Thyroid Hormone Receptors beta
"Thyroid Hormone Receptors beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA transcription. They are encoded by the THRB gene (also known as NR1A2, THRB1, or ERBA2 gene) as several isoforms produced by alternative splicing. Mutations in the THRB gene cause THYROID HORMONE RESISTANCE SYNDROME.
| Descriptor ID |
D037042
|
| MeSH Number(s) |
D12.776.624.664.700.830.750 D12.776.826.850.750
|
| Concept/Terms |
Thyroid Hormone Receptors beta- Thyroid Hormone Receptors beta
- TR beta
- Thyroid Hormone Receptor beta
- ERBA2 Gene Products
- Gene Products, ERBA2
- NR1A2 Gene Products
- Gene Products, NR1A2
- Receptors beta, Thyroid Hormone
- c-erbA beta
- c erbA beta
- THRB Gene Products
- Gene Products, THRB
|
Below are MeSH descriptors whose meaning is more general than "Thyroid Hormone Receptors beta".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Hormone Receptors beta".
This graph shows the total number of publications written about "Thyroid Hormone Receptors beta" by people in this website by year, and whether "Thyroid Hormone Receptors beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thyroid Hormone Receptors beta" by people in Profiles.
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A Historical Reflection on Scientific Advances in Understanding Thyroid Hormone Action. Thyroid. 2023 10; 33(10):1140-1149.
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Thyroid hormone receptor ? sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16).
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Thyroid Hormone Receptor a Plays an Essential Role in Male Skeletal Muscle Myoblast Proliferation, Differentiation, and Response to Injury. Endocrinology. 2016 Jan; 157(1):4-15.
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A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T). J Clin Endocrinol Metab. 2015 Jul; 100(7):2511-4.
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Thyroid hormone receptor isoform-specific modification by small ubiquitin-like modifier (SUMO) modulates thyroid hormone-dependent gene regulation. J Biol Chem. 2012 Oct 19; 287(43):36499-508.
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Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis. Endocrinology. 2010 Jan; 151(1):432-40.
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Resistance to thyroid hormone in Hashimoto's thyroiditis. N Engl J Med. 2005 Feb 03; 352(5):517-8.
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Spared bone mass in rats treated with thyroid hormone receptor TR beta-selective compound GC-1. Am J Physiol Endocrinol Metab. 2003 Nov; 285(5):E1135-41.