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Basil O. Ibe, PhD

TitleAdjunct Professor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentBiomedical Science Ed.
Address1731 E. 120th Street
Los Angeles CA 90059
PhoneNot Available
FaxNot Available
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    Bibliographic
    selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hanouni M, Bernal G, McBride S, Narvaez VR, Ibe BO. Hypoxia and hyperoxia potentiate PAF receptor-mediated effects in newborn ovine pulmonary arterial smooth muscle cells: significance in oxygen therapy of PPHN. Physiol Rep. 2016 Jun; 4(12). PMID: 27354543; PMCID: PMC4923239.
      Citations: 4     Fields:    Translation:AnimalsCells
    2. Koos BJ, Rajaee A, Ibe B, Guerra C, Kruger L. Thalamic mediation of hypoxic respiratory depression in lambs. Am J Physiol Regul Integr Comp Physiol. 2016 Apr 01; 310(7):R586-95. PMID: 26818057; PMCID: PMC4867384.
      Citations: 7     Fields:    Translation:Animals
    3. Ogbozor UD, Opene M, Renteria LS, McBride S, Ibe BO. Mechanism by which nuclear factor-kappa beta (NF-kB) regulates ovine fetal pulmonary vascular smooth muscle cell proliferation. Mol Genet Metab Rep. 2015 Sep; 4:11-8. PMID: 26966681; PMCID: PMC4777924.
      Citations: 6     
    4. Opene M, Kurantsin-Mills J, Husain S, Ibe BO. Sickle erythrocytes and platelets augment lung leukotriene synthesis with downregulation of anti-inflammatory proteins: relevance in the pathology of the acute chest syndrome. Pulm Circ. 2014 Sep; 4(3):482-95. PMID: 25621162; PMCID: PMC4278608.
      Citations: 6     
    5. Morales E, Sakurai R, Husain S, Paek D, Gong M, Ibe B, Li Y, Husain M, Torday JS, Rehan VK. Nebulized PPAR? agonists: a novel approach to augment neonatal lung maturation and injury repair in rats. Pediatr Res. 2014 May; 75(5):631-40. PMID: 24488089; PMCID: PMC4016987.
      Citations: 17     Fields:    Translation:Animals
    6. Renteria LS, Cruz E, Ibe BO. Platelet-activating factor synthesis and receptor-mediated signaling are downregulated in ovine newborn lungs: relevance in postnatal pulmonary adaptation and persistent pulmonary hypertension of the newborn. J Dev Orig Health Dis. 2013 Dec; 4(6):458-69. PMID: 24924225.
      Citations: 2     Fields:    
    7. Renteria LS, Austin M, Lazaro M, Andrews MA, Lustina J, Raj JU, Ibe BO. RhoA-Rho kinase and platelet-activating factor stimulation of ovine foetal pulmonary vascular smooth muscle cell proliferation. Cell Prolif. 2013 Oct; 46(5):563-75. PMID: 24033386; PMCID: PMC3788060.
      Citations: 6     Fields:    Translation:AnimalsCells
    8. Bae R, Arteaga A, Raj JU, Ibe BO. Albuterol isomers modulate platelet-activating factor synthesis and receptor signaling in human bronchial smooth muscle cells. Int Arch Allergy Immunol. 2012; 158(1):18-26. PMID: 22212397.
      Citations: 2     Fields:    Translation:HumansCells
    9. Rehan VK, Sakurai R, Corral J, Krebs M, Ibe B, Ihida-Stansbury K, Torday JS. Antenatally administered PPAR-gamma agonist rosiglitazone prevents hyperoxia-induced neonatal rat lung injury. Am J Physiol Lung Cell Mol Physiol. 2010 Nov; 299(5):L672-80. PMID: 20729387; PMCID: PMC2980388.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    10. Renteria LS, Raj JU, Ibe BO. Prolonged hypoxia modulates platelet activating factor receptor-mediated responses by fetal ovine pulmonary vascular smooth muscle cells. Mol Genet Metab. 2010 Dec; 101(4):400-8. PMID: 20813571; PMCID: PMC2991540.
