Regulation of the Sodium/Iodide Symporter in Breast
ANIMAL AND CELLULAR MODELS OF THYROID HORMONE RESISTANCE
Thyroid Hormone Receptor Isoform-Specific Actions
Kogai T, Liu YY, Mody K, Shamsian DV, Brent GA
Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300.
Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells.
Williams GR, Harney JW, Moore DD, Larsen PR, Brent GA
Molecular endocrinology (Baltimore, Md.)
Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors. Mol Endocrinol. 1992 Oct; 6(10):1527-37.
Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors.
Specificity of nuclear hormone receptor action: who conducts the orchestra? J Endocrinol. 1992 Nov; 135(2):191-4.
Specificity of nuclear hormone receptor action: who conducts the orchestra?
Brent GA, Williams GR, Harney JW, Forman BM, Samuels HH, Moore DD, Larsen PR
Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements. Mol Endocrinol. 1992 Apr; 6(4):502-14.
Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements.
Koenig RJ, Lazar MA, Hodin RA, Brent GA, Larsen PR, Chin WW, Moore DD
Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature. 1989 Feb 16; 337(6208):659-61.
Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing.
The Journal of clinical endocrinology and metabolism
Adrenocorticotropin stimulation of aldosterone: prolonged continuous versus pulsatile infusion. J Clin Endocrinol Metab. 1989 Nov; 69(5):1028-32.
Adrenocorticotropin stimulation of aldosterone: prolonged continuous versus pulsatile infusion.
Brent GA, Dunn MK, Harney JW, Gulick T, Larsen PR, Moore DD
Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor. New Biol. 1989 Dec; 1(3):329-36.
Thyroid hormone aporeceptor represses T3-inducible promoters and blocks activity of the retinoic acid receptor.
Brent GA, Harney JW, Chen Y, Warne RL, Moore DD, Larsen PR
Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element. Mol Endocrinol. 1989 Dec; 3(12):1996-2004.
Mutations of the rat growth hormone promoter which increase and decrease response to thyroid hormone define a consensus thyroid hormone response element.
Brent GA, Harney JW, Moore DD, Larsen PR
Multihormonal regulation of the human, rat, and bovine growth hormone promoters: differential effects of 3',5'-cyclic adenosine monophosphate, thyroid hormone, and glucocorticoids. Mol Endocrinol. 1988 Sep; 2(9):792-8.
Multihormonal regulation of the human, rat, and bovine growth hormone promoters: differential effects of 3',5'-cyclic adenosine monophosphate, thyroid hormone, and glucocorticoids.
Koenig RJ, Warne RL, Brent GA, Harney JW, Larsen PR, Moore DD
Proceedings of the National Academy of Sciences of the United States of America
Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5031-5.
Isolation of a cDNA clone encoding a biologically active thyroid hormone receptor.
Brent GA, Larsen PR, Harney JW, Koenig RJ, Moore DD
Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor. J Biol Chem. 1989 Jan 05; 264(1):178-82.
Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected beta type thyroid hormone receptor.
Reversible alteration of red cell lithium-sodium countertransport in patients with thyroid disease. J Clin Endocrinol Metab. 1989 Feb; 68(2):322-8.
Reversible alteration of red cell lithium-sodium countertransport in patients with thyroid disease.
Thyroxine therapy in patients with severe nonthyroidal illnesses and low serum thyroxine concentration. J Clin Endocrinol Metab. 1986 Jul; 63(1):1-8.
Thyroxine therapy in patients with severe nonthyroidal illnesses and low serum thyroxine concentration.
Brent GA, LeBoff MS, Seely EW, Conlin PR, Brown EM
Relationship between the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans. J Clin Endocrinol Metab. 1988 Nov; 67(5):944-50.
Relationship between the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans.
Brent GA, Hershman JM, Reed AW, Sastre A, Lieberman J
Serum angiotensin-converting enzyme in severe nonthyroidal illnesses associated with low serum thyroxine concentration. Ann Intern Med. 1984 May; 100(5):680-3.
Serum angiotensin-converting enzyme in severe nonthyroidal illnesses associated with low serum thyroxine concentration.
Thyroid : official journal of the American Thyroid Association
Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis. Thyroid. 1994; 4(1):129-33.
Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis.
Mandel SJ, Brent GA, Weinblatt M, Larsen PR
Prospective studies of thyroid function in patients receiving gold therapy. Thyroid. 1995 Apr; 5(2):113-6.
Prospective studies of thyroid function in patients receiving gold therapy.
