Header Logo

Connection

Ekihiro Seki to Male

Back to Details
This is a "connection" page, showing publications Ekihiro Seki has written about Male.
Ekihiro Seki
Connection Strength
1.699
Male
  1. Loss of fungal sensing exacerbates liver injury in a murine model of MASLD. JCI Insight. 2026 Apr 22; 11(8).
    View in: PubMed
    Score: 0.134
  2. Repurposing of the analgesic Neurotropin for MASLD/MASH treatment. Hepatol Commun. 2024 08 01; 8(8).
    View in: PubMed
    Score: 0.120
  3. Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient L-amino acid-defined diet-induced murine model. Arch Pharm Res. 2021 Feb; 44(2):230-240.
    View in: PubMed
    Score: 0.094
  4. Inflammation and Liver Cancer: Molecular Mechanisms and Therapeutic Targets. Semin Liver Dis. 2019 02; 39(1):26-42.
    View in: PubMed
    Score: 0.082
  5. MafG, A Novel Target of FXR that Regulates Bile Acid Homeostasis. Gastroenterology. 2015 Dec; 149(7):1981-3.
    View in: PubMed
    Score: 0.066
  6. Reply: To PMID 23996730. Hepatology. 2014 Sep; 60(3):1114-5.
    View in: PubMed
    Score: 0.060
  7. Novel fate-tracing strategies show that hepatic stellate cells mediate fibrosis in vivo. Gastroenterology. 2014 Jun; 146(7):1823-5.
    View in: PubMed
    Score: 0.059
  8. Microbiome-obesity-liver cancer interaction: senescence of hepatic stellate cells and bile acids play new roles. Gastroenterology. 2014 Mar; 146(3):860-1.
    View in: PubMed
    Score: 0.058
  9. Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. Hepatology. 2014 Feb; 59(2):483-95.
    View in: PubMed
    Score: 0.058
  10. Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 01; 302(11):G1310-21.
    View in: PubMed
    Score: 0.051
  11. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 2010 Jul; 139(1):323-34.e7.
    View in: PubMed
    Score: 0.044
  12. Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):844-9.
    View in: PubMed
    Score: 0.044
  13. CCR1 and CCR5 promote hepatic fibrosis in mice. J Clin Invest. 2009 Jul; 119(7):1858-70.
    View in: PubMed
    Score: 0.042
  14. Demonstration of cooperative contribution of MET- and EGFR-mediated STAT3 phosphorylation to liver regeneration by exogenous suppressor of cytokine signalings. J Hepatol. 2008 Feb; 48(2):237-45.
    View in: PubMed
    Score: 0.038
  15. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med. 2007 Nov; 13(11):1324-32.
    View in: PubMed
    Score: 0.038
  16. Single-cell and spatial omics in liver identify cell-cell communication regulators in aging and insulin resistance. Metabolism. 2026 Aug; 181:156630.
    View in: PubMed
    Score: 0.034
  17. Selective inhibition of long isoforms of phosphodiesterase 4D mitigates liver fibrosis in mouse models. J Clin Invest. 2026 01 02; 136(1).
    View in: PubMed
    Score: 0.033
  18. A Cyanobacteria-Derived RNA Aptamer Resensitizes Prostate Cancer to Hormone Therapy. Cancer Res. 2025 Jul 15; 85(14):2714-2725.
    View in: PubMed
    Score: 0.032
  19. Contribution of Toll-like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration. Hepatology. 2005 Mar; 41(3):443-50.
    View in: PubMed
    Score: 0.031
  20. A1AT dysregulation of metabolically stressed hepatocytes by Kupffer cells drives MASH and fibrosis. Exp Mol Med. 2025 Feb; 57(2):450-465.
    View in: PubMed
    Score: 0.031
  21. Suppression of intestinal Ticam1 ameliorated MASH via Akkermansia muciniphila QAA37749.1 mediated betaine transformation. Biochim Biophys Acta Mol Basis Dis. 2025 Jan; 1871(1):167571.
    View in: PubMed
    Score: 0.031
  22. The role of forkhead box M1-methionine adenosyltransferase 2?A/2B axis in liver inflammation and fibrosis. Nat Commun. 2024 Sep 27; 15(1):8388.
    View in: PubMed
    Score: 0.030
  23. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. 2021 06 14; 39(6):866-882.e11.
    View in: PubMed
    Score: 0.024
  24. Reciprocal Regulation Between Forkhead Box M1/NF-?B and Methionine Adenosyltransferase 1A Drives Liver Cancer. Hepatology. 2020 11; 72(5):1682-1700.
    View in: PubMed
    Score: 0.023
  25. Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling. Gut. 2019 12; 68(12):2214-2227.
    View in: PubMed
    Score: 0.021
  26. Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. Cancer Cell. 2018 06 11; 33(6):1061-1077.e6.
    View in: PubMed
    Score: 0.020
  27. Mechanisms of MAFG Dysregulation in Cholestatic Liver Injury and Development of Liver Cancer. Gastroenterology. 2018 08; 155(2):557-571.e14.
    View in: PubMed
    Score: 0.019
  28. LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis. Sci Rep. 2016 10 18; 6:35610.
    View in: PubMed
    Score: 0.018
  29. Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells. PLoS One. 2016; 11(3):e0150893.
    View in: PubMed
    Score: 0.017
  30. Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. 2015 Dec; 149(7):1784-93.
    View in: PubMed
