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Gregory Brent to Humans

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This is a "connection" page, showing publications Gregory Brent has written about Humans.
Gregory Brent
Connection Strength
2.389
Humans
  1. Pregnancy-Does Promotion of Growth Extend to Thyroid Cancer? J Clin Endocrinol Metab. 2024 Jun 17; 109(7):e1552-e1553.
    View in: PubMed
    Score: 0.089
  2. Weighing in on Thyroid Signaling in the Hypothalamus: Mechanisms and Interface with Metabolic Regulators. Thyroid. 2024 02; 34(2):141-143.
    View in: PubMed
    Score: 0.087
  3. A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 10; 33(10):1140-1149.
    View in: PubMed
    Score: 0.084
  4. Approach to the Patient With a Suppressed TSH. J Clin Endocrinol Metab. 2023 01 17; 108(2):472-482.
    View in: PubMed
    Score: 0.081
  5. Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105.
    View in: PubMed
    Score: 0.075
  6. The Role of Thyroid Hormone in Neuronal Protection. Compr Physiol. 2021 06 01; 11(3):2075-2095.
    View in: PubMed
    Score: 0.072
  7. Thyroid hormone and the brain: Mechanisms of action in development and role in protection and promotion of recovery after brain injury. Pharmacol Ther. 2018 06; 186:176-185.
    View in: PubMed
    Score: 0.058
  8. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Phosphorylation. Methods Mol Biol. 2018; 1801:39-46.
    View in: PubMed
    Score: 0.057
  9. Posttranslational Modification of Thyroid Hormone Nuclear Receptor by Sumoylation. Methods Mol Biol. 2018; 1801:47-59.
    View in: PubMed
    Score: 0.057
  10. Thyroid hormone treatment activates protective pathways in both in?vivo and in?vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130.
    View in: PubMed
    Score: 0.055
  11. Thyroid hormone receptor sumoylation is required for preadipocyte differentiation and proliferation. J Biol Chem. 2015 Mar 20; 290(12):7402-15.
    View in: PubMed
    Score: 0.046
  12. Perchlorate exposure in pregnancy and cognitive outcomes in children: it's not your mother's thyroid. J Clin Endocrinol Metab. 2014 Nov; 99(11):4066-8.
    View in: PubMed
    Score: 0.046
  13. Thyroid hormone regulation of metabolism. Physiol Rev. 2014 Apr; 94(2):355-82.
    View in: PubMed
    Score: 0.044
  14. Commentary on: "American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models," Bianco et al. Thyroid. 2014 Jan; 24(1):1-2.
    View in: PubMed
    Score: 0.043
  15. Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age. Evid Based Nurs. 2014 Jul; 17(3):86.
    View in: PubMed
    Score: 0.043
  16. Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9.
    View in: PubMed
    Score: 0.042
  17. Mechanisms of thyroid hormone action. J Clin Invest. 2012 Sep; 122(9):3035-43.
    View in: PubMed
    Score: 0.040
  18. Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508.
    View in: PubMed
    Score: 0.039
  19. The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70.
    View in: PubMed
    Score: 0.039
  20. The debate over thyroid-function screening in pregnancy. N Engl J Med. 2012 Feb 09; 366(6):562-3.
    View in: PubMed
    Score: 0.038
  21. Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300.
    View in: PubMed
    Score: 0.038
  22. Management of hypothyroidism in pregnancy. Curr Opin Endocrinol Diabetes Obes. 2011 Oct; 18(5):304-9.
    View in: PubMed
    Score: 0.037
  23. Thyroid hormone and COUP-TF1 regulate kallikrein-binding protein (KBP) gene expression. Endocrinology. 2011 Mar; 152(3):1143-53.
    View in: PubMed
    Score: 0.035
  24. Environmental exposures and autoimmune thyroid disease. Thyroid. 2010 Jul; 20(7):755-61.
    View in: PubMed
    Score: 0.034
  25. The impact of perchlorate exposure in early pregnancy: is it safe to drink the water? J Clin Endocrinol Metab. 2010 Jul; 95(7):3154-7.
    View in: PubMed
    Score: 0.034
  26. Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab. 2010 Mar; 21(3):166-73.
    View in: PubMed
    Score: 0.033
  27. Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50.
    View in: PubMed
    Score: 0.031
  28. Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52.
    View in: PubMed
    Score: 0.030
  29. Clinical practice. Graves' disease. N Engl J Med. 2008 Jun 12; 358(24):2594-605.
    View in: PubMed
    Score: 0.029
  30. Stealth sequences in reporter gene vectors confound studies of T3-regulated negative gene expression. Thyroid. 2008 Jun; 18(6):593-5.
