"Thyroxine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
| Descriptor ID |
D013974
|
| MeSH Number(s) |
D06.472.931.812 D12.125.072.050.767
|
| Concept/Terms |
Thyroxine- Thyroxine
- T4 Thyroid Hormone
- Thyroid Hormone, T4
- Thyroxin
- O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
- L-3,5,3',5'-Tetraiodothyronine
- Levothyroxine
- L-Thyroxine
- L Thyroxine
- 3,5,3',5'-Tetraiodothyronine
- O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
Levothyroxin Deladande- Levothyroxin Deladande
- Deladande, Levothyroxin
- Levothyroxin Delalande
- Delalande, Levothyroxin
|
Below are MeSH descriptors whose meaning is more general than "Thyroxine".
Below are MeSH descriptors whose meaning is more specific than "Thyroxine".
This graph shows the total number of publications written about "Thyroxine" by people in this website by year, and whether "Thyroxine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Thyroxine" by people in Profiles.
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Thyroxine Treatment after Traumatic Brain Injury Suppresses Astrogliosis and Enhances Neuronal Recovery in Mice. Thyroid. 2025 09; 35(9):1083-1094.
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Reverse T3 in patients with hypothyroidism on different thyroid hormone replacement. PLoS One. 2025; 20(6):e0325046.
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Impact of Thyroid Status on Incident Kidney Dysfunction and Chronic Kidney Disease Progression in a Nationally Representative Cohort. Mayo Clin Proc. 2024 Jan; 99(1):39-56.
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Approach to the Patient With a Suppressed TSH. J Clin Endocrinol Metab. 2023 01 17; 108(2):472-482.
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Thyroid Gene Mutations in Pregnant and Breastfeeding Women Diagnosed With Transient Congenital Hypothyroidism: Implications for the Offspring's Health. Front Endocrinol (Lausanne). 2021; 12:679002.
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Thyroid hormone receptor ? sumoylation is required for thyrotropin regulation and thyroid hormone production. JCI Insight. 2021 08 23; 6(16).
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Thyroid hormone treatment activates protective pathways in both in?vivo and in?vitro models of neuronal injury. Mol Cell Endocrinol. 2017 09 05; 452:120-130.
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The debate over thyroid-function screening in pregnancy. N Engl J Med. 2012 Feb 09; 366(6):562-3.
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Management of hypothyroidism in pregnancy. Curr Opin Endocrinol Diabetes Obes. 2011 Oct; 18(5):304-9.
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Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288.