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Michael G. Chez, MD

TitleClinical Professor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentPhysical Med & Rehab
Address1731 E. 120th Street
Los Angeles CA 90059
PhoneNot Available
FaxNot Available
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    Bibliographic
    selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yamamoto T, Chez M, Campos D, Lattanzi S, Matricardi S, Est?vez-Mar?a JC, D'Souza W, Trinka E, Cappucci S, Villanueva V. Effectiveness and safety of perampanel by concomitant antiseizure medications: Insights from the real-world PERMIT Extension study. Epilepsy Behav. 2025 Oct; 171:110651. PMID: 40857807.
      Citations:    Fields:    Translation:Humans
    2. Chez M, Klein P, Becker D, Peters JM, Carrazana E, Rabinowicz AL. Exploring proposed recommendations for immediate-use seizure medication: Treating both cluster and prolonged seizures with diazepam nasal spray. Epilepsia Open. 2025 Aug; 10(4):999-1008. PMID: 40347447; PMCID: PMC12362174.
      Citations: 1     Fields:    Translation:Humans
    3. Pina-Garza JE, Chez M, Cloyd J, Hirsch LJ, K?lvi?inen R, Klein P, Lagae L, Sankar R, Specchio N, Strzelczyk A, Toledo M, Trinka E. Outpatient management of prolonged seizures and seizure clusters to prevent progression to a higher-level emergency: Consensus recommendations of an expert working group. Epileptic Disord. 2024 Aug; 26(4):484-497. PMID: 38813941.
      Citations: 8     Fields:    Translation:Humans
    4. Wheless J, Wechsler RT, Penovich P, Segal E, Chez M, Coppola A, Datta A, D'Souza W, Najm I, Cappucci S, Sainz-Fuertes R, Villanueva V. Effectiveness, safety and tolerability of perampanel by age group when used to treat people with focal and generalized epilepsy in clinical practice: The PERMIT Extension study. Epilepsy Behav. 2023 Oct; 147:109369. PMID: 37619459.
      Citations: 4     Fields:    
    5. Flamini RJ, Comi AM, Bebin EM, Chez MG, Clark G, Devinsky O, Hussain SA, Lyons PD, Patel AD, Rosengard JL, Sahebkar F, Segal E, Seltzer L, Szaflarski JP, Weinstock A. Efficacy of cannabidiol in convulsive and nonconvulsive seizure types associated with treatment-resistant epilepsies in the Expanded Access Program. Epilepsia. 2023 08; 64(8):e156-e163. PMID: 37243404.
      Citations: 7     Fields:    Translation:Humans
    6. Sankar R, Chez M, Pina-Garza JE, Dixon-Salazar T, Flamini JR, Hyslop A, McGoldrick P, Millichap JJ, Resnick T, Rho JM, Wolf S. Proposed anti-seizure medication combinations with rufinamide in the treatment of Lennox-Gastaut syndrome: Narrative review and expert opinion. Seizure. 2023 Aug; 110:42-57. PMID: 37321047.
      Citations: 2     Fields:    Translation:Humans
    7. Wechsler RT, Wheless J, Zafar M, Huesmann GR, Lancman M, Segal E, Chez M, Aboumatar S, Patten A, Salah A, Malhotra M. PROVE: Retrospective, non-interventional, Phase IV study of perampanel in real-world clinical care of patients with epilepsy. Epilepsia Open. 2022 06; 7(2):293-305. PMID: 34942053; PMCID: PMC9159249.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    8. Simmons RL, Li H, Alten B, Santos MS, Jiang R, Paul B, Lalani SJ, Cortesi A, Parks K, Khandelwal N, Smith-Packard B, Phoong MA, Chez M, Fisher H, Scheuerle AE, Shinawi M, Hussain SA, Kavalali ET, Sherr EH, Voglmaier SM. Overcoming presynaptic effects of VAMP2 mutations with 4-aminopyridine treatment. Hum Mutat. 2020 11; 41(11):1999-2011. PMID: 32906212; PMCID: PMC10898792.
      Citations: 12     Fields:    Translation:HumansCells
    9. Chez M, Kile S, Lepage C, Parise C, Benabides B, Hankins A. A Randomized, Placebo-Controlled, Blinded, Crossover, Pilot Study of the Effects of Dextromethorphan/Quinidine for the Treatment of Neurobehavioral Symptoms in Adults with Autism. J Autism Dev Disord. 2020 May; 50(5):1532-1538. PMID: 30109474.
