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Richard J. Pietras, MD, PhD

TitleClinical Professor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentInternal Medicine
Address1731 E. 120th Street
Los Angeles CA 90059
PhoneNot Available
FaxNot Available
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    Research
    research activities and funding
    R21CA176337     (PIETRAS, RICHARD JOSEPH)Jun 1, 2013 - Mar 31, 2016
    NIH
    Development of New Therapeutics for Pancreatic Cancer Management
    Role: Principal Investigator
    U54CA143930     (PIETRAS, RICHARD JOSEPH)Sep 29, 2009 - Aug 31, 2021
    NIH
    (2/2) CDU/UCLA Cancer Center Partnership to Eliminate Cancer Health Disparities
    Role: Principal Investigator
    R01AG014785     (PIETRAS, RICHARD JOSEPH)Aug 15, 1997 - Jun 30, 2001
    NIH
    NEW ENDOCRINE THERAPY IN OLDER WOMEN WITH BREAST CANCER
    Role: Principal Investigator
    R29CA060835     (PIETRAS, RICHARD JOSEPH)Feb 1, 1995 - Jan 31, 2000
    NIH
    GROWTH FACTOR RECEPTOR DIRECTED THERAPY IN CANCER
    Role: Principal Investigator

    Bibliographic
    selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Boyapalli S, Alvarado GA, Avanthsa U, Nagi A, Manouchehri S, Testa K, Sumalbag J, Pietras RJ, Ben-Zur UM. A Case of Postural Orthostatic Tachycardia Syndrome in a 20-Year-Old Female Athlete: Review of Ivabradine Guidelines. JACC Case Rep. 2025 Jul 16; 30(19):104167. PMID: 40681233; PMCID: PMC12441330.
      Citations:    
    2. M?rquez-Garb?n DC, Yanes CD, Llarena G, Elashoff D, Hamilton N, Hardy M, Wadehra M, McCloskey SA, Pietras RJ. Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models. Nutrients. 2024 Jul 22; 16(14). PMID: 39064812; PMCID: PMC11279598.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    3. Wu Y, Tran T, Dwabe S, Sarkissyan M, Kim J, Nava M, Clayton S, Pietras R, Farias-Eisner R, Vadgama JV. Retraction Note: A83-01 inhibits TGF-?-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells. Breast Cancer Res Treat. 2024 Jul; 206(1):213. PMID: 38727890.
      Citations:    Fields:    
    4. Chan AM, Aguirre B, Liu L, Mah V, Balko JM, Tsui J, Wadehra NP, Moatamed NA, Khoshchehreh M, Dillard CM, Kiyohara M, Elshimali Y, Chang HR, Marquez-Garban D, Hamilton N, Pietras RJ, Gordon LK, Wadehra M. EMP2 Serves as a Functional Biomarker for Chemotherapy-Resistant Triple-Negative Breast Cancer. Cancers (Basel). 2024 Apr 12; 16(8). PMID: 38672563; PMCID: PMC11048488.
      Citations: 2     
    5. Hamilton N, Austin D, M?rquez-Garb?n D, Sanchez R, Chau B, Foos K, Wu Y, Vadgama J, Pietras R. Correction: Hamilton et al. Receptors for Insulin-Like Growth Factor-2 and Androgens as Therapeutic Targets in Triple-Negative Breast Cancer. Int. J. Mol. Sci. 2017, 18, 2305. Int J Mol Sci. 2024 Feb 23; 25(5). PMID: 38474325; PMCID: PMC10921924.
      Citations:    Fields:    
    6. Pegram M, Pietras R, Dang CT, Murthy R, Bachelot T, Janni W, Sharma P, Hamilton E, Saura C. Evolving perspectives on the treatment of HR+/HER2+ metastatic breast cancer. Ther Adv Med Oncol. 2023; 15:17588359231187201. PMID: 37576607; PMCID: PMC10422890.
      Citations: 8     
    7. Marquez-Garban DC, Morales Martinez M, Pietras RJ. Estradiol Induces Neutrophil Expansion to Promote TSC-Null Tumor Progression. Endocrinology. 2023 06 26; 164(8). PMID: 37289038; PMCID: PMC10292810.
      Citations:    Fields:    Translation:HumansCells
    8. Rangsrikitphoti P, Marquez-Garban DC, Pietras RJ, McGowan E, Boonyaratanakornkit V. Sex steroid hormones and DNA repair regulation: Implications on cancer treatment responses. J Steroid Biochem Mol Biol. 2023 03; 227:106230. PMID: 36450315.