    Score: 0.016
  31. Inhibition of type I natural killer T cells by retinoids or following sulfatide-mediated activation of type II natural killer T cells attenuates alcoholic liver disease in mice. Hepatology. 2015 Apr; 61(4):1357-69.
    View in: PubMed
    Score: 0.016
  32. Effect of weight loss on magnetic resonance imaging estimation of liver fat and volume in patients with nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2015 Mar; 13(3):561-568.e1.
    View in: PubMed
    Score: 0.015
  33. ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. Cancer Cell. 2014 Sep 08; 26(3):331-343.
    View in: PubMed
    Score: 0.015
  34. GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nat Commun. 2014 Jul 21; 5:4451.
    View in: PubMed
    Score: 0.015
  35. Nrf2 activation protects the liver from ischemia/reperfusion injury in mice. Ann Surg. 2014 Jul; 260(1):118-27.
    View in: PubMed
    Score: 0.015
  36. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metab. 2014 Jul 01; 20(1):133-44.
    View in: PubMed
    Score: 0.015
  37. Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis. Hepatology. 2014 Jul; 60(1):237-49.
    View in: PubMed
    Score: 0.015
  38. NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet. Cell Metab. 2014 Jan 07; 19(1):6-7.
    View in: PubMed
    Score: 0.014
  39. A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. J Hepatol. 2014 Apr; 60(4):782-91.
    View in: PubMed
    Score: 0.014
  40. Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes. Surgery. 2012 Nov; 152(5):869-78.
    View in: PubMed
    Score: 0.013
  41. Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol Ther. 2012 Jul; 36(1):22-9.
    View in: PubMed
    Score: 0.013
  42. L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin. J Biol Chem. 2011 Oct 07; 286(40):34800-8.
    View in: PubMed
    Score: 0.012
  43. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. FASEB J. 2011 Apr; 25(4):1133-44.
    View in: PubMed
    Score: 0.012
  44. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Hepatology. 2010 Oct; 52(4):1420-30.
    View in: PubMed
    Score: 0.012
  45. Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice. Hepatology. 2010 Jan; 51(1):237-45.
    View in: PubMed
    Score: 0.011
  46. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 2009 Oct; 137(4):1467-1477.e5.
    View in: PubMed
    Score: 0.011
  47. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology. 2008 Dec; 48(6):2016-26.
    View in: PubMed
    Score: 0.010
  48. Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis. Am J Physiol Gastrointest Liver Physiol. 2007 Sep; 293(3):G631-9.
    View in: PubMed
    Score: 0.009
  49. Role of innate immune response in liver regeneration. J Gastroenterol Hepatol. 2007 Jun; 22 Suppl 1:S57-8.
    View in: PubMed
    Score: 0.009
  50. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology. 2007 May; 132(5):1937-46.
    View in: PubMed
    Score: 0.009
  51. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology. 2006 Aug; 44(2):420-9.
    View in: PubMed
    Score: 0.009
  52. Blockage of HGF/c-Met system by gene therapy (adenovirus-mediated NK4 gene) suppresses hepatocellular carcinoma in mice. J Hepatol. 2006 Nov; 45(5):688-95.
    View in: PubMed
    Score: 0.009
  53. Gastric bypass surgery improves metabolic and hepatic abnormalities associated with nonalcoholic fatty liver disease. Gastroenterology. 2006 May; 130(6):1564-72.
    View in: PubMed
    Score: 0.008
  54. Toll-like receptor signaling in the liver. Gastroenterology. 2006 May; 130(6):1886-900.
    View in: PubMed
    Score: 0.008
  55. Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. J Biol Chem. 2006 Apr 14; 281(15):10431-8.
    View in: PubMed
    Score: 0.008
  56. Nuclear factor kappa B decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model. Hepatology. 2003 Aug; 38(2):335-44.
    View in: PubMed
    Score: 0.007
  57. Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice. Cancer Sci. 2003 Aug; 94(8):679-85.
    View in: PubMed
    Score: 0.007
  58. Association of seropositivity for antibody to Chlamydia-specific lipopolysaccharide and coronary artery disease in Japanese men. Jpn Circ J. 2001 Mar; 65(3):182-7.
    View in: PubMed
    Score: 0.006
  59. Antihypertensive effect of valyl-tyrosine, a short chain peptide derived from sardine muscle hydrolyzate, on mild hypertensive subjects. J Hum Hypertens. 2000 Aug; 14(8):519-23.
    View in: PubMed
    Score: 0.006
  60. Mononuclear odontoclast participation in tooth resorption: the distribution of nuclei in human odontoclasts. Anat Rec. 1997 12; 249(4):449-57.
    View in: PubMed
    Score: 0.005
  61. A case of liposarcoma originating in the chest wall. Nihon Geka Hokan. 1995 Nov 01; 64(6):131-8.
    View in: PubMed
    Score: 0.004
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.