Platelet Activating Factor
"Platelet Activating Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phospholipid derivative formed by PLATELETS; BASOPHILS; NEUTROPHILS; MONOCYTES; and MACROPHAGES. It is a potent platelet aggregating agent and inducer of systemic anaphylactic symptoms, including HYPOTENSION; THROMBOCYTOPENIA; NEUTROPENIA; and BRONCHOCONSTRICTION.
| Descriptor ID |
D010972
|
| MeSH Number(s) |
D02.033.100.291.211.500 D02.092.063.291.211.500 D02.092.877.883.333.710 D02.675.276.232.710 D10.570.755.375.760.400.985.910 D23.119.865 D23.469.050.600
|
| Concept/Terms |
Platelet Activating Factor- Platelet Activating Factor
- Factor, Platelet Activating
- Phosphorylcholine, Acetyl Glyceryl Ether
- Platelet Aggregating Factor
- Aggregating Factor, Platelet
- Platelet Aggregation Enhancing Factor
- AGEPC
- Thrombocyte Aggregating Activity
- 1-Alkyl-2-acetyl-sn-glycerophosphocholine
- 1 Alkyl 2 acetyl sn glycerophosphocholine
- Acetyl Glyceryl Ether Phosphorylcholine
- PAF-Acether
- PAF Acether
- Platelet-Activating Substance
- Platelet Activating Substance
|
Below are MeSH descriptors whose meaning is more general than "Platelet Activating Factor".
Below are MeSH descriptors whose meaning is more specific than "Platelet Activating Factor".
This graph shows the total number of publications written about "Platelet Activating Factor" by people in this website by year, and whether "Platelet Activating Factor" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Platelet Activating Factor" by people in Profiles.
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RhoA-Rho kinase and platelet-activating factor stimulation of ovine foetal pulmonary vascular smooth muscle cell proliferation. Cell Prolif. 2013 Oct; 46(5):563-75.
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Albuterol isomers modulate platelet-activating factor synthesis and receptor signaling in human bronchial smooth muscle cells. Int Arch Allergy Immunol. 2012; 158(1):18-26.
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Prolonged hypoxia modulates platelet activating factor receptor-mediated responses by fetal ovine pulmonary vascular smooth muscle cells. Mol Genet Metab. 2010 Dec; 101(4):400-8.
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Platelet-activating factor stimulates ovine foetal pulmonary vascular smooth muscle cell proliferation: role of nuclear factor-kappa B and cyclin-dependent kinases. Cell Prolif. 2008 Apr; 41(2):208-29.
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Mechanisms by which S-albuterol induces human bronchial smooth muscle cell proliferation. Int Arch Allergy Immunol. 2008; 146(4):321-33.
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Role of platelet-activating factor in pulmonary vascular remodeling associated with chronic high altitude hypoxia in ovine fetal lambs. Am J Physiol Lung Cell Mol Physiol. 2007 Dec; 293(6):L1475-82.
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Platelet-activating factor induces ovine fetal pulmonary venous smooth muscle cell proliferation: role of epidermal growth factor receptor transactivation. Am J Physiol Heart Circ Physiol. 2007 Jun; 292(6):H2773-81.
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Platelet-activating factor modulates activity of cyclic nucleotides in fetal ovine pulmonary vascular smooth muscle. J Pharmacol Exp Ther. 2007 Feb; 320(2):728-37.
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Metabolism of platelet activating factor by intrapulmonary vascular smooth muscle cells. Effect of oxygen on phospholipase A2 protein expression and activities of acetyl-CoA acetyltransferase and cholinephosphotransferase. Mol Genet Metab. 2002 Nov; 77(3):237-48.
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Maturational changes in ovine pulmonary metabolism of platelet-activating factor: implications for postnatal adaptation. Mol Genet Metab. 2001 Nov; 74(3):385-95.