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Connection

Ekihiro Seki to Liver Cirrhosis

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This is a "connection" page, showing publications Ekihiro Seki has written about Liver Cirrhosis.
Ekihiro Seki
Connection Strength
12.008
Liver Cirrhosis
  1. Hyaluronan in liver fibrosis: basic mechanisms, clinical implications, and therapeutic targets. Hepatol Commun. 2023 04 01; 7(4).
    View in: PubMed
    Score: 0.778
  2. FAP: Not Just a Biomarker but Druggable Target in Liver Fibrosis. Cell Mol Gastroenterol Hepatol. 2023; 15(4):1018-1019.
    View in: PubMed
    Score: 0.769
  3. Experimental Workflow for Preclinical Studies of Human Antifibrotic Therapies. Methods Mol Biol. 2023; 2669:285-306.
    View in: PubMed
    Score: 0.767
  4. Hyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4. Exp Mol Med. 2022 06; 54(6):739-752.
    View in: PubMed
    Score: 0.737
  5. The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix. Food Chem Toxicol. 2020 Sep; 143:111556.
    View in: PubMed
    Score: 0.645
  6. Hepatic Stellate Cell-Macrophage Crosstalk in Liver Fibrosis and Carcinogenesis. Semin Liver Dis. 2020 Aug; 40(3):307-320.
    View in: PubMed
    Score: 0.634
  7. Hyaluronan synthase 2-mediated hyaluronan production mediates Notch1 activation and liver fibrosis. Sci Transl Med. 2019 06 12; 11(496).
    View in: PubMed
    Score: 0.599
  8. Chemokines and Chemokine Receptors in the Development of NAFLD. Adv Exp Med Biol. 2018; 1061:45-53.
    View in: PubMed
    Score: 0.542
  9. The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice. Int J Cancer. 2018 01 01; 142(1):81-91.
    View in: PubMed
    Score: 0.532
  10. Recent advancement of molecular mechanisms of liver fibrosis. J Hepatobiliary Pancreat Sci. 2015 Jul; 22(7):512-8.
    View in: PubMed
    Score: 0.449
  11. Hepatic inflammation and fibrosis: functional links and key pathways. Hepatology. 2015 Mar; 61(3):1066-79.
    View in: PubMed
    Score: 0.443
  12. Novel fate-tracing strategies show that hepatic stellate cells mediate fibrosis in vivo. Gastroenterology. 2014 Jun; 146(7):1823-5.
    View in: PubMed
    Score: 0.420
  13. Transcriptional repression of the transforming growth factor ? (TGF-?) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor ?B (NF-?B) p50 enhances TGF-? signaling in hepatic stellate cells. J Biol Chem. 2014 Mar 07; 289(10):7082-7091.
    View in: PubMed
    Score: 0.413
  14. Transforming growth factor-? signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1. Gastroenterology. 2013 May; 144(5):1042-1054.e4.
    View in: PubMed
    Score: 0.386
  15. Role of innate immunity and the microbiota in liver fibrosis: crosstalk between the liver and gut. J Physiol. 2012 Feb 01; 590(3):447-58.
    View in: PubMed
    Score: 0.355
  16. Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):844-9.
    View in: PubMed
    Score: 0.311
  17. CCR2 promotes hepatic fibrosis in mice. Hepatology. 2009 Jul; 50(1):185-97.
    View in: PubMed
    Score: 0.301
  18. A1AT dysregulation of metabolically stressed hepatocytes by Kupffer cells drives MASH and fibrosis. Exp Mol Med. 2025 Feb; 57(2):450-465.
    View in: PubMed
    Score: 0.222
  19. The role of forkhead box M1-methionine adenosyltransferase 2?A/2B axis in liver inflammation and fibrosis. Nat Commun. 2024 Sep 27; 15(1):8388.
