"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
| Descriptor ID |
D001253
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| MeSH Number(s) |
A08.637.200 A11.650.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in this website by year, and whether "Astrocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1999 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Dihydromyricetin improves social isolation-induced cognitive impairments and astrocytic changes in mice. Sci Rep. 2022 04 07; 12(1):5899.
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Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nat Med. 2020 05; 26(5):769-780.
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Novel role of the nociceptin system as a regulator of glutamate transporter expression in developing astrocytes. Glia. 2017 12; 65(12):2003-2023.
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Solvent microenvironments and copper binding alters the conformation and toxicity of a prion fragment. PLoS One. 2013; 8(12):e85160.
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Estradiol stimulates progesterone synthesis in hypothalamic astrocyte cultures. Endocrinology. 2007 Feb; 148(2):782-9.
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A membrane estrogen receptor mediates intracellular calcium release in astrocytes. Endocrinology. 2004 Aug; 145(8):3788-95.
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In vitro differences between astrocytes of control and wobbler mice spinal cord. Neurochem Res. 1999 Dec; 24(12):1535-41.
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Glucocorticoid regulation of in vitro astrocyte phagocytosis. Biocell. 1997 Apr; 21(1):83-9.
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Glucocorticoid receptors and actions in the spinal cord of the Wobbler mouse, a model for neurodegenerative diseases. J Steroid Biochem Mol Biol. 1997 Feb; 60(3-4):205-13.