Zavacki AM, Harney JW, Brent GA, Larsen PR
Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific. Mol Endocrinol. 1993 Oct; 7(10):1319-30.
Dominant negative inhibition by mutant thyroid hormone receptors is thyroid hormone response element and receptor isoform specific.
Levothyroxine therapy in patients with thyroid disease. Ann Intern Med. 1993 Sep 15; 119(6):492-502.
Levothyroxine therapy in patients with thyroid disease.
Maternal thyroid function: interpretation of thyroid function tests in pregnancy. Clin Obstet Gynecol. 1997 Mar; 40(1):3-15.
Maternal thyroid function: interpretation of thyroid function tests in pregnancy.
Lu W, Peissel B, Babakhanlou H, Pavlova A, Geng L, Fan X, Larson C, Brent G, Zhou J
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation. Nat Genet. 1997 Oct; 17(2):179-81.
Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation.
Thyroid hormone action: down novel paths. Focus on "thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells". Am J Physiol. 1999 05; 276(5):C1012-3.
Thyroid hormone action: down novel paths. Focus on "thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells".
Maternal hypothyroidism: recognition and management. Thyroid. 1999 Jul; 9(7):661-5.
Maternal hypothyroidism: recognition and management.
Kogai T, Schultz JJ, Johnson LS, Huang M, Brent GA
Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8519-24.
Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line.
Kogai T, Curcio F, Hyman S, Cornford EM, Brent GA, Hershman JM
Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression. J Endocrinol. 2000 Oct; 167(1):125-35.
Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression.
Reviews in endocrine & metabolic disorders
Tissue-specific actions of thyroid hormone: insights from animal models. Rev Endocr Metab Disord. 2000 Jan; 1(1-2):27-33.
Tissue-specific actions of thyroid hormone: insights from animal models.
An J, Lichtenstein AK, Brent G, Rettig MB
The Kaposi sarcoma-associated herpesvirus (KSHV) induces cellular interleukin 6 expression: role of the KSHV latency-associated nuclear antigen and the AP1 response element. Blood. 2002 Jan 15; 99(2):649-54.
The Kaposi sarcoma-associated herpesvirus (KSHV) induces cellular interleukin 6 expression: role of the KSHV latency-associated nuclear antigen and the AP1 response element.
Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9.
Cancer: Novel target to enhance radioiodine uptake in thyroid cancer.
Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al. Thyroid. 2014 Jan; 24(1):1-2.
Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al.
Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age. Evid Based Nurs. 2014 Jul; 17(3):86.
Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age.
Refetoff S, Bassett JH, Beck-Peccoz P, Bernal J, Brent G, Chatterjee K, De Groot LJ, Dumitrescu AM, Jameson JL, Kopp PA, Murata Y, Persani L, Samarut J, Weiss RE, Williams GR, Yen PM
Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab. 2014 Mar; 99(3):768-70.
Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism.
Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Eur Thyroid J. 2014 Mar; 3(1):7-9.
Labadzhyan A, Brent GA, Hershman JM, Leung AM
Journal of clinical & translational endocrinology
Thyrotoxicosis of Pregnancy. J Clin Transl Endocrinol. 2014 Dec 01; 1(4):140-144.
Perchlorate exposure in pregnancy and cognitive outcomes in children: it's not your mother's thyroid. J Clin Endocrinol Metab. 2014 Nov; 99(11):4066-8.
Perchlorate exposure in pregnancy and cognitive outcomes in children: it's not your mother's thyroid.
Lee SY, Rhee CM, Leung AM, Braverman LE, Brent GA, Pearce EN
A review: Radiographic iodinated contrast media-induced thyroid dysfunction. J Clin Endocrinol Metab. 2015 Feb; 100(2):376-83.
A review: Radiographic iodinated contrast media-induced thyroid dysfunction.
Teng X, Jin T, Brent GA, Wu A, Teng W, Shan Z
A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T). J Clin Endocrinol Metab. 2015 Jul; 100(7):2511-4.
A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T).
Milanesi A, Lee JW, Kim NH, Liu YY, Yang A, Sedrakyan S, Kahng A, Cervantes V, Tripuraneni N, Cheng SY, Perin L, Brent GA
Thyroid Hormone Receptor a Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15.
Thyroid Hormone Receptor a Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury.
Taki K, Kogai T, Kanamoto Y, Hershman JM, Brent GA
A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol. 2002 Oct; 16(10):2266-82.
A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells.