      Citations: 6     Fields:    Translation:Humans
    10. Salpietro V, Dixon CL, Guo H, Bello OD, Vandrovcova J, Efthymiou S, Maroofian R, Heimer G, Burglen L, Valence S, Torti E, Hacke M, Rankin J, Tariq H, Colin E, Procaccio V, Striano P, Mankad K, Lieb A, Chen S, Pisani L, Bettencourt C, M?nnikk? R, Manole A, Brusco A, Grosso E, Ferrero GB, Armstrong-Moron J, Gueden S, Bar-Yosef O, Tzadok M, Monaghan KG, Santiago-Sim T, Person RE, Cho MT, Willaert R, Yoo Y, Chae JH, Quan Y, Wu H, Wang T, Bernier RA, Xia K, Blesson A, Jain M, Motazacker MM, Jaeger B, Schneider AL, Boysen K, Muir AM, Myers CT, Gavrilova RH, Gunderson L, Schultz-Rogers L, Klee EW, Dyment D, Osmond M, Parellada M, Llorente C, Gonzalez-Pe?as J, Carracedo A, Van Haeringen A, Ruivenkamp C, Nava C, Heron D, Nardello R, Iacomino M, Minetti C, Skabar A, Fabretto A, SYNAPS Study Group, Raspall-Chaure M, Chez M, Tsai A, Fassi E, Shinawi M, Constantino JN, De Zorzi R, Fortuna S, Kok F, Keren B, Bonneau D, Choi M, Benzeev B, Zara F, Mefford HC, Scheffer IE, Clayton-Smith J, Macaya A, Rothman JE, Eichler EE, Kullmann DM, Houlden H. AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders. Nat Commun. 2019 07 12; 10(1):3094. PMID: 31300657; PMCID: PMC6626132.
      Citations: 132     Fields:    Translation:Humans
    11. Laux LC, Bebin EM, Checketts D, Chez M, Flamini R, Marsh ED, Miller I, Nichol K, Park Y, Segal E, Seltzer L, Szaflarski JP, Thiele EA, Weinstock A, CBD EAP study group. Long-term safety and efficacy of cannabidiol in children and adults with treatment resistant Lennox-Gastaut syndrome or Dravet syndrome: Expanded access program results. Epilepsy Res. 2019 08; 154:13-20. PMID: 31022635.
      Citations: 69     Fields:    Translation:HumansCTClinical Trials
    12. Parker KJ, Garner JP, Oztan O, Tarara ER, Li J, Sclafani V, Del Rosso LA, Chun K, Berquist SW, Chez MG, Partap S, Hardan AY, Sherr EH, Capitanio JP. Arginine vasopressin in cerebrospinal fluid is a marker of sociality in nonhuman primates. Sci Transl Med. 2018 05 02; 10(439). PMID: 29720452; PMCID: PMC6714978.
      Citations: 36     Fields:    Translation:AnimalsCells
    13. Chez M, Lepage C, Parise C, Dang-Chu A, Hankins A, Carroll M. Safety and Observations from a Placebo-Controlled, Crossover Study to Assess Use of Autologous Umbilical Cord Blood Stem Cells to Improve Symptoms in Children with Autism. Stem Cells Transl Med. 2018 04; 7(4):333-341. PMID: 29405603; PMCID: PMC5866927.
      Citations: 30     Fields:    Translation:HumansCells
    14. Chez M, Low R, Parise C, Donnel T. Safety and observations in a pilot study of lenalidomide for treatment in autism. Autism Res Treat. 2012; 2012:291601. PMID: 22997574; PMCID: PMC3446644.
      Citations: 6     
    15. Chez MG, Guido-Estrada N. Immune therapy in autism: historical experience and future directions with immunomodulatory therapy. Neurotherapeutics. 2010 Jul; 7(3):293-301. PMID: 20643382; PMCID: PMC5084233.
      Citations: 18     Fields:    Translation:HumansAnimals
    16. Henney HR, Chez M. Pediatric safety of tizanidine: clinical adverse event database and retrospective chart assessment. Paediatr Drugs. 2009; 11(6):397-406. PMID: 19877725.
      Citations: 6     Fields:    Translation:Humans
    17. Chez MG, Dowling T, Patel PB, Khanna P, Kominsky M. Elevation of tumor necrosis factor-alpha in cerebrospinal fluid of autistic children. Pediatr Neurol. 2007 Jun; 36(6):361-5. PMID: 17560496.
      Citations: 144     Fields:    Translation:Humans
    18. Chez MG, Burton Q, Dowling T, Chang M, Khanna P, Kramer C. Memantine as adjunctive therapy in children diagnosed with autistic spectrum disorders: an observation of initial clinical response and maintenance tolerability. J Child Neurol. 2007 May; 22(5):574-9. PMID: 17690064.
      Citations: 97     Fields:    Translation:HumansCTClinical Trials
    19. Chez MG, Chang M, Krasne V, Coughlan C, Kominsky M, Schwartz A. Frequency of epileptiform EEG abnormalities in a sequential screening of autistic patients with no known clinical epilepsy from 1996 to 2005. Epilepsy Behav. 2006 Feb; 8(1):267-71. PMID: 16403678.
      Citations: 74     Fields:    Translation:Humans
    20. Connolly AM, Chez M, Streif EM, Keeling RM, Golumbek PT, Kwon JM, Riviello JJ, Robinson RG, Neuman RJ, Deuel RM. Brain-derived neurotrophic factor and autoantibodies to neural antigens in sera of children with autistic spectrum disorders, Landau-Kleffner syndrome, and epilepsy. Biol Psychiatry. 2006 Feb 15; 59(4):354-63. PMID: 16181614.
