"Serotonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.
Descriptor ID |
D012701
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MeSH Number(s) |
D02.092.211.215.801.852 D03.633.100.473.914.814 D23.469.050.650
|
Concept/Terms |
Serotonin- Serotonin
- 5-Hydroxytryptamine
- 5 Hydroxytryptamine
- Hippophaine
- 3-(2-Aminoethyl)-1H-indol-5-ol
- Enteramine
- 5-HT
|
Below are MeSH descriptors whose meaning is more general than "Serotonin".
Below are MeSH descriptors whose meaning is more specific than "Serotonin".
This graph shows the total number of publications written about "Serotonin" by people in this website by year, and whether "Serotonin" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2010 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serotonin" by people in Profiles.
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Further characterization of tryptophan metabolism and its dysregulation in fibroids. F S Sci. 2022 11; 3(4):392-400.
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L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin. J Biol Chem. 2011 Oct 07; 286(40):34800-8.
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Serotonin-induced region-specific responses of the arcuate and ventromedial hypothalamic nuclei. Int J Neurosci. 2010 May; 120(5):386-95.
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A paucity of colonic enteroendocrine and/or enterochromaffin cells characterizes a subset of patients with chronic unexplained diarrhea/malabsorption. Hum Pathol. 2009 Jul; 40(7):1006-14.
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CYP2D6 genotype in relation to perphenazine concentration and pituitary pharmacodynamic tissue sensitivity in Asians: CYP2D6-serotonin-dopamine crosstalk revisited. Pharmacogenet Genomics. 2007 May; 17(5):339-47.
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The development of prolactin, growth hormone, alpha-melanocyte-stimulating hormone and monoaminergic systems in the rat. Monogr Neural Sci. 1986; 12:1-6.