      Citations: 3     Fields:    Translation:HumansCells
    9. Sterling C, M?rquez-Garb?n D, Vadgama JV, Pietras RJ. Squalamines in Blockade of Tumor-Associated Angiogenesis and Cancer Progression. Cancers (Basel). 2022 Oct 21; 14(20). PMID: 36291938; PMCID: PMC9601113.
      Citations: 2     
    10. Young PA, Márquez-Garbán DC, Noor ZS, Moatamed N, Elashoff D, Grogan T, Romero T, Sasano H, Saito R, Rausch R, Hamilton N, Dubinett SM, Garon EB, Pietras RJ. Investigation of Combination Treatment With an Aromatase Inhibitor Exemestane and Carboplatin-Based Therapy for Postmenopausal Women With Advanced NSCLC. JTO Clin Res Rep. 2021 Apr; 2(4):100150. PMID: 34590007; PMCID: PMC8474426.
      Citations: 5     
    11. Boonyaratanakornkit V, McGowan EM, Márquez-Garbán DC, Burton LP, Hamilton N, Pateetin P, Pietras RJ. Progesterone Receptor Signaling in the Breast Tumor Microenvironment. Adv Exp Med Biol. 2021; 1329:443-474. PMID: 34664251.
      Citations: 3     Fields:    Translation:HumansCells
    12. Su F, Gm A, Palgunachari MN, White CR, Stessman H, Wu Y, Vadgama J, Pietras R, Nguyen D, Reddy ST, Farias-Eisner R. Bovine HDL and Dual Domain HDL-Mimetic Peptides Inhibit Tumor Development in Mice. J Cancer Res Ther Oncol. 2020; 8(1). PMID: 32462055; PMCID: PMC7252215.
      Citations: 5     
    13. Márquez-Garbán DC, Deng G, Comin-Anduix B, Garcia AJ, Xing Y, Chen HW, Cheung-Lau G, Hamilton N, Jung ME, Pietras RJ. Antiestrogens in combination with immune checkpoint inhibitors in breast cancer immunotherapy. J Steroid Biochem Mol Biol. 2019 10; 193:105415. PMID: 31226312; PMCID: PMC6903431.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    14. Márquez-Garbán DC, Gorrín-Rivas M, Chen HW, Sterling C, Elashoff D, Hamilton N, Pietras RJ. Squalamine blocks tumor-associated angiogenesis and growth of human breast cancer cells with or without HER-2/neu overexpression. Cancer Lett. 2019 05 01; 449:66-75. PMID: 30771431; PMCID: PMC6598711.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    15. Young PA, Pietras RJ. Aromatase inhibitors combined with aspirin to prevent lung cancer in preclinical models. Transl Lung Cancer Res. 2018 Dec; 7(Suppl 4):S373-S376. PMID: 30705860; PMCID: PMC6328684.
      Citations: 2     
    16. Austin D, Hamilton N, Elshimali Y, Pietras R, Wu Y, Vadgama J. Estrogen receptor-beta is a potential target for triple negative breast cancer treatment. Oncotarget. 2018 Sep 21; 9(74):33912-33930. PMID: 30338035; PMCID: PMC6188058.
      Citations: 32     Fields:    
    17. Garon EB, Siegfried JM, Stabile LP, Young PA, Marquez-Garban DC, Park DJ, Patel R, Hu EH, Sadeghi S, Parikh RJ, Reckamp KL, Adams B, Elashoff RM, Elashoff D, Grogan T, Wang HJ, Dacic S, Brennan M, Valdes Y, Davenport S, Dubinett SM, Press MF, Slamon DJ, Pietras RJ. Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer. Lung Cancer. 2018 09; 123:91-98. PMID: 30089602; PMCID: PMC6118115.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    18. Boonyaratanakornkit V, Hamilton N, Márquez-Garbán DC, Pateetin P, McGowan EM, Pietras RJ. Extranuclear signaling by sex steroid receptors and clinical implications in breast cancer. Mol Cell Endocrinol. 2018 05 05; 466:51-72. PMID: 29146555; PMCID: PMC5878997.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    19. Hamilton N, Austin D, Márquez-Garbán D, Sanchez R, Chau B, Foos K, Wu Y, Vadgama J, Pietras R. Receptors for Insulin-Like Growth Factor-2 and Androgens as Therapeutic Targets in Triple-Negative Breast Cancer. Int J Mol Sci. 2017 Nov 02; 18(11). PMID: 29099049; PMCID: PMC5713274.
