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overview Fibrosis is a leading cause of organ failure worldwide when normal tissue is replaced with an excess connective tissue. Recent studies have provided new evidence for an association between low serum Vitamin D and cardiovascular disease (CVD) risk factors, as well as other medical conditions such as stroke, prostate, colon, breast cancer, multiple sclerosis, and infections such as tuberculosis. The goal of my research is to establish whether vitamin D exerts an anti-fibrotic phenotype in specific cell lines and in selected animal models of tissue degeneration suggesting that supplementation with vitamin D could be used as an anti-fibrotic strategy in therapeutic treatment of chronic diseases such as renal, cardiac and lung fibrosis.
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  • Stroke