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Gregory Brent to Animals

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This is a "connection" page, showing publications Gregory Brent has written about Animals.
Gregory Brent
Connection Strength
3.384
Animals
  1. Thyroxine Treatment after Traumatic Brain Injury Suppresses Astrogliosis and Enhances Neuronal Recovery in Mice. Thyroid. 2025 09; 35(9):1083-1094.
    View in: PubMed
    Score: 0.165
  2. A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer. Clin Cancer Res. 2024 04 01; 30(7):1220-1222.
    View in: PubMed
    Score: 0.150
  3. A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 10; 33(10):1140-1149.
    View in: PubMed
    Score: 0.143
  4. Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105.
    View in: PubMed
    Score: 0.128
  5. Thyroid hormone receptor ? sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16).
    View in: PubMed
    Score: 0.125
  6. The Role of Thyroid Hormone in Neuronal Protection. Compr Physiol. 2021 06 01; 11(3):2075-2095.
    View in: PubMed
    Score: 0.123
  7. Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia by Reducing DNA Methylation and Apoptosis. Endocrinology. 2019 10 01; 160(10):2243-2256.
    View in: PubMed
    Score: 0.110
  8. Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury. Pharmacol Ther. 2018 06; 186:176-185.
    View in: PubMed
    Score: 0.098
  9. COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation. Thyroid. 2018 05; 28(5):667-678.
    View in: PubMed
    Score: 0.097
  10. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation. Methods Mol Biol. 2018; 1801:39-46.
    View in: PubMed
    Score: 0.097
  11. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation. Methods Mol Biol. 2018; 1801:47-59.
    View in: PubMed
    Score: 0.097
  12. Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging. Thyroid. 2017 10; 27(10):1316-1322.
    View in: PubMed
    Score: 0.095
  13. Thyroid hormone treatment activates protective pathways in both in?vivo and in?vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130.
    View in: PubMed
    Score: 0.093
  14. Thyroid Hormone Receptor a Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15.
    View in: PubMed
    Score: 0.083
  15. Thyroid hormone regulation of metabolism. Physiol Rev. 2014 Apr; 94(2):355-82.
    View in: PubMed
    Score: 0.075
  16. Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al. Thyroid. 2014 Jan; 24(1):1-2.
    View in: PubMed
    Score: 0.074
  17. Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9.
    View in: PubMed
    Score: 0.071
  18. Mechanisms of thyroid hormone action. J Clin Invest. 2012 Sep; 122(9):3035-43.
    View in: PubMed
    Score: 0.067
  19. Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508.
    View in: PubMed
    Score: 0.067
  20. The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70.
    View in: PubMed
    Score: 0.066
  21. Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300.
    View in: PubMed
    Score: 0.064
  22. Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression. Endocrinology. 2011 Mar; 152(3):1143-53.
    View in: PubMed
    Score: 0.060
  23. Environmental exposures and autoimmune thyroid disease. Thyroid. 2010 Jul; 20(7):755-61.
    View in: PubMed
    Score: 0.058
  24. Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288.
    View in: PubMed
    Score: 0.058
  25. Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab. 2010 Mar; 21(3):166-73.
    View in: PubMed
    Score: 0.056
  26. Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40.
    View in: PubMed
    Score: 0.055
  27. Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50.
    View in: PubMed
    Score: 0.053
  28. Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52.
    View in: PubMed
    Score: 0.051
  29. Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid. 2008 Jun; 18(6):593-5.
    View in: PubMed
    Score: 0.050
  30. A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation. Endocrinology. 2007 Mar; 148(3):1206-17.
    View in: PubMed
    Score: 0.045
  31. Hypothyroidism impairs skeletal muscle regeneration after injury by altering myogenic and nonmyogenic pathways. JCI Insight. 2026 Mar 23; 11(6).
    View in: PubMed
    Score: 0.043
  32. Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis. Endocrinology. 2005 Feb; 146(2):776-83.
    View in: PubMed
    Score: 0.039
  33. Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004 Jan 01; 64(1):415-22.
    View in: PubMed
    Score: 0.037
  34. A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem. 2003 Oct 03; 278(40):38913-20.
    View in: PubMed
    Score: 0.036
  35. The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2003 Mar; 78(1):119-26.
    View in: PubMed
    Score: 0.035
  36. A complex deoxyribonucleic acid response element in the rat Ca(2+)/calmodulin-dependent protein kinase IV gene 5'-flanking region mediates thyroid hormone induction and chicken ovalbumin upstream promoter transcription factor 1 repression. Mol Endocrinol. 2002 Nov; 16(11):2439-51.
    View in: PubMed
    Score: 0.034
  37. A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol. 2002 Oct; 16(10):2266-82.
    View in: PubMed
    Score: 0.034
  38. Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis. Thyroid. 2002 Aug; 12(8):663-71.
    View in: PubMed
    Score: 0.033
  39. A targeted thyroid hormone receptor alpha gene dominant-negative mutation (P398H) selectively impairs gene expression in differentiated embryonic stem cells. Endocrinology. 2002 Jul; 143(7):2664-72.
    View in: PubMed
    Score: 0.033
  40. Thyroid hormone stimulation of osteocalcin gene expression in ROS 17/2.8 cells is mediated by transcriptional and post-transcriptional mechanisms. J Endocrinol. 2001 Sep; 170(3):667-75.