A complex deoxyribonucleic acid response element in the rat Ca(2+)/calmodulin-dependent protein kinase IV gene 5'-flanking region mediates thyroid hormone induction and chicken ovalbumin upstream promoter transcription factor 1 repression. Mol Endocrinol. 2002 Nov; 16(11):2439-51.
A complex deoxyribonucleic acid response element in the rat Ca(2+)/calmodulin-dependent protein kinase IV gene 5'-flanking region mediates thyroid hormone induction and chicken ovalbumin upstream promoter transcription factor 1 repression.
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2003 Mar; 78(1):119-26.
The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells.
Zhang L, Sharma S, Zhu LX, Kogai T, Hershman JM, Brent GA, Dubinett SM, Huang M
Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72.
Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells.
Lafranchi SH, Snyder DB, Sesser DE, Skeels MR, Singh N, Brent GA, Nelson JC
Follow-up of newborns with elevated screening T4 concentrations. J Pediatr. 2003 Sep; 143(3):296-301.
Follow-up of newborns with elevated screening T4 concentrations.
Xu J, Moatamed F, Caldwell JS, Walker JR, Kraiem Z, Taki K, Brent GA, Hershman JM
Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab. 2003 Oct; 88(10):4990-6.
Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells.
Kogai T, Kanamoto Y, Che LH, Taki K, Moatamed F, Schultz JJ, Brent GA
Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004 Jan 01; 64(1):415-22.
Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models.
Kogai T, Kanamoto Y, Li AI, Che LH, Ohashi E, Taki K, Chandraratna RA, Saito T, Brent GA
Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology. 2005 Jul; 146(7):3059-69.
Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells.
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Rapid progression from subclinical to symptomatic overt hypothyroidism. Endocr Pract. 2005 Mar-Apr; 11(2):115-9.
Rapid progression from subclinical to symptomatic overt hypothyroidism.
Anaplastic thyroid carcinoma with thyrotoxicosis and hypoparathyroidism. Endocr Pract. 2005 Jul-Aug; 11(4):281-4.
Anaplastic thyroid carcinoma with thyrotoxicosis and hypoparathyroidism.
Liu YY, Heymann RS, Moatamed F, Schultz JJ, Sobel D, Brent GA
A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation. Endocrinology. 2007 Mar; 148(3):1206-17.
A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation.
O'Barr SA, Oh JS, Ma C, Brent GA, Schultz JJ
Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006 Dec; 16(12):1207-13.
Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models.
Diagnosing thyroid dysfunction in pregnant women: Is case finding enough? J Clin Endocrinol Metab. 2007 Jan; 92(1):39-41.
Diagnosing thyroid dysfunction in pregnant women: Is case finding enough?
Thyroid health and the environment. Thyroid. 2007 Sep; 17(9):807-9.
Clinical practice. Graves' disease. N Engl J Med. 2008 Jun 12; 358(24):2594-605.
Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid. 2008 Jun; 18(6):593-5.
Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression.
Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, Grobman WA, Laurberg P, Lazarus JH, Mandel SJ, Peeters RP, Sullivan S
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. 2017 03; 27(3):315-389.
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum.
Li J, Donangelo I, Abe K, Scremin O, Ke S, Li F, Milanesi A, Liu YY, Brent GA
Thyroid hormone treatment activates protective pathways in both in?vivo and in?vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130.
Thyroid hormone treatment activates protective pathways in both in?vivo and in?vitro models of neuronal injury.
Beam Me In: Thyroid Hormone Analog Targets Alternative Transporter in Mouse Model of X-Linked Adrenoleukodystrophy Endocrinology. 2017 04 29; 158(5):1116-1119.
Beam Me In: Thyroid Hormone Analog Targets Alternative Transporter in Mouse Model of X-Linked Adrenoleukodystrophy
Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury. Pharmacol Ther. 2018 06; 186:176-185.
Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury.
Methods in molecular biology (Clifton, N.J.)
Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation. Methods Mol Biol. 2018; 1801:39-46.
Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation.
Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation. Methods Mol Biol. 2018; 1801:47-59.
Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation.
Gourdain PA, Brent G, Greenly JB, Hammer DA, Shapovalov RV
The generation of mega-gauss fields on the Cornell beam research accelerator. Rev Sci Instrum. 2018 Sep; 89(9):095102.
The generation of mega-gauss fields on the Cornell beam research accelerator.
Liu YY, Nakatani T, Kogai T, Mody K, Brent GA
Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression. Endocrinology. 2011 Mar; 152(3):1143-53.
Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression.
Publication of industry-sponsored medical research: guidelines from the Consortium of Laboratory Medicine Journal Editors. Thyroid. 2011 Jul; 21(7):693.
Publication of industry-sponsored medical research: guidelines from the Consortium of Laboratory Medicine Journal Editors.
Current opinion in endocrinology, diabetes, and obesity
Management of hypothyroidism in pregnancy. Curr Opin Endocrinol Diabetes Obes. 2011 Oct; 18(5):304-9.
Management of hypothyroidism in pregnancy.
The debate over thyroid-function screening in pregnancy. N Engl J Med. 2012 Feb 09; 366(6):562-3.
The debate over thyroid-function screening in pregnancy.
The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70.
The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics.
Liu YY, Kogai T, Schultz JJ, Mody K, Brent GA
Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508.
Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation.
Mechanisms of thyroid hormone action. J Clin Invest. 2012 Sep; 122(9):3035-43.
Li J, Abe K, Milanesi A, Liu YY, Brent GA
Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia by Reducing DNA Methylation and Apoptosis. Endocrinology. 2019 10 01; 160(10):2243-2256.
Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia by Reducing DNA Methylation and Apoptosis.
Inoue K, Ritz B, Brent GA, Ebrahimi R, Rhee CM, Leung AM
Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. JAMA Netw Open. 2020 02 05; 3(2):e1920745.
Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality.
Aguiari P, Liu YY, Petrosyan A, Cheng SY, Brent GA, Perin L, Milanesi A
Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021 02 25; 11(1):4601.
Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha.
The Role of Thyroid Hormone in Neuronal Protection. Compr Physiol. 2021 06 01; 11(3):2075-2095.
The Role of Thyroid Hormone in Neuronal Protection.
Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Thyroid. 2014 Mar; 24(3):407-9.
Thyroid hormone regulation of metabolism. Physiol Rev. 2014 Apr; 94(2):355-82.
Thyroid hormone regulation of metabolism.
Liu YY, Ayers S, Milanesi A, Teng X, Rabi S, Akiba Y, Brent GA
Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015 Mar 20; 290(12):7402-15.
Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation.
Leung AM, Korevaar TI, Peeters RP, Zoeller RT, K?hrle J, Duntas LH, Brent GA, Demeneix BA
Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action. Thyroid. 2016 Apr; 26(4):479-80.
Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action.
Liu YY, Jiang J, Ke S, Milanesi A, Abe K, Gastelum G, Li J, Brent GA
Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105.
Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores.
Chou R, Dana T, Brent GA, Goldner W, Haymart M, Leung AM, Ringel MD, Sosa JA
Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review. Thyroid. 2022 06; 32(6):613-639.
Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review.
Approach to the Patient With a Suppressed TSH. J Clin Endocrinol Metab. 2023 01 17; 108(2):472-482.
Approach to the Patient With a Suppressed TSH.
Thyroid Hormone-mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury. J Endocr Soc. 2022 Oct 11; 6(11):bvac139.
Thyroid Hormone-mediated Histone Modification Protects Cortical Neurons From the Toxic Effects of Hypoxic Injury.
Milanesi A, Lee JW, Yang A, Liu YY, Sedrakyan S, Cheng SY, Perin L, Brent GA
Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging. Thyroid. 2017 10; 27(10):1316-1322.
Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging.
COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation. Thyroid. 2018 05; 28(5):667-678.
COUP-TF1 Modulates Thyroid Hormone Action in an Embryonic Stem-Cell Model of Cortical Pyramidal Neuronal Differentiation.
Journal of the American Geriatrics Society
Older Adults with Cognitive Impairment Have Sex: More Evidence Against the Medical Myth of Sexless Aging. J Am Geriatr Soc. 2018 10; 66(10):1870-1871.
Older Adults with Cognitive Impairment Have Sex: More Evidence Against the Medical Myth of Sexless Aging.
Clinical cancer research : an official journal of the American Association for Cancer Research
A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer. Clin Cancer Res. 2024 04 01; 30(7):1220-1222.
A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer.
Weighing in on Thyroid Signaling in the Hypothalamus: Mechanisms and Interface with Metabolic Regulators. Thyroid. 2024 02; 34(2):141-143.
Weighing in on Thyroid Signaling in the Hypothalamus: Mechanisms and Interface with Metabolic Regulators.