      Citations: 7     Fields:    Translation:HumansCells
    20. Yaghoubian JM, Adashek J, Yaghoubian-Yazi B, Nagar M, Toomari N, Pietras RJ, Ben-Zur UM. Incomplete Resolution of Deep Vein Thromboses during Rivaroxaban Therapy. Case Rep Cardiol. 2017; 2017:3628127. PMID: 28828188; PMCID: PMC5554577.
      Citations: 3     
    21. Deng X, Apple S, Zhao H, Song J, Lee M, Luo W, Wu X, Chung D, Pietras RJ, Chang HR. CD24 Expression and differential resistance to chemotherapy in triple-negative breast cancer. Oncotarget. 2017 Jun 13; 8(24):38294-38308. PMID: 28418843; PMCID: PMC5503533.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    22. Wu Y, Tran T, Dwabe S, Sarkissyan M, Kim J, Nava M, Clayton S, Pietras R, Farias-Eisner R, Vadgama JV. A83-01 inhibits TGF-ß-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells. Breast Cancer Res Treat. 2017 Jun; 163(3):449-460. PMID: 28337662; PMCID: PMC5427117.
      Citations: 33     Fields:    Translation:HumansCells
    23. Rankin J, Nagar M, Crosby J, Toomari N, Pietras R, Ben-Zur UM. Possible failure of novel direct-acting oral anticoagulants in management of pulmonary embolism: a case report. J Med Case Rep. 2016 Dec 03; 10(1):346. PMID: 27912791; PMCID: PMC5135742.
      Citations: 6     Fields:    Translation:Humans
    24. Kawprasertsri S, Pietras RJ, Marquez-Garban DC, Boonyaratanakornkit V. Progesterone receptor (PR) polyproline domain (PPD) mediates inhibition of epidermal growth factor receptor (EGFR) signaling in non-small cell lung cancer cells. Cancer Lett. 2016 May 01; 374(2):279-91. PMID: 26892043; PMCID: PMC5708136.
      Citations: 11     Fields:    Translation:HumansCells
    25. Mah V, Alavi M, Márquez-Garbán DC, Maresh EL, Kim SR, Horvath S, Bagryanova L, Huerta-Yepez S, Chia D, Pietras R, Goodglick L. Ribonucleotide reductase subunit M2 predicts survival in subgroups of patients with non-small cell lung carcinoma: effects of gender and smoking status. PLoS One. 2015; 10(5):e0127600. PMID: 26001082; PMCID: PMC4441434.
      Citations: 22     Fields:    Translation:Humans
    26. Hamilton N, Márquez-Garbán D, Mah V, Fernando G, Elshimali Y, Garbán H, Elashoff D, Vadgama J, Goodglick L, Pietras R. Biologic roles of estrogen receptor-ß and insulin-like growth factor-2 in triple-negative breast cancer. Biomed Res Int. 2015; 2015:925703. PMID: 25874233; PMCID: PMC4385615.
      Citations: 29     Fields:    Translation:HumansCells
    27. Hamilton N, Marquez-Garban D, Mah VH, Elshimali Y, Elashoff D, Garon EB, Vadgama J, Pietras R. Estrogen Receptor-ß and the Insulin-Like Growth Factor Axis as Potential Therapeutic Targets for Triple-Negative Breast Cancer. Crit Rev Oncog. 2015; 20(5-6):373-90. PMID: 27279236; PMCID: PMC5495464.
      Citations: 5     Fields:    Translation:Humans
    28. Garon EB, Pietras RJ, Finn RS, Kamranpour N, Pitts S, Márquez-Garbán DC, Desai AJ, Dering J, Hosmer W, von Euw EM, Dubinett SM, Slamon DJ. Antiestrogen fulvestrant enhances the antiproliferative effects of epidermal growth factor receptor inhibitors in human non-small-cell lung cancer. J Thorac Oncol. 2013 Mar; 8(3):270-8. PMID: 23399957; PMCID: PMC3573351.
