PAX8 Transcription Factor
"PAX8 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A paired box transcription factor that functions in the development of THYROCYTES and the control of thyroid-specific gene expression. Mutations in the PAX8 gene are associated with THYROID DYSGENESIS and THYROID NEOPLASMS.
| Descriptor ID |
D000072636
|
| MeSH Number(s) |
D12.776.260.645.906 D12.776.930.700.906
|
| Concept/Terms |
PAX8 Transcription Factor- PAX8 Transcription Factor
- Transcription Factor, PAX8
- Paired-Box Protein, PAX8
- PAX8 Paired-Box Protein
- Paired Box Protein, PAX8
|
Below are MeSH descriptors whose meaning is more general than "PAX8 Transcription Factor".
Below are MeSH descriptors whose meaning is more specific than "PAX8 Transcription Factor".
This graph shows the total number of publications written about "PAX8 Transcription Factor" by people in this website by year, and whether "PAX8 Transcription Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "PAX8 Transcription Factor" by people in Profiles.
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Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52.
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A thyroid-specific far-upstream enhancer in the human sodium/iodide symporter gene requires Pax-8 binding and cyclic adenosine 3',5'-monophosphate response element-like sequence binding proteins for full activity and is differentially regulated in normal and thyroid cancer cells. Mol Endocrinol. 2002 Oct; 16(10):2266-82.
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Differential regulation of the human sodium/iodide symporter gene promoter in papillary thyroid carcinoma cell lines and normal thyroid cells. Endocrinology. 2001 Aug; 142(8):3369-79.