Ringel MD, Sosa JA, Baloch Z, Bischoff L, Bloom G, Brent GA, Brock PL, Chou R, Flavell RR, Goldner W, Grubbs EG, Haymart M, Larson SM, Leung AM, Osborne JR, Ridge JA, Robinson B, Steward DL, Tufano RP, Wirth LJ
2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer. Thyroid. 2025 08; 35(8):841-985.
2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer.
Liu YY, Chen W, Aguiari P, Abe K, Milanesi A, Brent GA
Thyroxine Treatment after Traumatic Brain Injury Suppresses Astrogliosis and Enhances Neuronal Recovery in Mice. Thyroid. 2025 09; 35(9):1083-1094.
Thyroxine Treatment after Traumatic Brain Injury Suppresses Astrogliosis and Enhances Neuronal Recovery in Mice.
Wang SY, Stofer R, Wang H, Brent GA, Shi L, Cai Y, Roosan M, Moin T
Bridging Efficacy and Adherence in Glucagon-Like Peptide-1 Receptor Agonist Therapy: The Emerging Role of Oral Agents. Diabetes Metab J. 2025 Nov; 49(6):1331-1333.
Bridging Efficacy and Adherence in Glucagon-Like Peptide-1 Receptor Agonist Therapy: The Emerging Role of Oral Agents.
Not So Fast: Incomplete Assumptions of Adverse Thyroid Effects from PFAS Exposure. Environ Sci Technol. 2025 Dec 16; 59(49):26313-26315.
Not So Fast: Incomplete Assumptions of Adverse Thyroid Effects from PFAS Exposure.
Aguiari P, Villani V, Liu YY, Carraro G, Brent GA, Perin L, Milanesi A
Hypothyroidism impairs skeletal muscle regeneration after injury by altering myogenic and nonmyogenic pathways. JCI Insight. 2026 Mar 23; 11(6).
Hypothyroidism impairs skeletal muscle regeneration after injury by altering myogenic and nonmyogenic pathways.
Leung AM, Brent GA, Larson SM, Osborne JR, Flavell RR, Ringel MD, Sosa JA
Counseling Female Thyroid Cancer Patients on Radioactive Iodine and Fertility. Thyroid. 2026 May; 36(5):547-548.
Counseling Female Thyroid Cancer Patients on Radioactive Iodine and Fertility.
Williams GR, Harney JW, Forman BM, Samuels HH, Brent GA
Oligomeric binding of T3 receptor is required for maximal T3 response. J Biol Chem. 1991 Oct 15; 266(29):19636-44.
Oligomeric binding of T3 receptor is required for maximal T3 response.
Effects of varying the position of thyroid hormone response elements within the rat growth hormone promoter: implications for positive and negative regulation by 3,5,3'-triiodothyronine. Mol Endocrinol. 1991 Apr; 5(4):542-8.
Effects of varying the position of thyroid hormone response elements within the rat growth hormone promoter: implications for positive and negative regulation by 3,5,3'-triiodothyronine.
Thyroid hormone regulation of gene expression. Annu Rev Physiol. 1991; 53:17-35.
Thyroid hormone regulation of gene expression.
Koenig RJ, Brent GA, Larsen PR, Moore DD
Mandel SJ, Larsen PR, Seely EW, Brent GA
Increased need for thyroxine during pregnancy in women with primary hypothyroidism. N Engl J Med. 1990 Jul 12; 323(2):91-6.
Increased need for thyroxine during pregnancy in women with primary hypothyroidism.
Koenig RJ, Brent GA, Warne RL, Larsen PR, Moore DD
Thyroid hormone receptor binds to a site in the rat growth hormone promoter required for induction by thyroid hormone. Proc Natl Acad Sci U S A. 1987 Aug; 84(16):5670-4.
Thyroid hormone receptor binds to a site in the rat growth hormone promoter required for induction by thyroid hormone.
Patients with severe nonthyroidal illness and serum thyrotropin concentrations in the hypothyroid range. Am J Med. 1986 Sep; 81(3):463-6.
Patients with severe nonthyroidal illness and serum thyrotropin concentrations in the hypothyroid range.
Retinoid-X receptor (RXR) differentially augments thyroid hormone response in cell lines as a function of the response element and endogenous RXR content. Endocrinology. 1995 Feb; 136(2):421-30.
Retinoid-X receptor (RXR) differentially augments thyroid hormone response in cell lines as a function of the response element and endogenous RXR content.
Lee LR, Mortensen RM, Larson CA, Brent GA
Thyroid hormone receptor-alpha inhibits retinoic acid-responsive gene expression and modulates retinoic acid-stimulated neural differentiation in mouse embryonic stem cells. Mol Endocrinol. 1994 Jun; 8(6):746-56.