      Citations: 3     Fields:    Translation:AnimalsCells
    11. Sheng L, Zhou W, Hislop AA, Ibe BO, Longo LD, Raj JU. Role of epidermal growth factor receptor in ovine fetal pulmonary vascular remodeling following exposure to high altitude long-term hypoxia. High Alt Med Biol. 2009; 10(4):365-72. PMID: 20043379; PMCID: PMC3140299.
      Citations: 9     Fields:    Translation:AnimalsCells
    12. Ibe BO, Abdallah MF, Portugal AM, Raj JU. Platelet-activating factor stimulates ovine foetal pulmonary vascular smooth muscle cell proliferation: role of nuclear factor-kappa B and cyclin-dependent kinases. Cell Prolif. 2008 Apr; 41(2):208-29. PMID: 18336468; PMCID: PMC6496610.
      Citations: 10     Fields:    Translation:AnimalsCells
    13. Ibe BO, Abdallah MF, Raj JU. Mechanisms by which S-albuterol induces human bronchial smooth muscle cell proliferation. Int Arch Allergy Immunol. 2008; 146(4):321-33. PMID: 18362475.
      Citations: 4     Fields:    Translation:HumansCells
    14. Bixby CE, Ibe BO, Abdallah MF, Zhou W, Hislop AA, Longo LD, Raj JU. Role of platelet-activating factor in pulmonary vascular remodeling associated with chronic high altitude hypoxia in ovine fetal lambs. Am J Physiol Lung Cell Mol Physiol. 2007 Dec; 293(6):L1475-82. PMID: 17951313.
      Citations: 16     Fields:    Translation:AnimalsCells
    15. John TA, Ibe BO, Raj JU. Regulation of endothelial nitric oxide synthase: involvement of protein kinase G 1 beta, serine 116 phosphorylation and lipid structures. Clin Exp Pharmacol Physiol. 2008 Feb; 35(2):148-58. PMID: 17892503.
      Citations: 8     Fields:    Translation:AnimalsCells
    16. Zhou W, Ibe BO, Raj JU. Platelet-activating factor induces ovine fetal pulmonary venous smooth muscle cell proliferation: role of epidermal growth factor receptor transactivation. Am J Physiol Heart Circ Physiol. 2007 Jun; 292(6):H2773-81. PMID: 17322418.
      Citations: 15     Fields:    Translation:AnimalsCells
    17. Ibe BO, Ameer A, Portugal AM, Renteria L, Raj JU. Platelet-activating factor modulates activity of cyclic nucleotides in fetal ovine pulmonary vascular smooth muscle. J Pharmacol Exp Ther. 2007 Feb; 320(2):728-37. PMID: 17085546.
      Citations: 7     Fields:    Translation:Animals
    18. John TA, Ibe BO, Usha Raj J. Oxygen alters caveolin-1 and nitric oxide synthase-3 functions in ovine fetal and neonatal lung microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2006 Nov; 291(5):L1079-93. PMID: 16997880.
      Citations: 4     Fields:    Translation:AnimalsCells
    19. Chen JX, Ibe BO, Ma SX. Nitric oxide modulation of norepinephrine production in acupuncture points. Life Sci. 2006 Nov 02; 79(23):2157-64. PMID: 16890244.
      Citations: 10     Fields:    Translation:Animals
    20. Ibe BO, Portugal AM, Raj JU. Levalbuterol inhibits human airway smooth muscle cell proliferation: therapeutic implications in the management of asthma. Int Arch Allergy Immunol. 2006; 139(3):225-36. PMID: 16446544.
      Citations: 7     Fields:    Translation:HumansCells
    21. Ibe BO, Portugal AM, Chaturvedi S, Raj JU. Oxygen-dependent PAF receptor binding and intracellular signaling in ovine fetal pulmonary vascular smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2005 May; 288(5):L879-86. PMID: 15618453.
      Citations: 9     Fields:    Translation:AnimalsCells
    22. Ibe BO, Portugal AM, Usha Raj J. Metabolism of platelet activating factor by intrapulmonary vascular smooth muscle cells. Effect of oxygen on phospholipase A2 protein expression and activities of acetyl-CoA acetyltransferase and cholinephosphotransferase. Mol Genet Metab. 2002 Nov; 77(3):237-48. PMID: 12409272.
