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Ghoneum, Mamdooh

One or more keywords matched the following properties of Ghoneum, Mamdooh

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overview	Dr. Ghoneum is an internationally recognized immunologist who is an expert in the area of cancer immune therapy. He has published 90 articles and 130 abstracts, including 11 books in Japanese and in English related to cancer immunology. He holds 3 patents for inventing 3 biological response modifiers (BRMs) for the treatment of cancer. Dr. Ghoneum's contribution to immunotherapy is introducing and patenting several new non-toxic BRMs that activate different arms of the immune system such as NK, T, and dendritic cells and induce apoptosis of cancer cells. The most extensively studied of these BRMs is called arabinoxylan MGN-3. In the most recent human clinical trials, MGN-3 was demonstrated to enhance the anti-cancer activity of chemotherapy for the treatment of hepatocellular carcinoma (HCC). This is the first time that a natural BRM was shown to be effective for the treatment of HCC. Dr. Ghoenum has received several international awards from: The American Cancer Society (1993), Japan Functional Food Research Association (JAFRA) (2002), and The Filipino-Chinese Medical Society (2005). In 2007 he was nominated for the annual $1 million prestigious Gotham Prize in Cancer Research for his novel discovery of using baker's yeast for the treatment of cancer. He created a video to educate the public about a new cancer therapy. He had special accelerated promotion. He has been awarded numerous research grants from NIH-MBRS and major research institutions in Japan. He has been a reviewer for the NIH Study Section Member. He has been an organizer for annual workshops between the Japanese Immunology Society and Charles Drew University since 1990. He is a member of several Scientific Societies, including the American Association for Cancer Research (AACR). Dr. Ghoneum's goal is to expand MGN-3 immunotherapy for the treatment of cancer in multiple clinical trials, and in addition to emphasize the importance of his novel approach for using yeast therapy for the treatment of cancer metastasis.

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overview

Dr. Ghoneum is an internationally recognized immunologist who is an expert in the area of cancer immune therapy. He has published 90 articles and 130 abstracts, including 11 books in Japanese and in English related to cancer immunology. He holds 3 patents for inventing 3 biological response modifiers (BRMs) for the treatment of cancer. Dr. Ghoneum's contribution to immunotherapy is introducing and patenting several new non-toxic BRMs that activate different arms of the immune system such as NK, T, and dendritic cells and induce apoptosis of cancer cells. The most extensively studied of these BRMs is called arabinoxylan MGN-3. In the most recent human clinical trials, MGN-3 was demonstrated to enhance the anti-cancer activity of chemotherapy for the treatment of hepatocellular carcinoma (HCC). This is the first time that a natural BRM was shown to be effective for the treatment of HCC. Dr. Ghoenum has received several international awards from: The American Cancer Society (1993), Japan Functional Food Research Association (JAFRA) (2002), and The Filipino-Chinese Medical Society (2005). In 2007 he was nominated for the annual $1 million prestigious Gotham Prize in Cancer Research for his novel discovery of using baker's yeast for the treatment of cancer. He created a video to educate the public about a new cancer therapy. He had special accelerated promotion. He has been awarded numerous research grants from NIH-MBRS and major research institutions in Japan. He has been a reviewer for the NIH Study Section Member. He has been an organizer for annual workshops between the Japanese Immunology Society and Charles Drew University since 1990. He is a member of several Scientific Societies, including the American Association for Cancer Research (AACR). Dr. Ghoneum's goal is to expand MGN-3 immunotherapy for the treatment of cancer in multiple clinical trials, and in addition to emphasize the importance of his novel approach for using yeast therapy for the treatment of cancer metastasis.

One or more keywords matched the following items that are connected to Ghoneum, Mamdooh

