"ORAI1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pore-forming subunit of calcium release activated calcium channels. It is activated by STROMAL INTERACTION MOLECULE 1 upon intracellular calcium depletion.
| Descriptor ID |
D000071740
|
| MeSH Number(s) |
D12.776.157.530.400.150.740.500 D12.776.543.550.450.150.740.500 D12.776.543.585.400.150.740.500
|
| Concept/Terms |
ORAI1 Protein- ORAI1 Protein
- Calcium Release-Activated Calcium Channel Protein 1
- Calcium Release Activated Calcium Channel Protein 1
- ORAI Calcium Release-Activated Calcium Modulator 1
- ORAI Calcium Release Activated Calcium Modulator 1
|
Below are MeSH descriptors whose meaning is more general than "ORAI1 Protein".
Below are MeSH descriptors whose meaning is more specific than "ORAI1 Protein".
This graph shows the total number of publications written about "ORAI1 Protein" by people in this website by year, and whether "ORAI1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "ORAI1 Protein" by people in Profiles.
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Deletion of myeloid-specific Orai1 calcium channel does not affect pancreatic tissue damage in experimental acute pancreatitis. Pancreatology. 2024 Jun; 24(4):528-537.
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Neutrophil-specific ORAI1 Calcium Channel Inhibition Reduces Pancreatitis-associated Acute Lung Injury. Function (Oxf). 2024; 5(1):zqad061.
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The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis. J Physiol. 2019 06; 597(12):3085-3105.