    View in: PubMed
    Score: 0.029
  31. Retinoic acid stimulation of the sodium/iodide symporter in MCF-7 breast cancer cells is mediated by the insulin growth factor-I/phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase signaling pathways. J Clin Endocrinol Metab. 2008 May; 93(5):1884-92.
    View in: PubMed
    Score: 0.029
  32. Thyroid health and the environment. Thyroid. 2007 Sep; 17(9):807-9.
    View in: PubMed
    Score: 0.028
  33. Diagnosing thyroid dysfunction in pregnant women: Is case finding enough? J Clin Endocrinol Metab. 2007 Jan; 92(1):39-41.
    View in: PubMed
    Score: 0.027
  34. Enhancement of sodium/iodide symporter expression in thyroid and breast cancer. Endocr Relat Cancer. 2006 Sep; 13(3):797-826.
    View in: PubMed
    Score: 0.026
  35. 2025 American Thyroid Association Management Guidelines for Adult Patients with Differentiated Thyroid Cancer. Thyroid. 2025 08; 35(8):841-985.
    View in: PubMed
    Score: 0.024
  36. Differential regulation of sodium/iodide symporter gene expression by nuclear receptor ligands in MCF-7 breast cancer cells. Endocrinology. 2005 Jul; 146(7):3059-69.
    View in: PubMed
    Score: 0.024
  37. Rapid progression from subclinical to symptomatic overt hypothyroidism. Endocr Pract. 2005 Mar-Apr; 11(2):115-9.
    View in: PubMed
    Score: 0.023
  38. Introduction. The impact of maternal thyroid diseases on the developing fetus: implications for diagnosis, treatment, and screening. Summary of proceedings, workshop organization, program, and participants. Thyroid. 2005 Jan; 15(1):36-40.
    View in: PubMed
    Score: 0.023
  39. Thyroid function inside and outside of pregnancy: what do we know and what don't we know? Thyroid. 2005 Jan; 15(1):54-9.
    View in: PubMed
    Score: 0.023
  40. Systemic retinoic acid treatment induces sodium/iodide symporter expression and radioiodide uptake in mouse breast cancer models. Cancer Res. 2004 Jan 01; 64(1):415-22.
    View in: PubMed
    Score: 0.022
  41. Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort. Mayo Clin Proc. 2024 Jan; 99(1):39-56.
    View in: PubMed
    Score: 0.022
  42. Development and Validation of a Prediction Model for Incident Hypothyroidism in a National Chronic Kidney Disease Cohort. J Clin Endocrinol Metab. 2023 10 18; 108(11):e1374-e1383.
    View in: PubMed
    Score: 0.021
  43. The modified firefly luciferase reporter gene (luc+) but not Renilla luciferase is induced by all-trans retinoic acid in MCF-7 breast cancer cells. Breast Cancer Res Treat. 2003 Mar; 78(1):119-26.
    View in: PubMed
    Score: 0.020
  44. A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol. 2002 Oct; 16(10):2266-82.
    View in: PubMed
    Score: 0.020
  45. Serum Thyrotropin Elevation and Coronary Artery Calcification in Hemodialysis Patients. Cardiorenal Med. 2022; 12(3):106-116.
    View in: PubMed
    Score: 0.019
  46. Serum Thyroglobulin Measurement Following Surgery Without Radioactive Iodine for Differentiated Thyroid Cancer: A Systematic Review. Thyroid. 2022 06; 32(6):613-639.
    View in: PubMed
    Score: 0.019
  47. Nonthyroidal illness syndrome: evaluation of thyroid function in sick patients. Endocrinol Metab Clin North Am. 2002 Mar; 31(1):159-72.
    View in: PubMed
    Score: 0.019
  48. Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells. Endocrinology. 2001 Aug; 142(8):3369-79.
    View in: PubMed
    Score: 0.018
  49. Elevated serum thyrotropin levels and endothelial dysfunction in a prospective hemodialysis cohort. Hemodial Int. 2022 01; 26(1):57-65.
    View in: PubMed
    Score: 0.018
  50. Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific. J Clin Invest. 2001 Jul; 108(1):97-105.
    View in: PubMed
    Score: 0.018
  51. Retinoic acid induces sodium/iodide symporter gene expression and radioiodide uptake in the MCF-7 breast cancer cell line. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8519-24.
    View in: PubMed
    Score: 0.017
  52. Association of Subclinical Hypothyroidism and Cardiovascular Disease With Mortality. JAMA Netw Open. 2020 02 05; 3(2):e1920745.
    View in: PubMed
    Score: 0.017
  53. Association of thyroid status prior to transition to end-stage renal disease with early dialysis mortality. Nephrol Dial Transplant. 2019 12 01; 34(12):2095-2104.