      Citations: 7     Fields:    Translation:Animals
    23. Ibe BO, Pham HH, K??p? P, Raj JU. Maturational changes in ovine pulmonary metabolism of platelet-activating factor: implications for postnatal adaptation. Mol Genet Metab. 2001 Nov; 74(3):385-95. PMID: 11708870.
      Citations: 2     Fields:    Translation:AnimalsCells
    24. Ibe BO, Raj JU. Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor. Exp Lung Res. 2001 Jun; 27(4):331-48. PMID: 11400860.
      Citations: 1     Fields:    Translation:Animals
    25. Ibe BO, Sander FC, Raj JU. Platelet-activating factor receptors in lamb lungs are downregulated immediately after birth. Am J Physiol Heart Circ Physiol. 2000 Apr; 278(4):H1168-76. PMID: 10749711.
      Citations: 6     Fields:    Translation:AnimalsCells
    26. Ibe BO, Sander FC, Raj JU. Platelet activating factor acetylhydrolase activity in lamb lungs is up-regulated in the immediate newborn period. Mol Genet Metab. 2000 Jan; 69(1):46-55. PMID: 10655157.
      Citations: 1     Fields:    Translation:AnimalsCells
    27. Okogbule-Wonodi AC, Ibe BO, Yue BW, Hsu S, Raj JU. Phosphodiesterase activity in intrapulmonary arteries and veins of perinatal lambs. Mol Genet Metab. 1998 Nov; 65(3):229-37. PMID: 9851888.
      Citations: 4     Fields:    Translation:AnimalsCells
    28. Ibe BO, Hibler S, Raj JU. Platelet-activating factor modulates pulmonary vasomotor tone in the perinatal lamb. J Appl Physiol (1985). 1998 Sep; 85(3):1079-85. PMID: 9729586.
      Citations: 8     Fields:    Translation:Animals
    29. Oh SO, Ibe BO, Johnson C, Kurantsin-Mills J, Raj JU. Platelet-activating factor in plasma of patients with sickle cell disease in steady state. J Lab Clin Med. 1997 Aug; 130(2):191-6. PMID: 9280146.
      Citations: 7     Fields:    Translation:HumansCells
    30. Ibe BO, Anderson JM, Raj JU. Leukotriene synthesis by isolated perinatal ovine intrapulmonary vessels correlates with age-related changes in 5-lipoxygenase protein. Biochem Mol Med. 1997 Jun; 61(1):63-71. PMID: 9232199.
      Citations: 2     Fields:    Translation:Animals
    31. Ibe BO, Morris J, Kurantsin-Mills J, Raj JU. Sickle erythrocytes induce prostacyclin and thromboxane synthesis by isolated perfused rat lungs. Am J Physiol. 1997 Apr; 272(4 Pt 1):L597-602. PMID: 9142930.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    32. Gao Y, Zhou H, Ibe BO, Raj JU. Prostaglandins E2 and I2 cause greater relaxations in pulmonary veins than in arteries of newborn lambs. J Appl Physiol (1985). 1996 Dec; 81(6):2534-9. PMID: 9018503.
      Citations: 8     Fields:    Translation:Animals
    33. Ibe BO, Hillyard RM, Raj JU. Heterogeneity in prostacyclin and thromboxane synthesis in ovine pulmonary vascular tree: effect of age and oxygen tension. Exp Lung Res. 1996 May-Jun; 22(3):351-74. PMID: 8792126.
      Citations: 3     Fields:    Translation:Animals
    34. Salva AM, Ibe BO, Cliborn E, Reyes G, Raj JU. Hypoxia attenuates metabolism of platelet activating factor by fetal and newborn lamb lungs. J Lipid Res. 1996 Apr; 37(4):783-9. PMID: 8732778.
      Citations: 2     Fields:    Translation:AnimalsCells
    35. Ibe BO, Okogbule-Wonodi AC, Raj JU. Antenatal glucocorticoid treatment attenuates immediate postnatal prostacyclin and thromboxane levels in plasma of very preterm lambs. Biol Neonate. 1996; 69(3):153-64. PMID: 8672599.