Thyroid hormone receptor-alpha inhibits retinoic acid-responsive gene expression and modulates retinoic acid-stimulated neural differentiation in mouse embryonic stem cells.
The molecular basis of thyroid hormone action. N Engl J Med. 1994 Sep 29; 331(13):847-53.
The molecular basis of thyroid hormone action.
Williams GR, Zavacki AM, Harney JW, Brent GA
Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement. Endocrinology. 1994 Apr; 134(4):1888-96.
Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement.
Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor. Endocrinology. 1996 Jul; 137(7):2833-41.
Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor.
Simonides WS, Brent GA, Thelen MH, van der Linden CG, Larsen PR, van Hardeveld C
Characterization of the promoter of the rat sarcoplasmic endoplasmic reticulum Ca2+-ATPase 1 gene and analysis of thyroid hormone responsiveness. J Biol Chem. 1996 Dec 13; 271(50):32048-56.
Characterization of the promoter of the rat sarcoplasmic endoplasmic reticulum Ca2+-ATPase 1 gene and analysis of thyroid hormone responsiveness.
Endocrinology and metabolism clinics of North America
Mechanisms of thyroid hormone action. Implications for the clinical manifestation of thyrotoxicosis. Endocrinol Metab Clin North Am. 1998 Mar; 27(1):1-23.
Mechanisms of thyroid hormone action. Implications for the clinical manifestation of thyrotoxicosis.
Ke S, Liu YY, Karthikraj R, Kannan K, Jiang J, Abe K, Milanesi A, Brent GA
Thyroid hormone receptor ? sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16).
Thyroid hormone receptor ? sumoylation is required for thyrotropin regulation and thyroid hormone production.
Ribeiro MO, Carvalho SD, Schultz JJ, Chiellini G, Scanlan TS, Bianco AC, Brent GA
Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific. J Clin Invest. 2001 Jul; 108(1):97-105.
Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific.
Kogai T, Hershman JM, Motomura K, Endo T, Onaya T, Brent GA
Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells. Endocrinology. 2001 Aug; 142(8):3369-79.
Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells.
Gouveia CH, Schultz JJ, Bianco AC, Brent GA
Thyroid hormone stimulation of osteocalcin gene expression in ROS 17/2.8 cells is mediated by transcriptional and post-transcriptional mechanisms. J Endocrinol. 2001 Sep; 170(3):667-75.
Thyroid hormone stimulation of osteocalcin gene expression in ROS 17/2.8 cells is mediated by transcriptional and post-transcriptional mechanisms.
Huang M, Batra RK, Kogai T, Lin YQ, Hershman JM, Lichtenstein A, Sharma S, Zhu LX, Brent GA, Dubinett SM
Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer. Cancer Gene Ther. 2001 Aug; 8(8):612-8.
Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer.
A GC box in the human sodium iodide symporter gene promoter is essential for full activity. Thyroid. 2002 Feb; 12(2):107-14.
A GC box in the human sodium iodide symporter gene promoter is essential for full activity.
Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients. Endocrinol Metab Clin North Am. 2002 Mar; 31(1):159-72.
Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients.
A targeted thyroid hormone receptor alpha gene dominant-negative mutation (P398H) selectively impairs gene expression in differentiated embryonic stem cells. Endocrinology. 2002 Jul; 143(7):2664-72.
A targeted thyroid hormone receptor alpha gene dominant-negative mutation (P398H) selectively impairs gene expression in differentiated embryonic stem cells.
Gouveia CH, Schultz JJ, Jackson DJ, Williams GR, Brent GA
Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis. Thyroid. 2002 Aug; 12(8):663-71.
Thyroid hormone gene targets in ROS 17/2.8 osteoblast-like cells identified by differential display analysis.
A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem. 2003 Oct 03; 278(40):38913-20.
A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice.
Freitas FR, Moriscot AS, Jorgetti V, Soares AG, Passarelli M, Scanlan TS, Brent GA, Bianco AC, Gouveia CH
American journal of physiology. Endocrinology and metabolism
Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1135-41.
Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1.
Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis. Endocrinology. 2005 Feb; 146(2):776-83.
Thyroid hormone-dependent gene expression in differentiated embryonic stem cells and embryonal carcinoma cells: identification of novel thyroid hormone target genes by deoxyribonucleic acid microarray analysis.
