"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Descriptor ID |
D007328
|
MeSH Number(s) |
D06.472.699.587.200.500.625 D12.644.548.586.200.500.625
|
Concept/Terms |
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
|
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in this website by year, and whether "Insulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 2 | 0 | 2 |
1996 | 1 | 3 | 4 |
1997 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2000 | 1 | 1 | 2 |
2001 | 0 | 1 | 1 |
2002 | 1 | 1 | 2 |
2003 | 0 | 1 | 1 |
2004 | 3 | 0 | 3 |
2005 | 2 | 1 | 3 |
2006 | 1 | 2 | 3 |
2007 | 1 | 1 | 2 |
2008 | 1 | 1 | 2 |
2009 | 3 | 0 | 3 |
2010 | 1 | 1 | 2 |
2011 | 3 | 0 | 3 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2014 | 3 | 0 | 3 |
2015 | 1 | 2 | 3 |
2016 | 1 | 1 | 2 |
2017 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2019 | 2 | 0 | 2 |
2020 | 1 | 0 | 1 |
2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Insulin" by people in Profiles.
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A simplified straightforward protocol for the use of U-500 regular insulin. Diabetes Obes Metab. 2023 02; 25(2):634-636.
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Comment on Aleppo et al. The Effect of Discontinuing Continuous Monitoring in Adults With Type 2 Diabetes Treated With Basal Insulin. Diabetes Care 2021;44:2729-2737. Diabetes Care. 2022 04 01; 45(4):e84.
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Antidiabetic efficacy of Trifolium alexandrinum extracts hesperetin and quercetin in ameliorating carbohydrate metabolism and activating IR and AMPK signaling in the pancreatic tissues of diabetic rats. Biomed Pharmacother. 2022 May; 149:112838.
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Second-generation basal insulins to initiate insulin therapy in type 2 diabetes: A need for clinical evidence before incurring increased costs. Diabetes Obes Metab. 2020 05; 22(5):719-721.
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Review: Rapid-acting analogues do not differ from regular human insulin for mortality or HbA1c in type 2 diabetes. Ann Intern Med. 2019 04 16; 170(8):JC39.
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Delayed response to an injection of U-500 regular insulin is not rare. J Diabetes. 2019 Jul; 11(7):519-521.
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Intrauterine Growth Restriction Modifies the Accumbal Dopaminergic Response to Palatable Food Intake. Neuroscience. 2019 02 21; 400:184-195.
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Continuous Glucose Monitoring in Patients With Type 1 Diabetes Taking Insulin Injections. JAMA. 2017 01 24; 317(4):363-364.
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Maternal bisphenol A exposure alters rat offspring hepatic and skeletal muscle insulin signaling protein abundance. Am J Obstet Gynecol. 2017 03; 216(3):290.e1-290.e9.
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Metabolic effects of smoking cessation. Nat Rev Endocrinol. 2016 May; 12(5):299-308.