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Connection

Ekihiro Seki to Hepatocytes

This is a "connection" page, showing publications Ekihiro Seki has written about Hepatocytes.
Connection Strength

4.478
  1. The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice. Int J Cancer. 2018 01 01; 142(1):81-91.
    View in: PubMed
    Score: 0.542
  2. Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis by inhibiting RIPK1. Hepatology. 2016 07; 64(1):295-7.
    View in: PubMed
    Score: 0.495
  3. Reply: To PMID 23996730. Hepatology. 2014 Sep; 60(3):1114-5.
    View in: PubMed
    Score: 0.436
  4. TAK1 regulates hepatic cell survival and carcinogenesis. J Gastroenterol. 2014 Feb; 49(2):185-94.
    View in: PubMed
    Score: 0.420
  5. Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. Hepatology. 2014 Feb; 59(2):483-95.
    View in: PubMed
    Score: 0.418
  6. A1AT dysregulation of metabolically stressed hepatocytes by Kupffer cells drives MASH and fibrosis. Exp Mol Med. 2025 Feb; 57(2):450-465.
    View in: PubMed
    Score: 0.226
  7. The role of forkhead box M1-methionine adenosyltransferase 2?A/2B axis in liver inflammation and fibrosis. Nat Commun. 2024 Sep 27; 15(1):8388.
    View in: PubMed
    Score: 0.220
  8. Tumor Suppressor Down-Regulation Promotes Hepatocyte Proliferation: A New GANKster on the Block. Cell Mol Gastroenterol Hepatol. 2018; 6(3):345-346.
    View in: PubMed
    Score: 0.143
  9. LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis. Sci Rep. 2016 10 18; 6:35610.
    View in: PubMed
    Score: 0.127
  10. TLR2 and TLR9 contribute to alcohol-mediated liver injury through induction of CXCL1 and neutrophil infiltration. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 01; 309(1):G30-41.
    View in: PubMed
    Score: 0.115
  11. Hepatic inflammation and fibrosis: functional links and key pathways. Hepatology. 2015 Mar; 61(3):1066-79.
    View in: PubMed
    Score: 0.113
  12. Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-?B and JNK in hepatocytes. PLoS One. 2014; 9(12):e114071.
    View in: PubMed
    Score: 0.112
  13. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest. 2014 Aug; 124(8):3566-78.
    View in: PubMed
    Score: 0.108
  14. Transforming growth factor-? signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1. Gastroenterology. 2013 May; 144(5):1042-1054.e4.
    View in: PubMed
    Score: 0.098
  15. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol Clin Exp Res. 2011 Aug; 35(8):1509-18.
    View in: PubMed
    Score: 0.087
  16. Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):844-9.
    View in: PubMed
    Score: 0.079
  17. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology. 2008 Jul; 48(1):322-35.
    View in: PubMed
    Score: 0.071
  18. Demonstration of cooperative contribution of MET- and EGFR-mediated STAT3 phosphorylation to liver regeneration by exogenous suppressor of cytokine signalings. J Hepatol. 2008 Feb; 48(2):237-45.
    View in: PubMed
    Score: 0.068
  19. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology. 2007 May; 132(5):1937-46.
    View in: PubMed
    Score: 0.065
  20. Toll-like receptor signaling in the liver. Gastroenterology. 2006 May; 130(6):1886-900.
    View in: PubMed
    Score: 0.062
  21. Repeated hepatocyte injury promotes hepatic tumorigenesis in hepatitis C virus transgenic mice. Cancer Sci. 2003 Aug; 94(8):679-85.
    View in: PubMed
    Score: 0.051
  22. Depletion of mitochondrial methionine adenosyltransferase a1 triggers mitochondrial dysfunction in alcohol-associated liver disease. Nat Commun. 2022 01 28; 13(1):557.
    View in: PubMed
    Score: 0.046
  23. Hepatocyte TGF-? Signaling Inhibiting WAT Browning to Promote NAFLD and Obesity Is Associated With Let-7b-5p. Hepatol Commun. 2022 06; 6(6):1301-1321.
    View in: PubMed
    Score: 0.046
  24. Modeling alcohol-associated liver disease in a human Liver-Chip. Cell Rep. 2021 07 20; 36(3):109393.
    View in: PubMed
    Score: 0.044
  25. Reciprocal Regulation Between Forkhead Box M1/NF-?B and Methionine Adenosyltransferase 1A Drives Liver Cancer. Hepatology. 2020 11; 72(5):1682-1700.
    View in: PubMed
    Score: 0.042
  26. Ga12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 2018 12 03; 128(12):5587-5602.
    View in: PubMed
    Score: 0.037
  27. Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. Cancer Cell. 2018 06 11; 33(6):1061-1077.e6.
    View in: PubMed
    Score: 0.036
  28. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metab. 2014 Jul 01; 20(1):133-44.
    View in: PubMed
    Score: 0.027
  29. Liver epithelial cells proliferate under hypoxia and protect the liver from ischemic injury via expression of HIF-1 alpha target genes. Surgery. 2012 Nov; 152(5):869-78.
    View in: PubMed
    Score: 0.023
  30. L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin. J Biol Chem. 2011 Oct 07; 286(40):34800-8.
    View in: PubMed
    Score: 0.022
  31. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. FASEB J. 2011 Apr; 25(4):1133-44.
    View in: PubMed
    Score: 0.021
  32. Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice. Hepatology. 2010 Jan; 51(1):237-45.
    View in: PubMed
    Score: 0.020
  33. Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Hepatology. 2007 Nov; 46(5):1443-52.
    View in: PubMed
    Score: 0.017
  34. Fatty acid amide hydrolase determines anandamide-induced cell death in the liver. J Biol Chem. 2006 Apr 14; 281(15):10431-8.
    View in: PubMed
    Score: 0.015
  35. Contribution of CD1d-unrestricted hepatic DX5+ NKT cells to liver injury in Plasmodium berghei-parasitized erythrocyte-injected mice. Int Immunol. 2004 Jun; 16(6):787-98.
    View in: PubMed
    Score: 0.013
  36. Nuclear factor kappa B decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model. Hepatology. 2003 Aug; 38(2):335-44.
    View in: PubMed
    Score: 0.013
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.