"Interleukin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by MONOCYTES; MACROPHAGES, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. Interleukin-1 is a general term refers to either of the two distinct proteins, INTERLEUKIN-1ALPHA and INTERLEUKIN-1BETA. The biological effects of IL-1 include the ability to replace macrophage requirements for T-cell activation.
Descriptor ID |
D007375
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MeSH Number(s) |
D12.644.276.374.465.010 D12.644.276.374.500.400 D12.776.467.374.465.010 D12.776.467.374.500.400 D23.529.374.465.131 D23.529.374.500.400
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Concept/Terms |
Interleukin-1- Interleukin-1
- Interleukin 1
- IL-1
- T Helper Factor
- Lymphocyte-Activating Factor
- Lymphocyte Activating Factor
- Macrophage Cell Factor
- Epidermal Cell Derived Thymocyte-Activating Factor
- Epidermal Cell Derived Thymocyte Activating Factor
- Interleukin I
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Below are MeSH descriptors whose meaning is more general than "Interleukin-1".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-1".
This graph shows the total number of publications written about "Interleukin-1" by people in this website by year, and whether "Interleukin-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 2 | 3 |
2001 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-1" by people in Profiles.
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Proteasome inhibitors protect the steatotic and non-steatotic liver graft against cold ischemia reperfusion injury. Exp Mol Pathol. 2013 Apr; 94(2):352-9.
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Roles of caspase-1 in Listeria infection in mice. Int Immunol. 2004 Feb; 16(2):335-43.
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Nuclear factor kappa B decoy oligodeoxynucleotides prevent endotoxin-induced fatal liver failure in a murine model. Hepatology. 2003 Aug; 38(2):335-44.
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Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta. J Immunol. 2001 Feb 15; 166(4):2651-7.
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In vitro differences between astrocytes of control and wobbler mice spinal cord. Neurochem Res. 1999 Dec; 24(12):1535-41.
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Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators. Circulation. 1999 Jun 22; 99(24):3103-9.
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Inflammatory cytokines and oxidized low density lipoproteins increase endothelial cell expression of membrane type 1-matrix metalloproteinase. J Biol Chem. 1999 Apr 23; 274(17):11924-9.
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Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message. J Clin Invest. 1991 May; 87(5):1763-72.
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Central administration of alpha-MSH antiserum augments fever in the rabbit. Am J Physiol. 1986 May; 250(5 Pt 2):R803-6.
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Fever-specific changes in central MSH and CRF concentrations. Am J Physiol. 1985 Jan; 248(1 Pt 2):R125-9.