"Sincalide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An octapeptide hormone present in the intestine and brain. When secreted from the gastric mucosa, it stimulates the release of bile from the gallbladder and digestive enzymes from the pancreas.
| Descriptor ID |
D012844
|
| MeSH Number(s) |
D06.472.317.152.700 D12.644.120.500
|
| Concept/Terms |
Sincalide- Sincalide
- CCK-OP
- OP-CCK
- H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
- Cholecystokinin Pancreozymin C-Terminal Octapeptide
- Cholecystokinin Pancreozymin C Terminal Octapeptide
- Syncalide
- CCK-8
- Cholecystokinin Octapeptide
SQ-19,844- SQ-19,844
- SQ 19,844
- SQ19,844
- SQ-19844
- SQ 19844
- SQ19844
|
Below are MeSH descriptors whose meaning is more general than "Sincalide".
Below are MeSH descriptors whose meaning is more specific than "Sincalide".
This graph shows the total number of publications written about "Sincalide" by people in this website by year, and whether "Sincalide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sincalide" by people in Profiles.
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Genetic inhibition of protein kinase Ce attenuates necrosis in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 01; 307(5):G550-63.
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Prosurvival Bcl-2 proteins stabilize pancreatic mitochondria and protect against necrosis in experimental pancreatitis. Exp Cell Res. 2009 Jul 01; 315(11):1975-89.
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Alcohol redirects CCK-mediated apical exocytosis to the acinar basolateral membrane in alcoholic pancreatitis. Traffic. 2007 May; 8(5):605-17.
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Ethanol sensitizes NF-kappaB activation in pancreatic acinar cells through effects on protein kinase C-epsilon. Am J Physiol Gastrointest Liver Physiol. 2006 Sep; 291(3):G432-8.
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Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology. 2004 Feb; 126(2):554-66.
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Animal and in vitro models of alcoholic pancreatitis: role of cholecystokinin. Pancreas. 2003 Nov; 27(4):297-300.
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Curcumin ameliorates ethanol and nonethanol experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2003 Jan; 284(1):G85-95.
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Ethanol diet increases the sensitivity of rats to pancreatitis induced by cholecystokinin octapeptide. Gastroenterology. 1999 Sep; 117(3):706-16.
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Early NF-kappaB activation is associated with hormone-induced pancreatitis. Am J Physiol. 1998 12; 275(6):G1402-14.
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The role of calcium in the regulation of protein synthesis in the exocrine pancreas. Pancreas. 1997 Mar; 14(2):133-41.