Pancreatic Stellate Cells
"Pancreatic Stellate Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Star-shaped, myofibroblast-like cells located in the periacinar, perivascular, and periductal regions of the EXOCRINE PANCREAS. They play a key role in the pathobiology of FIBROSIS; PANCREATITIS; and PANCREATIC CANCER.
| Descriptor ID |
D058954
|
| MeSH Number(s) |
A11.700
|
| Concept/Terms |
Pancreatic Stellate Cells- Pancreatic Stellate Cells
- Cell, Pancreatic Stellate
- Cells, Pancreatic Stellate
- Pancreatic Stellate Cell
- Stellate Cell, Pancreatic
- Stellate Cells, Pancreatic
|
Below are MeSH descriptors whose meaning is more general than "Pancreatic Stellate Cells".
Below are MeSH descriptors whose meaning is more specific than "Pancreatic Stellate Cells".
This graph shows the total number of publications written about "Pancreatic Stellate Cells" by people in this website by year, and whether "Pancreatic Stellate Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2015 | 1 | 2 | 3 |
| 2016 | 3 | 1 | 4 |
| 2019 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pancreatic Stellate Cells" by people in Profiles.
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Reactive Oxygen Species-Responsive Nanoparticles Toward Extracellular Matrix Normalization for Pancreatic Fibrosis Regression. Adv Sci (Weinh). 2024 05; 11(19):e2401254.
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Exosomal miR-140-3p and miR-143-3p from TGF-?1-treated pancreatic stellate cells target BCL2 mRNA to increase ?-cell apoptosis. Mol Cell Endocrinol. 2022 07 01; 551:111653.
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The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis. J Physiol. 2019 06; 597(12):3085-3105.
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Cadherin-11 Is a Cell Surface Marker Up-Regulated in Activated Pancreatic Stellate Cells and Is Involved in Pancreatic Cancer Cell Migration. Am J Pathol. 2017 Jan; 187(1):146-155.
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Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis. Gastroenterology. 2016 12; 151(6):1206-1217.
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Insulin promotes proliferation and fibrosing responses in activated pancreatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G675-G687.
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Phosphatidylinositol 3-Kinase: A Link Between Inflammation and Pancreatic Cancer. Pancreas. 2016 Jan; 45(1):21-31.
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Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. Sci Rep. 2015 Nov 16; 5:16759.
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Characterization of Mouse Models of Early Pancreatic Lesions Induced by Alcohol and Chronic Pancreatitis. Pancreas. 2015 Aug; 44(6):882-7.
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Alternatively activated macrophages promote pancreatic fibrosis in chronic pancreatitis. Nat Commun. 2015 May 18; 6:7158.