Introduction. The impact of maternal thyroid diseases on the developing fetus: implications for diagnosis, treatment, and screening. Summary of proceedings, workshop organization, program, and participants. Thyroid. 2005 Jan; 15(1):36-40.
Introduction. The impact of maternal thyroid diseases on the developing fetus: implications for diagnosis, treatment, and screening. Summary of proceedings, workshop organization, program, and participants.
Smallridge RC, Glinoer D, Hollowell JG, Brent G
Thyroid function inside and outside of pregnancy: what do we know and what don't we know? Thyroid. 2005 Jan; 15(1):54-9.
Thyroid function inside and outside of pregnancy: what do we know and what don't we know?
Resistance to thyroid hormone in Hashimoto's thyroiditis. N Engl J Med. 2005 Feb 03; 352(5):517-8.
Resistance to thyroid hormone in Hashimoto's thyroiditis.
Zhang L, Sharma S, Hershman JM, Brent GA, Dubinett SM, Huang M
Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation. Cancer Gene Ther. 2006 Jan 01; 13(1):74-81.
Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation.
Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. Endocr Relat Cancer. 2006 Sep; 13(3):797-826.
Enhancement of sodium/iodide symporter expression in thyroid and breast cancer.
A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 10; 33(10):1140-1149.
A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action.
Pregnancy-Does Promotion of Growth Extend to Thyroid Cancer? J Clin Endocrinol Metab. 2024 Jun 17; 109(7):e1552-e1553.
Pregnancy-Does Promotion of Growth Extend to Thyroid Cancer?
Phosphate Binder Impairs Levothyroxine Absorption in a Hypothyroid Patient With End-Stage Renal Disease. Cureus. 2024 Oct; 16(10):e71551.
Phosphate Binder Impairs Levothyroxine Absorption in a Hypothyroid Patient With End-Stage Renal Disease.
Dillon CF, Weisman MH, Leung AM, Brent GA, Miller FW
Autoimmune Thyroid Disease in the United States: Population Prevalence, Diagnosis Rates, and Trends. J Endocr Soc. 2025 Oct; 9(10):bvaf120.
Autoimmune Thyroid Disease in the United States: Population Prevalence, Diagnosis Rates, and Trends.
Kogai T, Ohashi E, Jacobs MS, Sajid-Crockett S, Fisher ML, Kanamoto Y, Brent GA
Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways. J Clin Endocrinol Metab. 2008 May; 93(5):1884-92.
Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways.
Trends in endocrinology and metabolism: TEM
Thyroid hormone receptor gene knockouts. Trends Endocrinol Metab. 1998 Apr; 9(3):103-12.
Thyroid hormone receptor gene knockouts.
Kogai T, Sajid-Crockett S, Newmarch LS, Liu YY, Brent GA
Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52.
Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells.
Ohashi E, Kogai T, Kagechika H, Brent GA
Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50.
Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells.
Ribeiro MO, Bianco SD, Kaneshige M, Schultz JJ, Cheng SY, Bianco AC, Brent GA
Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40.
Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis.
Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab. 2010 Mar; 21(3):166-73.
Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation.
Kogai T, Liu YY, Richter LL, Mody K, Kagechika H, Brent GA
Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288.
Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8).
Environmental exposures and autoimmune thyroid disease. Thyroid. 2010 Jul; 20(7):755-61.
Environmental exposures and autoimmune thyroid disease.
The impact of perchlorate exposure in early pregnancy: is it safe to drink the water? J Clin Endocrinol Metab. 2010 Jul; 95(7):3154-7.
The impact of perchlorate exposure in early pregnancy: is it safe to drink the water?
Rhee CM, Nguyen DV, Moradi H, Brunelli SM, Dukkipati R, Jing J, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K
American journal of kidney diseases : the official journal of the National Kidney Foundation
Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2015 Aug; 66(2):313-21.
Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients.
Rhee CM, Kovesdy CP, Ravel VA, Streja E, Brunelli SM, Soohoo M, Sumida K, Molnar MZ, Brent GA, Nguyen DV, Kalantar-Zadeh K
Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes. Diabetes Care. 2017 08; 40(8):1050-1057.
Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes.
You AS, Budoff M, Zeb I, Ahmadi N, Novoa A, Flores F, Hamal S, Kinninger A, Dailing C, Nakata T, Kovesdy CP, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM
Hemodialysis international. International Symposium on Home Hemodialysis
Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort. Hemodial Int. 2022 01; 26(1):57-65.
Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort.