Item Type	Name
Academic Article	Phagocytosis of autologous lymphocytes by cervical preneoplastic and neoplastic cells.
Academic Article	Inhibition of SK cell activity in frogs by certain drugs and sugars.
Academic Article	Induction of apoptosis in breast cancer cells by Saccharomyces cerevisiae, the baker's yeast, in vitro.
Academic Article	Augmentation of macrophage phagocytosis by modified arabinoxylan rice bran (MGN-3/biobran).
Academic Article	Yeast therapy for the treatment of breast cancer: a nude mice model study.
Academic Article	Activation of human monocyte-derived dendritic cells in vitro by Thymax, a gross thymic extract.
Academic Article	Mgn-3/biobran enhances generation of cytotoxic CD8+ T cells via upregulation of dec-205 expression on dendritic cells.
Academic Article	Arabinoxylan rice bran (Biobran) suppresses the viremia level in patients with chronic HCV infection: A randomized trial.
Academic Article	Potential role of MRN-100, an iron-based compound, in upregulating production of cytokine IL-10 in human dendritic cells to promote an anti-inflammatory response in vitro.
Academic Article	Dietary baker's yeast sensitizes Ehrlich mammary adenocarcinoma to paclitaxel in mice bearing tumor.
Academic Article	In situ lymphophagocytosis by nonlymphoreticular neoplasms.
Academic Article	Natural cell-mediated cytotoxicity in vitiligo.
Academic Article	Natural killer cell activity in patients with carcinoma of the larynx and hypopharynx.
Academic Article	Phagocytosis of candida albicans by lymphatic tumour cells in vitro.
Academic Article	Synergistic role of arabinoxylan rice bran (MGN-3/Biobran) in S. cerevisiae-induced apoptosis of monolayer breast cancer MCF-7 cells.
Academic Article	S. cerevisiae induces apoptosis in human metastatic breast cancer cells by altering intracellular Ca2+ and the ratio of Bax and Bcl-2.
Academic Article	Baker's Yeast Sensitizes Metastatic Breast Cancer Cells to Paclitaxel In Vitro.
Academic Article	Effect of Nanodiamond and Nanoplatinum Liquid, DPV576, on Human Primary Keratinocytes.
Academic Article	Production of tumor necrosis factor-alpha and interferon-gamma from human peripheral blood lymphocytes by MGN-3, a modified arabinoxylan from rice bran, and its synergy with interleukin-2 in vitro.
Academic Article	Human placental extract ameliorates methotrexate-induced hepatotoxicity in rats via regulating antioxidative and anti-inflammatory responses.
Academic Article	Elevated apoptotic cell population in patients with chronic fatigue syndrome: the pivotal role of protein kinase RNA.
Academic Article	Anti-HIV activity in vitro of MGN-3, an activated arabinoxylane from rice bran.
Academic Article	Modified arabinoxylan rice bran (MGN-3/Biobran) sensitizes human T cell leukemia cells to death receptor (CD95)-induced apoptosis.
Academic Article	Modified arabinoxylan rice bran (MGN-3/Biobran) enhances yeast-induced apoptosis in human breast cancer cells in vitro.
Academic Article	Human squamous cell carcinoma of the tongue and colon undergoes apoptosis upon phagocytosis of Saccharomyces cerevisiae, the baker's yeast, in vitro.
Academic Article	Modified arabinoxylan rice bran (MGN3/Biobran) enhances intracellular killing of microbes by human phagocytic cells in vitro.
Academic Article	MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin.
Academic Article	Gross thymic extract, Thymax, induces apoptosis in human breast cancer cells in vitro through the mitochondrial pathway.
Academic Article	Nanodiamond and nanoplatinum liquid, DPV576, activates human monocyte-derived dendritic cells in vitro.
Academic Article	Arabinoxylan rice bran (MGN-3) enhances the effects of interventional therapies for the treatment of hepatocellular carcinoma: a three-year randomized clinical trial.
Academic Article	Synergistic apoptotic effect of arabinoxylan rice bran (MGN-3/Biobran) and curcumin (turmeric) on human multiple myeloma cell line U266 in vitro.
Academic Article	Selective induction of apoptosis in human gastric cancer cells by Lactobacillus kefiri (PFT), a novel kefir product.
Academic Article	A novel kefir product (PFT) activates dendritic cells to induce CD4+T and CD8+T cell responses in vitro.
Academic Article	Phagocytosis of Candida albicans by metastatic and non metastatic human breast cancer cell lines in vitro.
Academic Article	The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults' health-related quality of life: a randomized, double-blind, placebo-controlled clinical trial.
Academic Article	Apoptosis of breast cancer MCF-7 cells in vitro is induced specifically by yeast and not by fungal mycelia.
Academic Article	Susceptibility of the human LNCaP prostate cancer cells to the apoptotic effect of marina crystal minerals (MCM) in vitro.
Academic Article	Activation of human monocyte-derived dendritic cells in vitro by the biological response modifier arabinoxylan rice bran (MGN-3/Biobran).
Academic Article	Modified arabinoxylan from rice bran, MGN-3/biobran, sensitizes metastatic breast cancer cells to paclitaxel in vitro.
Academic Article	Apoptotic effect of a novel kefir product, PFT, on multidrug-resistant myeloid leukemia cells via a hole-piercing mechanism.
Academic Article	Marina crystal minerals (MCM) activate human dendritic cells to induce CD4+ and CD8+ T cell responses in vitro.
Academic Article	Inhibition of TRPV1 Channel Activity in Human CD4? T Cells by Nanodiamond and Nanoplatinum Liquid, DPV576.
Academic Article	Dietary Supplementation with Biobran/MGN-3 Increases Innate Resistance and Reduces the Incidence of Influenza-like Illnesses in Elderly Subjects: A Randomized, Double-Blind, Placebo-Controlled Pilot Clinical Trial.
Academic Article	T cell profiles in vitiligo.
Academic Article	Effect of methylcholanthrene on human natural killer cell cytotoxicity and lymphokine production in vitro.
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