    View in: PubMed
    Score: 0.031
  41. Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific. J Clin Invest. 2001 Jul; 108(1):97-105.
    View in: PubMed
    Score: 0.031
  42. Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021 02 25; 11(1):4601.
    View in: PubMed
    Score: 0.030
  43. Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8519-24.
    View in: PubMed
    Score: 0.029
  44. Tissue-specific actions of thyroid hormone: insights from animal models. Rev Endocr Metab Disord. 2000 Jan; 1(1-2):27-33.
    View in: PubMed
    Score: 0.028
  45. Thyroid hormone action: down novel paths. Focus on "thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells". Am J Physiol. 1999 05; 276(5):C1012-3.
    View in: PubMed
    Score: 0.027
  46. Retinoid-X receptor (RXR) differentially augments thyroid hormone response in cell lines as a function of the response element and endogenous RXR content. Endocrinology. 1995 Feb; 136(2):421-30.
    View in: PubMed
    Score: 0.020
  47. Thyroid hormone receptor-alpha inhibits retinoic acid-responsive gene expression and modulates retinoic acid-stimulated neural differentiation in mouse embryonic stem cells. Mol Endocrinol. 1994 Jun; 8(6):746-56.
    View in: PubMed
    Score: 0.019
  48. Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement. Endocrinology. 1994 Apr; 134(4):1888-96.
    View in: PubMed
    Score: 0.019
  49. Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients. Nephrol Dial Transplant. 2015 May; 30(5):724-37.
    View in: PubMed
    Score: 0.019
  50. Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors. Mol Endocrinol. 1992 Oct; 6(10):1527-37.
    View in: PubMed
    Score: 0.017
  51. Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements. Mol Endocrinol. 1992 Apr; 6(4):502-14.
    View in: PubMed
    Score: 0.016
  52. Oligomeric binding of T3 receptor is required for maximal T3 response. J Biol Chem. 1991 Oct 15; 266(29):19636-44.
    View in: PubMed
    Score: 0.016
  53. Effects of varying the position of thyroid hormone response elements within the rat growth hormone promoter: implications for positive and negative regulation by 3,5,3'-triiodothyronine. Mol Endocrinol. 1991 Apr; 5(4):542-8.
    View in: PubMed
    Score: 0.015
  54. Thyroid hormone regulation of gene expression. Annu Rev Physiol. 1991; 53:17-35.
    View in: PubMed
    Score: 0.015
  55. Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor. New Biol. 1989 Dec; 1(3):329-36.
    View in: PubMed
    Score: 0.014
  56. Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol Endocrinol. 1989 Dec; 3(12):1996-2004.
    View in: PubMed
    Score: 0.014
  57. Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor. J Biol Chem. 1989 Jan 05; 264(1):178-82.
    View in: PubMed
    Score: 0.013
  58. Multihormonal regulation of the human, rat, and bovine growth hormone promoters: differential effects of 3',5'-cyclic adenosine monophosphate, thyroid hormone, and glucocorticoids. Mol Endocrinol. 1988 Sep; 2(9):792-8.
    View in: PubMed
    Score: 0.013
  59. Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006 Dec; 16(12):1207-13.
    View in: PubMed
    Score: 0.011
  60. Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45.
    View in: PubMed
    Score: 0.010
  61. Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements. J Mol Endocrinol. 2004 Aug; 33(1):21-33.
    View in: PubMed
    Score: 0.010
  62. Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1135-41.
    View in: PubMed
    Score: 0.009
  63. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72.
    View in: PubMed
    Score: 0.009
  64. A GC box in the human sodium iodide symporter gene promoter is essential for full activity. Thyroid. 2002 Feb; 12(2):107-14.
    View in: PubMed
    Score: 0.008
  65. Regulation of prohormone convertase 1 (PC1) by thyroid hormone. Am J Physiol Endocrinol Metab. 2001 Jan; 280(1):E160-70.
    View in: PubMed
    Score: 0.007
  66. Interactions between the prohormone convertase 2 promoter and the thyroid hormone receptor. Endocrinology. 2000 Sep; 141(9):3256-66.
    View in: PubMed
    Score: 0.007
  67. Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation. Nat Genet. 1997 Oct; 17(2):179-81.
    View in: PubMed
    Score: 0.006
  68. Characterization of the promoter of the rat sarcoplasmic endoplasmic reticulum Ca2+-ATPase 1 gene and analysis of thyroid hormone responsiveness. J Biol Chem. 1996 Dec 13; 271(50):32048-56.
    View in: PubMed
    Score: 0.006
  69. Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor. Endocrinology. 1996 Jul; 137(7):2833-41.
    View in: PubMed
    Score: 0.005
  70. Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific. Mol Endocrinol. 1993 Oct; 7(10):1319-30.
    View in: PubMed
    Score: 0.005
  71. Direct repeats. Nature. 1990 Jun 14; 345(6276):584.
    View in: PubMed
    Score: 0.004
  72. Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature. 1989 Feb 16; 337(6208):659-61.
    View in: PubMed
    Score: 0.003
  73. Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5031-5.
    View in: PubMed
    Score: 0.003
  74. Thyroid hormone receptor binds to a site in the rat growth hormone promoter required for induction by thyroid hormone. Proc Natl Acad Sci U S A. 1987 Aug; 84(16):5670-4.
    View in: PubMed
    Score: 0.003
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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.