      Citations: 32     Fields:    Translation:HumansCells
    29. Kazmi N, Márquez-Garbán DC, Aivazyan L, Hamilton N, Garon EB, Goodglick L, Pietras RJ. The role of estrogen, progesterone and aromatase in human non-small-cell lung cancer. Lung Cancer Manag. 2012 Dec; 1(4):259-272. PMID: 23650476; PMCID: PMC3643508.
      Citations: 17     
    30. Marquez-Garban DC, Mah V, Alavi M, Maresh EL, Chen HW, Bagryanova L, Horvath S, Chia D, Garon E, Goodglick L, Pietras RJ. Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids. 2011 Aug; 76(9):910-20. PMID: 21600232; PMCID: PMC3129425.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    31. Mah V, Marquez D, Alavi M, Maresh EL, Zhang L, Yoon N, Horvath S, Bagryanova L, Fishbein MC, Chia D, Pietras R, Goodglick L. Expression levels of estrogen receptor beta in conjunction with aromatase predict survival in non-small cell lung cancer. Lung Cancer. 2011 Nov; 74(2):318-25. PMID: 21511357; PMCID: PMC3175023.
      Citations: 36     Fields:    Translation:Humans
    32. Márquez-Garbán DC, Chen HW, Goodglick L, Fishbein MC, Pietras RJ. Targeting aromatase and estrogen signaling in human non-small cell lung cancer. Ann N Y Acad Sci. 2009 Feb; 1155:194-205. PMID: 19250205; PMCID: PMC2782616.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    33. Hurvitz SA, Pietras RJ. Rational management of endocrine resistance in breast cancer: a comprehensive review of estrogen receptor biology, treatment options, and future directions. Cancer. 2008 Nov 01; 113(9):2385-97. PMID: 18819158.
      Citations: 38     Fields:    Translation:Humans
    34. Márquez-Garbán DC, Pietras RJ. Estrogen-signaling pathways in lung cancer. Adv Exp Med Biol. 2008; 617:281-9. PMID: 18497051.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    35. Mah V, Seligson DB, Li A, Márquez DC, Wistuba II, Elshimali Y, Fishbein MC, Chia D, Pietras RJ, Goodglick L. Aromatase expression predicts survival in women with early-stage non small cell lung cancer. Cancer Res. 2007 Nov 01; 67(21):10484-90. PMID: 17974992; PMCID: PMC3581354.
      Citations: 67     Fields:    Translation:HumansAnimals
    36. Pietras RJ, Márquez-Garbán DC. Membrane-associated estrogen receptor signaling pathways in human cancers. Clin Cancer Res. 2007 Aug 15; 13(16):4672-6. PMID: 17699844.
      Citations: 71     Fields:    Translation:HumansCells
    37. Levin ER, Pietras RJ. Estrogen receptors outside the nucleus in breast cancer. Breast Cancer Res Treat. 2008 Apr; 108(3):351-61. PMID: 17592774.
      Citations: 70     Fields:    Translation:HumansCells
    38. Márquez-Garbán DC, Chen HW, Fishbein MC, Goodglick L, Pietras RJ. Estrogen receptor signaling pathways in human non-small cell lung cancer. Steroids. 2007 Feb; 72(2):135-43. PMID: 17276470; PMCID: PMC6662925.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    39. Pietras RJ. Biologic basis of sequential and combination therapies for hormone-responsive breast cancer. Oncologist. 2006 Jul-Aug; 11(7):704-17. PMID: 16880230.
      Citations: 18     Fields:    Translation:HumansCells
    40. Sartippour MR, Pietras R, Marquez-Garban DC, Chen HW, Heber D, Henning SM, Sartippour G, Zhang L, Lu M, Weinberg O, Rao JY, Brooks MN. The combination of green tea and tamoxifen is effective against breast cancer. Carcinogenesis. 2006 Dec; 27(12):2424-33. PMID: 16785249.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    41. Márquez DC, Chen HW, Curran EM, Welshons WV, Pietras RJ. Estrogen receptors in membrane lipid rafts and signal transduction in breast cancer. Mol Cell Endocrinol. 2006 Feb 26; 246(1-2):91-100. PMID: 16388889.
      Citations: 45     Fields:    Translation:HumansCells
    42. Pio BS, Park CK, Pietras R, Hsueh WA, Satyamurthy N, Pegram MD, Czernin J, Phelps ME, Silverman DH. Usefulness of 3'-[F-18]fluoro-3'-deoxythymidine with positron emission tomography in predicting breast cancer response to therapy. Mol Imaging Biol. 2006 Jan-Feb; 8(1):36-42. PMID: 16362149.
