Thyroid Hormone Receptors alpha
"Thyroid Hormone Receptors alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRA gene (also known as NR1A1, THRA1, ERBA or ERBA1 gene) as several isoforms produced by alternative splicing.
| Descriptor ID |
D037021
|
| MeSH Number(s) |
D12.776.624.664.700.830.500 D12.776.826.850.500
|
| Concept/Terms |
Thyroid Hormone Receptors alpha- Thyroid Hormone Receptors alpha
- c-erbA Proteins
- c erbA Proteins
- Proto-Oncogene Proteins c-erbA
- Proto Oncogene Proteins c erbA
- c-erbA, Proto-Oncogene Proteins
- c-erb A Protein
- c erb A Protein
- c-erb A Proteins
- c erb A Proteins
- Receptors alpha, Thyroid Hormone
- c-erbA alpha
- c erbA alpha
- THRA Gene Products
- Gene Products, THRA
- ERBA1 Gene Products
- Gene Products, ERBA1
- NR1A1 Gene Products
- Gene Products, NR1A1
- c-erbA-1 Protein
- c erbA 1 Protein
- c-erbA alpha Protein
- c erbA alpha Protein
- c-erbA Protein
- c erbA Protein
- erbA Proto-Oncogene Products
- Proto-Oncogene Products, erbA
- erbA Proto Oncogene Products
|
Below are MeSH descriptors whose meaning is more general than "Thyroid Hormone Receptors alpha".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Hormone Receptors alpha".
This graph shows the total number of publications written about "Thyroid Hormone Receptors alpha" by people in this website by year, and whether "Thyroid Hormone Receptors alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Thyroid Hormone Receptors alpha" by people in Profiles.
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Thyroid hormone receptor alpha sumoylation modulates white adipose tissue stores. Sci Rep. 2021 12 16; 11(1):24105.
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Persistent COUP-TFII expression underlies the myopathy and impaired muscle regeneration observed in resistance to thyroid hormone-alpha. Sci Rep. 2021 02 25; 11(1):4601.
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Thyroid Hormone Receptor Alpha is Essential to Maintain the Satellite Cell Niche During Skeletal Muscle Injury and Sarcopenia of Aging. Thyroid. 2017 10; 27(10):1316-1322.
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Thyroid Hormone Receptor a Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15.
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Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508.
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A mutant thyroid hormone receptor alpha antagonizes peroxisome proliferator-activated receptor alpha signaling in vivo and impairs fatty acid oxidation. Endocrinology. 2007 Mar; 148(3):1206-17.
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Regulation of regional expression in rat brain PC2 by thyroid hormone/characterization of novel negative thyroid hormone response elements in the PC2 promoter. Am J Physiol Endocrinol Metab. 2005 Jan; 288(1):E236-45.
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A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice. J Biol Chem. 2003 Oct 03; 278(40):38913-20.