"Cathepsins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of lysosomal proteinases or endopeptidases found in aqueous extracts of a variety of animal tissues. They function optimally within an acidic pH range. The cathepsins occur as a variety of enzyme subtypes including SERINE PROTEASES; ASPARTIC PROTEINASES; and CYSTEINE PROTEASES.
| Descriptor ID |
D002403
|
| MeSH Number(s) |
D08.811.277.656.224
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cathepsins".
Below are MeSH descriptors whose meaning is more specific than "Cathepsins".
This graph shows the total number of publications written about "Cathepsins" by people in this website by year, and whether "Cathepsins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cathepsins" by people in Profiles.
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Stromal softness confines pancreatic cancer growth through lysosomal-cathepsin mediated YAP1 degradation. Cell Mol Life Sci. 2024 Oct 26; 81(1):442.
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Impaired autophagy and organellar dysfunction in pancreatitis. J Gastroenterol Hepatol. 2012 Mar; 27 Suppl 2:27-32.
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Impaired autophagic flux mediates acinar cell vacuole formation and trypsinogen activation in rodent models of acute pancreatitis. J Clin Invest. 2009 Nov; 119(11):3340-55.
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Peptide-degrading enzymatic activities in GH3 cells and rat anterior pituitary homogenates. Endocrinology. 1984 Apr; 114(4):1407-12.
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Lysosomal cathepsin B-like activity: mobilization in prereplicative and neoplastic epithelial cells. J Histochem Cytochem. 1981 Mar; 29(3A Suppl):440-50.
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Estrogen-induced membrane alterations and growth associated with proteinase activity in endometrial cells. J Cell Biol. 1979 Jun; 81(3):649-63.
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Elevated serum cathepsin B1-like activity in women with neoplastic disease. Gynecol Oncol. 1979 Feb; 7(1):1-17.
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Elevated serum cathepsin B1 and vaginal pathology after prenatal DES exposure. Obstet Gynecol. 1978 Sep; 52(3):321-7.
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Heritable membrane alterations and growth associated with enhanced leupeptin-sensitive proteinase activity in epithelial cells exposed to dibutylnitrosamine in vitro. Cancer Res. 1978 Apr; 38(4):1019-30.
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Differential effects of vasopressin on the water, calcium and lysosomal enzyme contents of mitochondria-rich and lysosome-rich (granular) epithelial cells isolated from bullfrog urinary bladder. Mol Cell Endocrinol. 1976 Jan; 4(2):89-106.