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Yong Wu, MD, PhD

TitleAssociate Professor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentInternal Medicine
Address1731 E. 120th Street
Los Angeles CA 90059
Phone(323) 563-4885
FaxNot Available
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    Research
    research activities and funding
    SC1GM135050     (WU, YONG)Jun 1, 2020 - Apr 30, 2024
    NIH
    A novel metabolic reprograming strategy for the treatment of diabetes-associated breast cancer
    Role: Principal Investigator
    SC1CA200517     (WU, YONG)Jul 21, 2015 - Apr 30, 2020
    NIH
    Mechanisms behind hyperglycemia-associated breast cancer risk and progression
    Role: Principal Investigator

    Bibliographic
    selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wu Y, Vadgama JV. Advancing Cancer Research: Insights and Innovations in Pathogenesis and Targeted Therapies. J Pers Med. 2023 Feb 21; 13(3). PMID: 36983557; PMCID: PMC10051869.
      Citations:    
    2. Yang S, Jackson C, Karapetyan E, Dutta P, Kermah D, Wu Y, Wu Y, Schloss J, Vadgama JV. Roles of Protein Disulfide Isomerase in Breast Cancer. Cancers (Basel). 2022 Jan 31; 14(3). PMID: 35159012; PMCID: PMC8833603.
      Citations: 2     
    3. Hao Q, Wu Y, Wu Y, Wang P, Vadgama JV. Tumor-Derived Exosomes in Tumor-Induced Immune Suppression. Int J Mol Sci. 2022 Jan 27; 23(3). PMID: 35163380; PMCID: PMC8836190.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    4. Chung SS, Dutta P, Chard N, Wu Y, Chen QH, Chen G, Vadgama J. A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-?B inactivation in colorectal cancer cells. Oncotarget. 2019 Jul 16; 10(44):4516-4531. PMID: 31360301; PMCID: PMC6642039.
      Citations: 12     Fields:    
    5. Wu K, Yu X, Huang Z, Zhu D, Yi X, Wu YL, Hao Q, Kemp KT, Elshimali Y, Iyer R, Nguyen KT, Zheng S, Chen G, Chen QH, Wang G, Vadgama JV, Wu Y. Targeting of PP2Cd By a Small Molecule C23 Inhibits High Glucose-Induced Breast Cancer Progression In Vivo. Antioxid Redox Signal. 2019 06 10; 30(17):1983-1998. PMID: 29808718; PMCID: PMC6486665.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    6. Wu Y, Dong Y, Duan S, Zhu D, Deng L. Corrigendum to "Metabolic Syndrome, Inflammation, and Cancer". Mediators Inflamm. 2017; 2017:6598540. PMID: 29436533; PMCID: PMC5756907.
      Citations: 2     Fields:    
    7. Wu Y, Dong Y, Duan S, Zhu D, Deng L. Metabolic Syndrome, Inflammation, and Cancer. Mediators Inflamm. 2017; 2017:8259356. PMID: 29302133; PMCID: PMC5742519.
      Citations: 4     Fields:    Translation:HumansAnimals
    8. Chung SS, Wu Y, Okobi Q, Adekoya D, Atefi M, Clarke O, Dutta P, Vadgama JV. Proinflammatory Cytokines IL-6 and TNF-a Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells. Mediators Inflamm. 2017; 2017:5958429. PMID: 28676732; PMCID: PMC5476880.
      Citations: 32     Fields:    Translation:HumansCells
    9. Chung SS, Adekoya D, Enenmoh I, Clarke O, Wang P, Sarkyssian M, Wu Y, Vadgama JV. Salinomycin Abolished STAT3 and STAT1 Interactions and Reduced Telomerase Activity in Colorectal Cancer Cells. Anticancer Res. 2017 02; 37(2):445-453. PMID: 28179289; PMCID: PMC5425246.
      Citations: 12     Fields:    Translation:HumansCells
    10. Wu Y, Yu X, Yi X, Wu K, Dwabe S, Atefi M, Elshimali Y, Kemp KT, Bhat K, Haro J, Sarkissyan M, Vadgama JV. Aberrant Phosphorylation of SMAD4 Thr277-Mediated USP9x-SMAD4 Interaction by Free Fatty Acids Promotes Breast Cancer Metastasis. Cancer Res. 2017 03 15; 77(6):1383-1394. PMID: 28115363; PMCID: PMC5354968.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    11. Wu Y, Dong Y, Atefi M, Liu Y, Elshimali Y, Vadgama JV. Lactate, a Neglected Factor for Diabetes and Cancer Interaction. Mediators Inflamm. 2016; 2016:6456018. PMID: 28077918; PMCID: PMC5203906.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    12. Wu Y, Liu Y, Dong Y, Vadgama J. Diabetes-associated dysregulated cytokines and cancer. Integr Cancer Sci Ther. 2016 Feb; 3(1):370-378. PMID: 29930868; PMCID: PMC6007890.
      Citations: 3     
    13. Wu Y, Sarkissyan M, Mcghee E, Lee S, Vadgama JV. Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing. Breast Cancer Res Treat. 2015 Jun; 151(3):529-39. PMID: 25975952; PMCID: PMC4668274.
      Citations: 23     Fields:    Translation:HumansCells
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