"Tauopathies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Neurodegenerative disorders involving deposition of abnormal tau protein isoforms (TAU PROTEINS) in neurons and glial cells in the brain. Pathological aggregations of tau proteins are associated with mutation of the tau gene on chromosome 17 in patients with ALZHEIMER DISEASE; DEMENTIA; PARKINSONIAN DISORDERS; progressive supranuclear palsy (SUPRANUCLEAR PALSY, PROGRESSIVE); and corticobasal degeneration.
| Descriptor ID |
D024801
|
| MeSH Number(s) |
C10.574.945
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tauopathies".
Below are MeSH descriptors whose meaning is more specific than "Tauopathies".
This graph shows the total number of publications written about "Tauopathies" by people in this website by year, and whether "Tauopathies" was a major or minor topic of these publications.
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Below are the most recent publications written about "Tauopathies" by people in Profiles.
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TBK1 interacts with tau and enhances neurodegeneration in tauopathy. J Biol Chem. 2021 Jan-Jun; 296:100760.
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Integrated analysis of the aging brain transcriptome and proteome in tauopathy. Mol Neurodegener. 2020 09 29; 15(1):56.
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Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies. Mol Psychiatry. 2018 06; 23(6):1521-1529.
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TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Curr Biol. 2006 Feb 07; 16(3):230-41.