Rhee CM, Budoff M, Brent G, You AS, Stenvinkel P, Novoa A, Flores F, Hamal S, Dailing C, Kinninger A, Nakata T, Kovesdy CP, Nguyen DV, Kalantar-Zadeh K
Serum Thyrotropin Elevation and Coronary Artery Calcification in Hemodialysis Patients. Cardiorenal Med. 2022; 12(3):106-116.
Serum Thyrotropin Elevation and Coronary Artery Calcification in Hemodialysis Patients.
You AS, Kalantar-Zadeh K, Brent GA, Narasaki Y, Daza A, Sim JJ, Kovesdy CP, Nguyen DV, Rhee CM
Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort. Mayo Clin Proc. 2024 Jan; 99(1):39-56.
Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort.
Rhee CM, Brent GA, Kovesdy CP, Soldin OP, Nguyen D, Budoff MJ, Brunelli SM, Kalantar-Zadeh K
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients. Nephrol Dial Transplant. 2015 May; 30(5):724-37.
Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients.
Rhee CM, Leung AM, Kovesdy CP, Lynch KE, Brent GA, Kalantar-Zadeh K
Updates on the management of diabetes in dialysis patients. Semin Dial. 2014 Mar; 27(2):135-45.
Updates on the management of diabetes in dialysis patients.
Rhee CM, Kim S, Gillen DL, Oztan T, Wang J, Mehrotra R, Kuttykrishnan S, Nguyen DV, Brunelli SM, Kovesdy CP, Brent GA, Kalantar-Zadeh K
Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients. J Clin Endocrinol Metab. 2015 Apr; 100(4):1386-95.
Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients.
Rhee CM, Ravel VA, Streja E, Mehrotra R, Kim S, Wang J, Nguyen DV, Kovesdy CP, Brent GA, Kalantar-Zadeh K
Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort. J Clin Endocrinol Metab. 2016 11; 101(11):4054-4061.
Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort.
Rhee CM, You AS, Nguyen DV, Brunelli SM, Budoff MJ, Streja E, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K
Thyroid Status and Mortality in a Prospective Hemodialysis Cohort. J Clin Endocrinol Metab. 2017 05 01; 102(5):1568-1577.
Thyroid Status and Mortality in a Prospective Hemodialysis Cohort.
Rhee CM, Chen Y, You AS, Brunelli SM, Kovesdy CP, Budoff MJ, Brent GA, Kalantar-Zadeh K, Nguyen DV
Clinical journal of the American Society of Nephrology : CJASN
Thyroid Status, Quality of Life, and Mental Health in Patients on Hemodialysis. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1274-1283.
Thyroid Status, Quality of Life, and Mental Health in Patients on Hemodialysis.
Rhee CM, Kalantar-Zadeh K, Ravel V, Streja E, You AS, Brunelli SM, Nguyen DV, Brent GA, Kovesdy CP
Thyroid Status and Death Risk in US Veterans With Chronic Kidney Disease. Mayo Clin Proc. 2018 05; 93(5):573-585.
Thyroid Status and Death Risk in US Veterans With Chronic Kidney Disease.
You AS, Sim JJ, Kovesdy CP, Streja E, Nguyen DV, Brent GA, Kalantar-Zadeh K, Rhee CM
Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality. Nephrol Dial Transplant. 2019 12 01; 34(12):2095-2104.
Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality.
Rhee CM, You AS, Narasaki Y, Brent GA, Sim JJ, Kovesdy CP, Kalantar-Zadeh K, Nguyen DV
Development and Validation of a Prediction Model for Incident Hypothyroidism in a National Chronic Kidney Disease Cohort. J Clin Endocrinol Metab. 2023 10 18; 108(11):e1374-e1383.
Development and Validation of a Prediction Model for Incident Hypothyroidism in a National Chronic Kidney Disease Cohort.
Charles R. Drew University of Medicine and Science
Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements. J Mol Endocrinol. 2004 Aug; 33(1):21-33.
Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements.
Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45.
Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter.
Li QL, Jansen E, Brent GA, Naqvi S, Wilber JF, Friedman TC
Interactions between the prohormone convertase 2 promoter and the thyroid hormone receptor. Endocrinology. 2000 Sep; 141(9):3256-66.
Interactions between the prohormone convertase 2 promoter and the thyroid hormone receptor.
Regulation of prohormone convertase 1 (PC1) by thyroid hormone. Am J Physiol Endocrinol Metab. 2001 Jan; 280(1):E160-70.
Regulation of prohormone convertase 1 (PC1) by thyroid hormone.