"Trypsinogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The inactive proenzyme of trypsin secreted by the pancreas, activated in the duodenum via cleavage by enteropeptidase. (Stedman, 25th ed)
| Descriptor ID |
D014362
|
| MeSH Number(s) |
D08.622.885
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Trypsinogen".
Below are MeSH descriptors whose meaning is more specific than "Trypsinogen".
This graph shows the total number of publications written about "Trypsinogen" by people in this website by year, and whether "Trypsinogen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Trypsinogen" by people in Profiles.
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Protein kinase D: A therapeutic target in experimental alcoholic pancreatitis. Biochim Biophys Acta Mol Basis Dis. 2022 11 01; 1868(11):166486.
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Wild-Type Human PRSS2 and PRSS1R122H Cooperatively Initiate Spontaneous Hereditary Pancreatitis in Transgenic Mice. Gastroenterology. 2022 07; 163(1):313-315.e4.
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Trypsin activity governs increased susceptibility to pancreatitis in mice expressing human PRSS1R122H. J Clin Invest. 2020 01 02; 130(1):189-202.
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Impact of IVS8-(TG)m(T)n on IRT and sweat chloride levels in newborns identified by California CF newborn screening. J Cyst Fibros. 2012 May; 11(3):257-60.
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Protein kinase C delta-mediated processes in cholecystokinin-8-stimulated pancreatic acini. Pancreas. 2009 Nov; 38(8):930-5.
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Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest. 2009 Nov; 119(11):3340-55.
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Identification of CFTR, PRSS1, and SPINK1 mutations in 381 patients with pancreatitis. Pancreas. 2006 Oct; 33(3):221-7.
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Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology. 2004 Feb; 126(2):554-66.
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Differing effects of ethanol on in vitro stimulated pancreatic enzyme secretion in ethanol-fed and control rats. Pancreas. 1990; 5(1):27-36.