    View in: PubMed
    Score: 0.016
  54. Maternal hypothyroidism: recognition and management. Thyroid. 1999 Jul; 9(7):661-5.
    View in: PubMed
    Score: 0.016
  55. Thyroid hormone action: down novel paths. Focus on "thyroid hormone induces activation of mitogen-activated protein kinase in cultured cells". Am J Physiol. 1999 05; 276(5):C1012-3.
    View in: PubMed
    Score: 0.016
  56. Older Adults with Cognitive Impairment Have Sex: More Evidence Against the Medical Myth of Sexless Aging. J Am Geriatr Soc. 2018 10; 66(10):1870-1871.
    View in: PubMed
    Score: 0.015
  57. Thyroid Status and Death Risk in US Veterans With Chronic Kidney Disease. Mayo Clin Proc. 2018 05; 93(5):573-585.
    View in: PubMed
    Score: 0.015
  58. Mechanisms of thyroid hormone action. Implications for the clinical manifestation of thyrotoxicosis. Endocrinol Metab Clin North Am. 1998 Mar; 27(1):1-23.
    View in: PubMed
    Score: 0.014
  59. Thyroid Status, Quality of Life, and Mental Health in Patients on Hemodialysis. Clin J Am Soc Nephrol. 2017 Aug 07; 12(8):1274-1283.
    View in: PubMed
    Score: 0.014
  60. Association of Glycemic Status During Progression of Chronic Kidney Disease With Early Dialysis Mortality in Patients With Diabetes. Diabetes Care. 2017 08; 40(8):1050-1057.
    View in: PubMed
    Score: 0.014
  61. Thyroid Status and Mortality in a Prospective Hemodialysis Cohort. J Clin Endocrinol Metab. 2017 05 01; 102(5):1568-1577.
    View in: PubMed
    Score: 0.014
  62. Maternal thyroid function: interpretation of thyroid function tests in pregnancy. Clin Obstet Gynecol. 1997 Mar; 40(1):3-15.
    View in: PubMed
    Score: 0.013
  63. 2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum. Thyroid. 2017 03; 27(3):315-389.
    View in: PubMed
    Score: 0.013
  64. Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort. J Clin Endocrinol Metab. 2016 11; 101(11):4054-4061.
    View in: PubMed
    Score: 0.013
  65. Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action. Thyroid. 2016 Apr; 26(4):479-80.
    View in: PubMed
    Score: 0.013
  66. A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T). J Clin Endocrinol Metab. 2015 Jul; 100(7):2511-4.
    View in: PubMed
    Score: 0.012
  67. Association of Adiponectin With Body Composition and Mortality in Hemodialysis Patients. Am J Kidney Dis. 2015 Aug; 66(2):313-21.
    View in: PubMed
    Score: 0.012
  68. Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients. J Clin Endocrinol Metab. 2015 Apr; 100(4):1386-95.
    View in: PubMed
    Score: 0.012
  69. A review: Radiographic iodinated contrast media-induced thyroid dysfunction. J Clin Endocrinol Metab. 2015 Feb; 100(2):376-83.
    View in: PubMed
    Score: 0.011
  70. The molecular basis of thyroid hormone action. N Engl J Med. 1994 Sep 29; 331(13):847-53.
    View in: PubMed
    Score: 0.011
  71. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. Thyroid. 2014 Mar; 24(3):407-9.
    View in: PubMed
    Score: 0.011
  72. Updates on the management of diabetes in dialysis patients. Semin Dial. 2014 Mar; 27(2):135-45.
    View in: PubMed
    Score: 0.011
  73. Classification and proposed nomenclature for inherited defects of thyroid hormone action, cell transport, and metabolism. J Clin Endocrinol Metab. 2014 Mar; 99(3):768-70.
    View in: PubMed
    Score: 0.011
  74. Thyroid functional disease: an under-recognized cardiovascular risk factor in kidney disease patients. Nephrol Dial Transplant. 2015 May; 30(5):724-37.
    View in: PubMed
    Score: 0.011
  75. Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors. Mol Endocrinol. 1992 Oct; 6(10):1527-37.
    View in: PubMed
    Score: 0.010
  76. Thyroid hormone regulation of gene expression. Annu Rev Physiol. 1991; 53:17-35.
    View in: PubMed
    Score: 0.009
  77. Increased need for thyroxine during pregnancy in women with primary hypothyroidism. N Engl J Med. 1990 Jul 12; 323(2):91-6.
    View in: PubMed
    Score: 0.009
  78. Reversible alteration of red cell lithium-sodium countertransport in patients with thyroid disease. J Clin Endocrinol Metab. 1989 Feb; 68(2):322-8.
    View in: PubMed
    Score: 0.008
  79. Relationship between the concentration and rate of change of calcium and serum intact parathyroid hormone levels in normal humans. J Clin Endocrinol Metab. 1988 Nov; 67(5):944-50.