      Citations: 82     Fields:    Translation:Humans
    43. Weinberg OK, Marquez-Garban DC, Fishbein MC, Goodglick L, Garban HJ, Dubinett SM, Pietras RJ. Aromatase inhibitors in human lung cancer therapy. Cancer Res. 2005 Dec 15; 65(24):11287-91. PMID: 16357134.
      Citations: 82     Fields:    Translation:HumansAnimals
    44. Pietras RJ, Levin ER, Szego CM. Estrogen receptors and cell signaling. Science. 2005 Oct 07; 310(5745):51-3; author reply 51-3. PMID: 16210518.
      Citations: 16     Fields:    Translation:HumansCells
    45. Weinberg OK, Marquez-Garban DC, Pietras RJ. New approaches to reverse resistance to hormonal therapy in human breast cancer. Drug Resist Updat. 2005 Aug; 8(4):219-33. PMID: 16054421.
      Citations: 14     Fields:    Translation:Humans
    46. Pietras RJ. Overview of the FASEB 2004 summer research conference on steroid hormone receptors: integration of plasma membrane and nuclear-initiated signaling in hormone action. Steroids. 2005 May-Jun; 70(5-7):345-6. PMID: 15862815.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    47. Pietras RJ, Márquez DC, Chen HW, Tsai E, Weinberg O, Fishbein M. Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells. Steroids. 2005 May-Jun; 70(5-7):372-81. PMID: 15862820.
      Citations: 91     Fields:    Translation:HumansCells
    48. Pegram MD, Pietras R, Bajamonde A, Klein P, Fyfe G. Targeted therapy: wave of the future. J Clin Oncol. 2005 Mar 10; 23(8):1776-81. PMID: 15755985.
      Citations: 16     Fields:    Translation:Humans
    49. Pietras RJ, Weinberg OK. Antiangiogenic Steroids in Human Cancer Therapy. Evid Based Complement Alternat Med. 2005 03; 2(1):49-57. PMID: 15841278; PMCID: PMC1062159.
      Citations: 16     
    50. Garbán HJ, Márquez-Garbán DC, Pietras RJ, Ignarro LJ. Rapid nitric oxide-mediated S-nitrosylation of estrogen receptor: regulation of estrogen-dependent gene transcription. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2632-6. PMID: 15699347; PMCID: PMC548976.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    51. Dowsett M, Nicholson RI, Pietras RJ. Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance. Breast Cancer Res Treat. 2005; 93 Suppl 1:S11-8. PMID: 16247595.
      Citations: 26     Fields:    Translation:Humans
    52. Pegram MD, Konecny GE, O'Callaghan C, Beryt M, Pietras R, Slamon DJ. Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer. J Natl Cancer Inst. 2004 May 19; 96(10):739-49. PMID: 15150302.
      Citations: 145     Fields:    Translation:HumansAnimalsCells
    53. Pietras RJ. Interactions between estrogen and growth factor receptors in human breast cancers and the tumor-associated vasculature. Breast J. 2003 Sep-Oct; 9(5):361-73. PMID: 12968955.