      Citations: 91     Fields:    Translation:HumansCells
    21. Chez MG, Chin K, Hung PC. Immunizations, immunology, and autism. Semin Pediatr Neurol. 2004 Sep; 11(3):214-7. PMID: 15575416.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    22. Chez MG, Memon S, Hung PC. Neurologic treatment strategies in autism: an overview of medical intervention strategies. Semin Pediatr Neurol. 2004 Sep; 11(3):229-35. PMID: 15575419.
      Citations: 2     Fields:    Translation:Humans
    23. Chez MG, Buchanan T, Aimonovitch M, Mrazek S, Krasne V, Langburt W, Memon S. Frequency of EEG abnormalities in age-matched siblings of autistic children with abnormal sleep EEG patterns. Epilepsy Behav. 2004 Apr; 5(2):159-62. PMID: 15123015.
      Citations: 2     Fields:    Translation:Humans
    24. Chez MG, Aimonovitch M, Buchanan T, Mrazek S, Tremb RJ. Treating autistic spectrum disorders in children: utility of the cholinesterase inhibitor rivastigmine tartrate. J Child Neurol. 2004 Mar; 19(3):165-9. PMID: 15119476.
      Citations: 27     Fields:    Translation:Humans
    25. Aman MG, Novotny S, Samango-Sprouse C, Lecavalier L, Leonard E, Gadow KD, King BH, Pearson DA, Gernsbacher MA, Chez M. Outcome measures for clinical drug trials in autism. CNS Spectr. 2004 Jan; 9(1):36-47. PMID: 14999174; PMCID: PMC4441220.
      Citations: 33     Fields:    Translation:Humans
    26. Chez MG, Buchanan CP, Aimonovitch MC, Becker M, Schaefer K, Black C, Komen J. Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorders. J Child Neurol. 2002 Nov; 17(11):833-7. PMID: 12585724.
      Citations: 66     Fields:    Translation:HumansCTClinical Trials
    27. Chez MG, Buchanan CP, Bagan BT, Hammer MS, McCarthy KS, Ovrutskaya I, Nowinski CV, Cohen ZS. Secretin and autism: a two-part clinical investigation. J Autism Dev Disord. 2000 Apr; 30(2):87-94. PMID: 10832772.
      Citations: 23     Fields:    Translation:HumansCTClinical Trials
    28. Sandler RH, Bolte ER, Chez MG, Schrift MJ. Relief of psychiatric symptoms in a patient with Crohn's disease after metronidazole therapy. Clin Infect Dis. 2000 Jan; 30(1):213-4. PMID: 10619762.
      Citations: 1     Fields:    Translation:Humans
    29. Lewine JD, Andrews R, Chez M, Patil AA, Devinsky O, Smith M, Kanner A, Davis JT, Funke M, Jones G, Chong B, Provencal S, Weisend M, Lee RR, Orrison WW. Magnetoencephalographic patterns of epileptiform activity in children with regressive autism spectrum disorders. Pediatrics. 1999 Sep; 104(3 Pt 1):405-18. PMID: 10469763.
      Citations: 55     Fields:    Translation:Humans
    30. Connolly AM, Chez MG, Pestronk A, Arnold ST, Mehta S, Deuel RK. Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders. J Pediatr. 1999 May; 134(5):607-13. PMID: 10228297.
      Citations: 59     Fields:    Translation:Humans
    31. Chez MG, Hammer MS, Loeffel M, Nowinski C, Bagan BT. Clinical experience of three pediatric and one adult case of spike-and-wave status epilepticus treated with injectable valproic acid. J Child Neurol. 1999 Apr; 14(4):239-42. PMID: 10334398.
      Citations: 4     Fields:    Translation:Humans
    32. Chez MG, Bourgeois BF, Pippenger CE, Knowles WD. Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice. Clin Neuropharmacol. 1994 Feb; 17(1):32-7. PMID: 8149357.
      Citations: 3     Fields:    Translation:Animals
    33. Pranzatelli MR, Kao PC, Tate ED, Chaves E, Chez M, Dobyns WB, Kang H, Rothner DA. Antibodies to ACTH in opsoclonus-myoclonus. Neuropediatrics. 1993 Jun; 24(3):131-3. PMID: 8395029.
      Citations: 1     Fields:    Translation:Humans
    34. Chez M, Sila CA, Ransohoff RM, Longworth DL, Weida C. Ibuprofen-induced meningitis: detection of intrathecal IgG synthesis and immune complexes. Neurology. 1989 Dec; 39(12):1578-80. PMID: 2586773.
      Citations: 6     Fields:    Translation:Humans
    35. Szombathy SP, Chez MG, Laxer RM. Acute septic arthritis due to Acremonium. J Rheumatol. 1988 Apr; 15(4):714-5. PMID: 3397984.
      Citations: 6     Fields:    Translation:HumansAnimals
    36. Chez MG, Peterson RG. Altered metabolic incorporation of fucose and leucine into PNS myelin of 25-week-old diabetic (C57BL/Ks [db/db]) mice: effects of untreated diabetes on nerve metabolism. Neurochem Res. 1983 Apr; 8(4):465-72. PMID: 6888648.
      Citations:    Fields:    Translation:AnimalsCells
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