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Juan Raphael Caldera, PhD

TitleClinical Assistant Professor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentBiomedical Science Ed.
Address1731 E. 120th Street
Los Angeles CA 90059
PhoneNot Available
FaxNot Available
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    Bibliographic
    selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Caldera JR, Dayo A, Wiederhold N, Yang S. Development and validation of next-generation sequencing-based clinical test for triazole resistance prediction in Aspergillus fumigatus. J Clin Microbiol. 2025 Aug 13; 63(8):e0029125. PMID: 40590562; PMCID: PMC12345187.
      Citations:    Fields:    Translation:HumansAnimals
    2. Caldera JR, Saleh T, Fuller T, Yang S, Nielsen-Saines K. Multi-Year Analysis of Respiratory Viral Dynamics Reveals Significance of Rhinovirus in Young Children with Severe Respiratory Illness. Infect Dis Rep. 2025 Apr 03; 17(2). PMID: 40277956; PMCID: PMC12026606.
      Citations:    
    3. Kaur I, Shaw B, Multani A, Pham C, Malhotra S, Smith E, Adachi K, Allyn P, Bango Z, Beaird OE, Caldera JR, Chandrasekaran S, Chan L, Cheema R, Daouk S, Deville J, Dong HV, Fan A, Garner O, Gaynor P, Gray H, Gorin A, Kalava S, Kanatani M, Karnaze A, Saleh T, Sharma Y, Stauber S, Vargas M, Veral M, Winston D, Yanagimoto-Ogawa L, Aldrovandi G, Nielsen-Saines K, Fuller T, Jackson N, Uslan D, Schaenman J, Vijayan T, Sakona A, Yang S. Real-world clinical impact of plasma cell-free DNA metagenomic next-generation sequencing assay. Infect Control Hosp Epidemiol. 2025 Jan 30; 1-8. PMID: 39881594; PMCID: PMC12034450.
      Citations: 3     Fields:    
    4. Tsai CM, Hajam IA, Caldera JR, Chiang AW, Gonzalez C, Du X, Choudhruy B, Li H, Suzuki E, Askarian F, Clark T, Lin B, Wierzbicki IH, Riestra AM, Conrad DJ, Gonzalez DJ, Nizet V, Lewis NE, Liu GY. Pathobiont-driven antibody sialylation through IL-10 undermines vaccination. J Clin Invest. 2024 Dec 16; 134(24). PMID: 39680460; PMCID: PMC11645145.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    5. Hajam IA, Tsai CM, Gonzalez C, Caldera JR, L?zaro D?ez M, Du X, Aralar A, Lin B, Duong W, Liu GY. Pathobiont-induced suppressive immune imprints thwart T cell vaccine responses. Nat Commun. 2024 12 16; 15(1):10335. PMID: 39681568; PMCID: PMC11649901.
      Citations: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    6. Caldera JR, Shaw B, Uslan DZ, Yang S. Cluster of extensively drug-resistant Shigella sonnei carrying blaCTX-M-15 in Los Angeles, California, 2023 to 2024. Am J Infect Control. 2025 Apr; 53(4):524-526. PMID: 39667596.
      Citations: 1     Fields:    Translation:HumansCells
    7. Preston RC, Caldera JR, Gray HK, Lam JC. Getting to the Root of Dental Pain-a Hard Palate Ulcer. Clin Infect Dis. 2024 07 19; 79(1):237-239. PMID: 39028878.
      Citations:    Fields:    Translation:Humans
    8. Caldera JR, Anikst V, Gray H, Tsan A, Sono R, Yang S. Performance Evaluation of a Commercial Automated Library Preparation System for Clinical Microbial Whole-Genome Sequencing Assays. J Mol Diagn. 2024 Aug; 26(8):719-726. PMID: 38851385.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Caldera JR, Tsai CM, Trieu D, Gonzalez C, Hajam IA, Du X, Lin B, Liu GY. The characteristics of pre-existing humoral imprint determine efficacy of S.?aureus vaccines and support alternative vaccine approaches. Cell Rep Med. 2024 01 16; 5(1):101360. PMID: 38232694; PMCID: PMC10829788.