      Citations: 29     Fields:    Translation:HumansCells
    54. Nemere I, Pietras RJ, Blackmore PF. Membrane receptors for steroid hormones: signal transduction and physiological significance. J Cell Biochem. 2003 Feb 15; 88(3):438-45. PMID: 12532320.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    55. Li D, Williams JI, Pietras RJ. Squalamine and cisplatin block angiogenesis and growth of human ovarian cancer cells with or without HER-2 gene overexpression. Oncogene. 2002 Apr 25; 21(18):2805-14. PMID: 11973639.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    56. Márquez DC, Lee J, Lin T, Pietras RJ. Epidermal growth factor receptor and tyrosine phosphorylation of estrogen receptor. Endocrine. 2001 Nov; 16(2):73-81. PMID: 11887937.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    57. Márquez DC, Pietras RJ. Membrane-associated binding sites for estrogen contribute to growth regulation of human breast cancer cells. Oncogene. 2001 Sep 06; 20(39):5420-30. PMID: 11571639.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    58. Pietras RJ, Nemere I, Szego CM. Steroid hormone receptors in target cell membranes. Endocrine. 2001 Apr; 14(3):417-27. PMID: 11444440.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    59. Pietras RJ, Szego CM. Cell membrane estrogen receptors resurface. Nat Med. 1999 Dec; 5(12):1330. PMID: 10581047.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    60. Aguilar Z, Akita RW, Finn RS, Ramos BL, Pegram MD, Kabbinavar FF, Pietras RJ, Pisacane P, Sliwkowski MX, Slamon DJ. Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells. Oncogene. 1999 Oct 28; 18(44):6050-62. PMID: 10557094.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    61. Pegram M, Hsu S, Lewis G, Pietras R, Beryt M, Sliwkowski M, Coombs D, Baly D, Kabbinavar F, Slamon D. Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers. Oncogene. 1999 Apr 01; 18(13):2241-51. PMID: 10327070.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    62. Pietras RJ, Poen JC, Gallardo D, Wongvipat PN, Lee HJ, Slamon DJ. Monoclonal antibody to HER-2/neureceptor modulates repair of radiation-induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene. Cancer Res. 1999 Mar 15; 59(6):1347-55. PMID: 10096569.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    63. Pietras RJ, Pegram MD, Finn RS, Maneval DA, Slamon DJ. Remission of human breast cancer xenografts on therapy with humanized monoclonal antibody to HER-2 receptor and DNA-reactive drugs. Oncogene. 1998 Oct 29; 17(17):2235-49. PMID: 9811454.
      Citations: 94     Fields:    Translation:HumansAnimalsCells
    64. Pegram MD, Finn RS, Arzoo K, Beryt M, Pietras RJ, Slamon DJ. The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene. 1997 Jul 31; 15(5):537-47. PMID: 9247307.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    65. Nguyen M, Tran C, Barsky S, Sun J, McBride W, Pegram M, Pietras R, Love S, Glaspy J. Thalidomide and chemotherapy combination. Int J Oncol. 1997 May; 10(5):965-9. PMID: 21533471.
      Citations: 3     Fields:    
    66. Pietras RJ, Arboleda J, Reese DM, Wongvipat N, Pegram MD, Ramos L, Gorman CM, Parker MG, Sliwkowski MX, Slamon DJ. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogene. 1995 Jun 15; 10(12):2435-46. PMID: 7784095.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    67. Pietras RJ, Fendly BM, Chazin VR, Pegram MD, Howell SB, Slamon DJ. Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene. 1994 Jul; 9(7):1829-38. PMID: 7911565.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    68. Pietras RJ, Szego CM. Cathepsin D in breast cancer. N Engl J Med. 1990 Jun 07; 322(23):1673-4. PMID: 2342529.
      Citations: 1     Fields:    Translation:Humans
    69. Szego CM, Pietras RJ. Subcellular distribution of oestrogen receptors. Nature. 1985 Sep 5-11; 317(6032):88-9. PMID: 4033791.
      Citations: 4     Fields:    Translation:AnimalsCells
    70. Pietras RJ, Szego CM. Specific internalization of estrogen and binding to nuclear matrix in isolated uterine cells. Biochem Biophys Res Commun. 1984 Aug 30; 123(1):84-91. PMID: 6477590.
      Citations: 8     Fields:    Translation:AnimalsCells
    71. Szego CM, Pietras RJ. Lysosomal functions in cellular activation: propagation of the actions of hormones and other effectors. Int Rev Cytol. 1984; 88:1-302. PMID: 6145684.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    72. Pietras RJ, Szego CM, Seeler BJ. Immunologic inhibition of estrogen binding and action in preputial-gland cells and their subcellular fractions. J Steroid Biochem. 1981 Aug; 14(8):679-91. PMID: 6272023.
      Citations: 1     Fields:    Translation:AnimalsCells
    73. Pietras RJ, Szego CM, Roberts JA, Seeler BJ. Lysosomal cathepsin B-like activity: mobilization in prereplicative and neoplastic epithelial cells. J Histochem Cytochem. 1981 Mar; 29(3A Suppl):440-50. PMID: 6972405.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    74. Pietras RJ, Szego CM. Partial purification and characterization of oestrogen receptors in subfractions of hepatocyte plasma membranes. Biochem J. 1980 Dec 01; 191(3):743-60. PMID: 7283971; PMCID: PMC1162274.
      Citations: 26     Fields:    Translation:AnimalsCells
    75. Pietras RJ, Szego CM. Estrogen receptors in uterine plasma membrane. J Steroid Biochem. 1979 Oct; 11(4):1471-83. PMID: 513766.
