Sinha S, Simmons Z, Mtume N, Liu Y, Roos KP, Sinha-Hikim AP, Friedman TC. Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H445-H459.
  View in: PubMed
 
3. Erbilgin A, Seldin MM, Wu X, Mehrabian M, Zhou Z, Qi H, Dabirian KS, Sevag Packard RR, Hsieh W, Bensinger SJ, Sinha S, Lusis AJ. Transcription Factor Zhx2 Deficiency Reduces Atherosclerosis and Promotes Macrophage Apoptosis in Mice. Arterioscler Thromb Vasc Biol. 2018 09; 38(9):2016-2027.
  View in: PubMed
 
4. Mishra V, Sinha SK, Rajavashisth TB. Role of macrophage colony-stimulating factor in the development of neointimal thickening following arterial injury. Cardiovasc Pathol. 2016 Jul-Aug; 25(4):284-292.
  View in: PubMed
 
5. Sharma C, Sadek B, Goyal SN, Sinha S, Kamal MA, Ojha S. Small Molecules from Nature Targeting G-Protein Coupled Cannabinoid Receptors: Potential Leads for Drug Discovery and Development. Evid Based Complement Alternat Med. 2015; 2015:238482.
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6. Qiao JH, Mishra V, Fishbein MC, Sinha SK, Rajavashisth TB. Multinucleated giant cells in atherosclerotic plaques of human carotid arteries: Identification of osteoclast-like cells and their specific proteins in artery wall. Exp Mol Pathol. 2015 Dec; 99(3):654-62.
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7. Sinha SK, Mishra V, Nagwani S, Rajavashisth TB. Effects of G-CSF on serum cholesterol and development of atherosclerotic plaque in apolipoprotein E-deficient mice. Int J Clin Exp Med. 2014; 7(8):1979-89.
  View in: PubMed
 
8. Sinha SK, Shaheen M, Rajavashisth TB, Pan D, Norris KC, Nicholas SB. Association of race/ethnicity, inflammation, and albuminuria in patients with diabetes and early chronic kidney disease. Diabetes Care. 2014 Apr; 37(4):1060-8.
  View in: PubMed
 
9. Sinha SK, Asotra K, Uzui H, Nagwani S, Mishra V, Rajavashisth TB. Nuclear localization of catalytically active MMP-2 in endothelial cells and neurons. Am J Transl Res. 2014; 6(2):155-62.
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10. Rajavashisth TB, Shaheen M, Norris KC, Pan D, Sinha SK, Ortega J, Friedman TC. Decreased prevalence of diabetes in marijuana users: cross-sectional data from the National Health and Nutrition Examination Survey (NHANES) III. BMJ Open. 2012; 2:e000494.
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11. Uzui H, Sinha SK, Rajavashisth TB. 17ß-estradiol inhibits oxidized low-density lipoprotein-induced increase in matrix metalloproteinase-9 expression in human macrophages. J Investig Med. 2011 Oct; 59(7):1104-8.
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12. Nicholas SB, Basgen JM, Sinha S. Using stereologic techniques for podocyte counting in the mouse: shifting the paradigm. Am J Nephrol. 2011; 33 Suppl 1:1-7.
  View in: PubMed
 
13. Chandramohan G, Durham N, Sinha S, Norris K, Vaziri ND. Role of gamma melanocyte-stimulating hormone-renal melanocortin 3 receptor system in blood pressure regulation in salt-resistant and salt-sensitive rats. Metabolism. 2009 Oct; 58(10):1424-9.
  View in: PubMed
 
14. Singh R, Bhasin S, Braga M, Artaza JN, Pervin S, Taylor WE, Krishnan V, Sinha SK, Rajavashisth TB, Jasuja R. Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways. Endocrinology. 2009 Mar; 150(3):1259-68.
  View in: PubMed
 
Funding Opportunities

Click terms below for current NIH/NSF funding opportunities.
  • Albuminuria


  • Diabetes Complications


  • Kidney Failure, Chronic


  • Continental Population Groups


  • Ethnic Groups


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Co-Authors  
Friedman, Theodore
Pan, Deyu
Rajavashisth, Tripathi
Shaheen, Magda
Sinha-Hikim, Amiya
See all (12) people
Physical Neighbors  
Basgen, John
Ferrini, Monica
Gonzalez-Cadavid, Nestor
Friedman, Theodore
Chaban, Victor


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