"Alkylating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly reactive chemicals that introduce alkyl radicals into biologically active molecules and thereby prevent their proper functioning. Many are used as antineoplastic agents, but most are very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. They have also been used as components in poison gases.
Descriptor ID |
D000477
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MeSH Number(s) |
D27.505.519.124 D27.888.569.035
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkylating Agents".
Below are MeSH descriptors whose meaning is more specific than "Alkylating Agents".
This graph shows the total number of publications written about "Alkylating Agents" by people in this website by year, and whether "Alkylating Agents" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2007 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Alkylating Agents" by people in Profiles.
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Observational Outcomes of Initial Trabeculectomy With Mitomycin C in Patients of African Descent vs Patients of European Descent: Five-Year Results. JAMA Ophthalmol. 2018 10 01; 136(10):1106-1113.
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Trabeculectomy and Combined Phacoemulsification-Trabeculectomy: Outcomes and Risk Factors for Failure in Primary Angle Closure Glaucoma. J Glaucoma. 2016 09; 25(9):763-9.
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Long-Term Bleb-Related Infections After Trabeculectomy: Incidence, Risk Factors, and Influence of Bleb Revision. Am J Ophthalmol. 2015 Jun; 159(6):1082-91.
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Long-term outcomes of resident- versus attending-performed primary trabeculectomy with mitomycin C in a United States residency program. Am J Ophthalmol. 2014 Jun; 157(6):1190-201.
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Severe loss of central vision in patients with advanced glaucoma undergoing trabeculectomy. Arch Ophthalmol. 2007 Aug; 125(8):1044-50.