      Citations: 33     Fields:    Translation:AnimalsCells
    76. Pietras RJ, Szego CM. Estrogen-induced membrane alterations and growth associated with proteinase activity in endometrial cells. J Cell Biol. 1979 Jun; 81(3):649-63. PMID: 457777; PMCID: PMC2110385.
      Citations: 3     Fields:    Translation:AnimalsCells
    77. Pietras RJ, Szego CM, Mangan CE, Seeler BJ, Burtnett MM. Elevated serum cathepsin B1-like activity in women with neoplastic disease. Gynecol Oncol. 1979 Feb; 7(1):1-17. PMID: 374195.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    78. Pietras RJ, Szego CM. Metabolic and proliferative responses to estrogen by hepatocytes selected for plasma membrane binding-sites specific for estradiol-17beta. J Cell Physiol. 1979 Jan; 98(1):145-59. PMID: 368082.
      Citations: 10     Fields:    Translation:AnimalsCells
    79. Pietras RJ, Szego CM, Mangan CE, Seeler BJ, Burtnett MM, Orevi M. Elevated serum cathepsin B1 and vaginal pathology after prenatal DES exposure. Obstet Gynecol. 1978 Sep; 52(3):321-7. PMID: 703988.
      Citations: 4     Fields:    Translation:Humans
    80. Pietras RJ. Heritable membrane alterations and growth associated with enhanced leupeptin-sensitive proteinase activity in epithelial cells exposed to dibutylnitrosamine in vitro. Cancer Res. 1978 Apr; 38(4):1019-30. PMID: 305819.
      Citations: 1     Fields:    Translation:AnimalsCells
    81. Pietras RJ, Szego CM. Specific binding sites for oestrogen at the outer surfaces of isolated endometrial cells. Nature. 1977 Jan 06; 265(5589):69-72. PMID: 834244.
      Citations: 166     Fields:    Translation:AnimalsCells
    82. Pietras RJ, Naujokaitis PJ, Szego CM. Differential effects of vasopressin on the water, calcium and lysosomal enzyme contents of mitochondria-rich and lysosome-rich (granular) epithelial cells isolated from bullfrog urinary bladder. Mol Cell Endocrinol. 1976 Jan; 4(2):89-106. PMID: 1082422.
      Citations: 6     Fields:    Translation:AnimalsCells
    83. Pietras RJ, Szego CM. Surface modifications evoked by estradiol and diethylstilbestrol in isolated endometrial cells: evidence from lectin probes and extracellular release of lysosomal protease. Endocrinology. 1975 Dec; 97(6):1445-54. PMID: 1204572.
      Citations: 5     Fields:    Translation:AnimalsCells
    84. Pietras RJ, Seeler BJ, Szego CM. Influence of antidiuretic hormone on release of lysosomal hydrolase at mucosal surface of epithelial cells from urinary bladder. Nature. 1975 Oct 09; 257(5526):493-5. PMID: 1080837.
      Citations: 7     Fields:    Translation:AnimalsCells
    85. Pietras RJ, Szego CM. Steroid hormone-responsive, isolated endometrial cells. Endocrinology. 1975 Apr; 96(4):946-54. PMID: 1120483.
      Citations: 5     Fields:    Translation:Animals
    86. Pietras RJ, Szego CM. Endometrial cell calcium and oestrogen action. Nature. 1975 Jan 31; 253(5490):357-9. PMID: 1167402.
      Citations: 61     Fields:    Translation:Animals
    87. Pietras RJ, Naujokaitis PJ, Szego CM. Surface modifications evoked by antidiuretic hormone in isolated epithelial cells: evidence from lectin probes. J Supramol Struct. 1975; 3(5-6):391-400. PMID: 813065.
      Citations: 1     Fields:    Translation:AnimalsCells
    88. Pietras RJ, Wright EM. The membrane action of antidiuretic hormone (ADH) on toad urinary bladder. J Membr Biol. 1975; 22(2):107-23. PMID: 167172.
      Citations: 16     Fields:    Translation:AnimalsCells
    89. Pietras RJ, Moulton DG. Hormonal influences on odor detection in rats: changes associated with the estrous cycle, pseudopregnancy, ovariectomy, and administration of testosterone propionate. Physiol Behav. 1974 Mar; 12(3):475-91. PMID: 4820142.
      Citations: 21     Fields:    Translation:Animals
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