      Citations: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    10. Hajam IA, Katiki M, McNally R, L?zaro-D?ez M, Kolar S, Chatterjee A, Gonzalez C, Paulchakrabarti M, Choudhury B, Caldera JR, Desmond T, Tsai CM, Du X, Li H, Murali R, Liu GY. Functional divergence of a bacterial enzyme promotes healthy or acneic skin. Nat Commun. 2023 12 05; 14(1):8061. PMID: 38052825; PMCID: PMC10697930.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    11. Caldera JR, Gray HK, Garner OB, Yang S. FDA trial regulation of laboratory developed tests (LDTs): An academic medical center's experience with Mpox in-house testing. J Clin Virol. 2023 12; 169:105611. PMID: 37866092.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    12. Gray HK, Bisht A, Caldera JR, Fossas Braegger NM, Cambou MC, Sakona AN, Beaird OE, Uslan DZ, Walton SC, Yang S. Nosocomial infections by diverse carbapenemase-producing Aeromonas hydrophila associated with combination of plumbing issues and heat waves. Am J Infect Control. 2024 03; 52(3):337-343. PMID: 37778710.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    13. von Bredow B, Caldera JR, Cer?n S, Chan JL, Gray HK, Garner OB, Yang S. Clinical next-generation sequencing assay combining full-length gene amplification and shotgun sequencing for the detection of CMV drug resistance mutations. J Clin Virol. 2023 08; 165:105520. PMID: 37336174.
      Citations: 4     Fields:    Translation:HumansCells
    14. Caldera JR, Yang S, Uslan DZ. Extensively Drug-Resistant Shigella flexneri 2a, California, USA, 2022. Emerg Infect Dis. 2023 07; 29(7):1473-1475. PMID: 37204919; PMCID: PMC10310382.
      Citations: 1     Fields:    Translation:HumansCells
    15. Prabaker KK, de St Maurice A, Uslan DZ, Yen GC, Manavi S, Gray HK, Caldera JR, Chan JL, Garner OB, Yang S. Case Report: Symptomatic Herpes Simplex Virus Type 2 and Monkeypox Coinfection in an Adult Male. Am J Trop Med Hyg. 2022 12 14; 107(6):1258-1260. PMID: 36375467; PMCID: PMC9768272.
      Citations: 3     Fields:    Translation:HumansCells
    16. Tsai CM, Caldera JR, Hajam IA, Chiang AWT, Tsai CH, Li H, D?ez ML, Gonzalez C, Trieu D, Martins GA, Underhill DM, Arditi M, Lewis NE, Liu GY. Non-protective immune imprint underlies failure of Staphylococcus aureus IsdB vaccine. Cell Host Microbe. 2022 08 10; 30(8):1163-1172.e6. PMID: 35803276; PMCID: PMC9378590.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    17. Tsai CM, Hajam IA, Caldera JR, Liu GY. Integrating complex host-pathogen immune environments into S.?aureus vaccine studies. Cell Chem Biol. 2022 05 19; 29(5):730-740. PMID: 35594849; PMCID: PMC9179946.
      Citations: 9     Fields:    Translation:AnimalsCells
    18. Ha CWY, Martin A, Sepich-Poore GD, Shi B, Wang Y, Gouin K, Humphrey G, Sanders K, Ratnayake Y, Chan KSL, Hendrick G, Caldera JR, Arias C, Moskowitz JE, Ho Sui SJ, Yang S, Underhill D, Brady MJ, Knott S, Kaihara K, Steinbaugh MJ, Li H, McGovern DPB, Knight R, Fleshner P, Devkota S. Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans. Cell. 2020 10 29; 183(3):666-683.e17. PMID: 32991841; PMCID: PMC7521382.
      Citations: 200     Fields:    Translation:HumansAnimalsCells
    19. Wozniak JM, Mills RH, Olson J, Caldera JR, Sepich-Poore GD, Carrillo-Terrazas M, Tsai CM, Vargas F, Knight R, Dorrestein PC, Liu GY, Nizet V, Sakoulas G, Rose W, Gonzalez DJ. Mortality Risk Profiling of Staphylococcus aureus Bacteremia by Multi-omic Serum Analysis Reveals Early Predictive and Pathogenic Signatures. Cell. 2020 09 03; 182(5):1311-1327.e14. PMID: 32888495; PMCID: PMC7494005.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    20. Paterson MJ, Caldera JR, Nguyen C, Sharma P, Castro AM, Kolar SL, Tsai CM, Limon JJ, Becker CA, Martins GA, Liu GY, Underhill DM. Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy. PLoS Pathog. 2020 08; 16(8):e1008733. PMID: 32817694; PMCID: PMC7446838.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
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