    View in: PubMed
    Score: 0.008
  80. Multihormonal regulation of the human, rat, and bovine growth hormone promoters: differential effects of 3',5'-cyclic adenosine monophosphate, thyroid hormone, and glucocorticoids. Mol Endocrinol. 1988 Sep; 2(9):792-8.
    View in: PubMed
    Score: 0.007
  81. Thyroid hormone regulates endogenous amyloid-beta precursor protein gene expression and processing in both in vitro and in vivo models. Thyroid. 2006 Dec; 16(12):1207-13.
    View in: PubMed
    Score: 0.007
  82. Patients with severe nonthyroidal illness and serum thyrotropin concentrations in the hypothyroid range. Am J Med. 1986 Sep; 81(3):463-6.
    View in: PubMed
    Score: 0.007
  83. Thyroxine therapy in patients with severe nonthyroidal illnesses and low serum thyroxine concentration. J Clin Endocrinol Metab. 1986 Jul; 63(1):1-8.
    View in: PubMed
    Score: 0.006
  84. Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation. Cancer Gene Ther. 2006 Jan 01; 13(1):74-81.
    View in: PubMed
    Score: 0.006
  85. Anaplastic thyroid carcinoma with thyrotoxicosis and hypoparathyroidism. Endocr Pract. 2005 Jul-Aug; 11(4):281-4.
    View in: PubMed
    Score: 0.006
  86. Resistance to thyroid hormone in Hashimoto's thyroiditis. N Engl J Med. 2005 Feb 03; 352(5):517-8.
    View in: PubMed
    Score: 0.006
  87. Thyroid hormone regulation of prohormone convertase 1 (PC1): regional expression in rat brain and in vitro characterization of negative thyroid hormone response elements. J Mol Endocrinol. 2004 Aug; 33(1):21-33.
    View in: PubMed
    Score: 0.006
  88. Serum angiotensin-converting enzyme in severe nonthyroidal illnesses associated with low serum thyroxine concentration. Ann Intern Med. 1984 May; 100(5):680-3.
    View in: PubMed
    Score: 0.006
  89. Enhanced expression of nicotinamide N-methyltransferase in human papillary thyroid carcinoma cells. J Clin Endocrinol Metab. 2003 Oct; 88(10):4990-6.
    View in: PubMed
    Score: 0.005
  90. Follow-up of newborns with elevated screening T4 concentrations. J Pediatr. 2003 Sep; 143(3):296-301.
    View in: PubMed
    Score: 0.005
  91. Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells. Cancer Res. 2003 Aug 15; 63(16):5065-72.
    View in: PubMed
    Score: 0.005
  92. A GC box in the human sodium iodide symporter gene promoter is essential for full activity. Thyroid. 2002 Feb; 12(2):107-14.
    View in: PubMed
    Score: 0.005
  93. The Kaposi sarcoma-associated herpesvirus (KSHV) induces cellular interleukin 6 expression: role of the KSHV latency-associated nuclear antigen and the AP1 response element. Blood. 2002 Jan 15; 99(2):649-54.
    View in: PubMed
    Score: 0.005
  94. Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer. Cancer Gene Ther. 2001 Aug; 8(8):612-8.
    View in: PubMed
    Score: 0.005
  95. Induction of follicle formation in long-term cultured normal human thyroid cells treated with thyrotropin stimulates iodide uptake but not sodium/iodide symporter messenger RNA and protein expression. J Endocrinol. 2000 Oct; 167(1):125-35.
    View in: PubMed
    Score: 0.004
  96. Interactions between the prohormone convertase 2 promoter and the thyroid hormone receptor. Endocrinology. 2000 Sep; 141(9):3256-66.
    View in: PubMed
    Score: 0.004
  97. Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation. Nat Genet. 1997 Oct; 17(2):179-81.
    View in: PubMed
    Score: 0.004
  98. Structural features of thyroid hormone response elements that increase susceptibility to inhibition by an RTH mutant thyroid hormone receptor. Endocrinology. 1996 Jul; 137(7):2833-41.
    View in: PubMed
    Score: 0.003
  99. Prospective studies of thyroid function in patients receiving gold therapy. Thyroid. 1995 Apr; 5(2):113-6.
    View in: PubMed
    Score: 0.003
  100. Review of antithyroid drug use during pregnancy and report of a case of aplasia cutis. Thyroid. 1994; 4(1):129-33.
    View in: PubMed
    Score: 0.003
  101. Levothyroxine therapy in patients with thyroid disease. Ann Intern Med. 1993 Sep 15; 119(6):492-502.
    View in: PubMed
    Score: 0.003
  102. Adrenocorticotropin stimulation of aldosterone: prolonged continuous versus pulsatile infusion. J Clin Endocrinol Metab. 1989 Nov; 69(5):1028-32.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.