    View in: PubMed
    Score: 0.216
  20. In?Vivo and In?Vitro Models to Study Liver Fibrosis: Mechanisms and Limitations. Cell Mol Gastroenterol Hepatol. 2023; 16(3):355-367.
    View in: PubMed
    Score: 0.197
  21. Targeting A-kinase anchoring protein 12 phosphorylation in hepatic stellate cells regulates liver injury and fibrosis in mouse models. Elife. 2022 10 04; 11.
    View in: PubMed
    Score: 0.188
  22. Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B. Can J Gastroenterol Hepatol. 2022; 2022:1048104.
    View in: PubMed
    Score: 0.185
  23. Glial cell line-derived neurotrophic factor (GDNF) mediates hepatic stellate cell activation via ALK5/Smad signalling. Gut. 2019 12; 68(12):2214-2227.
    View in: PubMed
    Score: 0.150
  24. MicroRNA-942 mediates hepatic stellate cell activation by regulating BAMBI expression in human liver fibrosis. Arch Toxicol. 2018 09; 92(9):2935-2946.
    View in: PubMed
    Score: 0.141
  25. Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells. PLoS One. 2016; 11(3):e0150893.
    View in: PubMed
    Score: 0.119
  26. Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. 2015 Dec; 149(7):1784-93.
    View in: PubMed
    Score: 0.115
  27. GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nat Commun. 2014 Jul 21; 5:4451.
    View in: PubMed
    Score: 0.107
  28. Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis. Hepatology. 2014 Jul; 60(1):237-49.
    View in: PubMed
    Score: 0.106
  29. Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice. Hepatology. 2013 Feb; 57(2):577-89.
    View in: PubMed
    Score: 0.096
  30. p38a inhibits liver fibrogenesis and consequent hepatocarcinogenesis by curtailing accumulation of reactive oxygen species. Cancer Res. 2013 Jan 01; 73(1):215-24.
    View in: PubMed
    Score: 0.096
  31. Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Aliment Pharmacol Ther. 2012 Jul; 36(1):22-9.
    View in: PubMed
    Score: 0.092
  32. Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2. Am J Physiol Gastrointest Liver Physiol. 2012 Jun 01; 302(11):G1310-21.
    View in: PubMed
    Score: 0.091
  33. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology. 2011 May; 53(5):1730-41.
    View in: PubMed
    Score: 0.085
  34. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Hepatology. 2010 Oct; 52(4):1420-30.
    View in: PubMed
    Score: 0.082
  35. Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology. 2009 Sep; 50(3):929-38.
    View in: PubMed
    Score: 0.076
  36. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integr Biol (Camb). 2009 Sep; 1(8-9):513-24.
    View in: PubMed
    Score: 0.076
  37. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology. 2008 Dec; 48(6):2016-26.
    View in: PubMed
    Score: 0.072
  38. Hepatic stellate cells secrete angiopoietin 1 that induces angiogenesis in liver fibrosis. Gastroenterology. 2008 Nov; 135(5):1729-38.
    View in: PubMed
    Score: 0.071
  39. Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Hepatology. 2007 Nov; 46(5):1443-52.
    View in: PubMed
    Score: 0.067
  40. Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis. Am J Physiol Gastrointest Liver Physiol. 2007 Sep; 293(3):G631-9.
    View in: PubMed
    Score: 0.066
  41. Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligation. Liver Int. 2006 Nov; 26(9):1138-47.
    View in: PubMed
    Score: 0.063
  42. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology. 2006 Aug; 44(2):420-9.
    View in: PubMed
    Score: 0.061
  43. Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1. J Hepatol. 2023 04; 78(4):805-819.
    View in: PubMed
    Score: 0.048
  44. Mutation of the 5'-untranslated region stem-loop structure inhibits a1(I) collagen expression in vivo. J Biol Chem. 2011 Mar 11; 286(10):8609-8619.
    View in: PubMed
    Score: 0.021
  45. Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice. Hepatology. 2010 Jan; 51(1):237-45.
    View in: PubMed
    Score: 0.019
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.