      Citations:    Fields:    Translation:Animals
    36. Ibe BO, Raj JU. Developmental differences in production of lipoxygenase metabolites by ovine lungs. Exp Lung Res. 1995 May-Jun; 21(3):385-405. PMID: 7621776.
      Citations: 1     Fields:    Translation:AnimalsCells
    37. Kurantsin-Mills J, Ibe BO, Natta CL, Raj JU, Siegel RS, Lessin LS. Elevated urinary levels of thromboxane and prostacyclin metabolities in sickle cell disease reflects activated platelets in the circulation. Br J Haematol. 1994 Jul; 87(3):580-5. PMID: 7993800.
      Citations: 4     Fields:    Translation:HumansCells
    38. Ibe BO, Raj JU. Metabolism of N-methylcarbazole by rat lung microsomes. Exp Lung Res. 1994 May-Jun; 20(3):207-22. PMID: 7925139.
      Citations:    Fields:    Translation:AnimalsCells
    39. Filler SG, Ibe BO, Ibrahim AS, Ghannoum MA, Raj JU, Edwards JE. Mechanisms by which Candida albicans induces endothelial cell prostaglandin synthesis. Infect Immun. 1994 Mar; 62(3):1064-9. PMID: 8112841; PMCID: PMC186225.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    40. Ibe BO, Kurantsin-Mills J, Raj JU, Lessin LS. Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. Eur J Clin Invest. 1994 Jan; 24(1):57-64. PMID: 8187808.
      Citations: 4     Fields:    Translation:HumansCells
    41. Toga H, Hibler S, Ibe BO, Raj JU. Vascular effects of platelet-activating factor in lambs: role of cyclo- and lipoxygenase. J Appl Physiol (1985). 1992 Dec; 73(6):2559-66. PMID: 1490969.
      Citations: 6     Fields:    Translation:Animals
    42. Toga H, Ibe BO, Raj JU. In vitro responses of ovine intrapulmonary arteries and veins to endothelin-1. Am J Physiol. 1992 Jul; 263(1 Pt 1):L15-21. PMID: 1636725.
      Citations: 4     Fields:    Translation:Animals
    43. Raj JU, Toga H, Ibe BO, Anderson J. Effects of endothelin, platelet activating factor and thromboxane A2 in ferret lungs. Respir Physiol. 1992 Apr-May; 88(1-2):129-40. PMID: 1626132.
      Citations: 11     Fields:    Translation:Animals
    44. Ibe BO, Raj JU. Endogenous arachidonic acid metabolism by calcium ionophore stimulated ferret lungs. Effect of age, hypoxia. Lab Invest. 1992 Mar; 66(3):370-7. PMID: 1538590.
      Citations: 1     Fields:    Translation:Animals
    45. Ibe BO, Raj JU. Metabolism of endogenous arachidonic acid by isolated lungs of neonatal and adult rabbits stimulated with calcium ionophore: effect of hypoxia. Exp Lung Res. 1992 Jan-Mar; 18(1):69-85. PMID: 1572326.
      Citations: 2     Fields:    Translation:Animals
    46. Filler SG, Ibe BO, Luckett PM, Raj JU, Edwards JE. Candida albicans stimulates endothelial cell eicosanoid production. J Infect Dis. 1991 Nov; 164(5):928-35. PMID: 1940471.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    47. Kaapa P, Raj JU, Ibe BO, Anderson J. Effect of pentoxifylline in rabbit pulmonary circulation: influence of age and vasomotor tone. Am J Physiol. 1991 Oct; 261(4 Pt 2):H975-81. PMID: 1928416.
      Citations: 1     Fields:    Translation:Animals
    48. Kaapa P, Raj JU, Ibe BO, Anderson J. Vasoconstrictor response to prostacyclin in rabbit pulmonary circulation. Respir Physiol. 1991 Aug; 85(2):193-204. PMID: 1947459.
      Citations:    Fields:    Translation:Animals
    49. Ibe BO, Isenberg WB, Raj JU. Endogenous arachidonic acid metabolism by calcium ionophore A23187-stimulated lamb lungs: effect of hypoxia. Am J Respir Cell Mol Biol. 1991 Apr; 4(4):379-85. PMID: 1901720.
      Citations: 1     Fields:    Translation:Animals
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