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Connection

Ekihiro Seki to Mice, Knockout

This is a "connection" page, showing publications Ekihiro Seki has written about Mice, Knockout.
Connection Strength

2.101
  1. Metastatic tumor growth in steatotic liver is promoted by HAS2-mediated fibrotic tumor microenvironment. J Clin Invest. 2025 Feb 13; 135(7).
    View in: PubMed
    Score: 0.228
  2. Suppression of intestinal Ticam1 ameliorated MASH via Akkermansia muciniphila QAA37749.1 mediated betaine transformation. Biochim Biophys Acta Mol Basis Dis. 2025 Jan; 1871(1):167571.
    View in: PubMed
    Score: 0.224
  3. Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22. Proc Natl Acad Sci U S A. 2021 01 05; 118(1).
    View in: PubMed
    Score: 0.171
  4. Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria. J Biol Chem. 2019 08 16; 294(33):12359-12369.
    View in: PubMed
    Score: 0.154
  5. The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice. Int J Cancer. 2018 01 01; 142(1):81-91.
    View in: PubMed
    Score: 0.137
  6. Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis by inhibiting RIPK1. Hepatology. 2016 07; 64(1):295-7.
    View in: PubMed
    Score: 0.125
  7. TLR2 and TLR9 contribute to alcohol-mediated liver injury through induction of CXCL1 and neutrophil infiltration. Am J Physiol Gastrointest Liver Physiol. 2015 Jul 01; 309(1):G30-41.
    View in: PubMed
    Score: 0.116
  8. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest. 2014 Aug; 124(8):3566-78.
    View in: PubMed
    Score: 0.109
  9. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol Clin Exp Res. 2011 Aug; 35(8):1509-18.
    View in: PubMed
    Score: 0.087
  10. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nat Med. 2007 Nov; 13(11):1324-32.
    View in: PubMed
    Score: 0.069
  11. A1AT dysregulation of metabolically stressed hepatocytes by Kupffer cells drives MASH and fibrosis. Exp Mol Med. 2025 Feb; 57(2):450-465.
    View in: PubMed
    Score: 0.057
  12. The role of forkhead box M1-methionine adenosyltransferase 2?A/2B axis in liver inflammation and fibrosis. Nat Commun. 2024 Sep 27; 15(1):8388.
    View in: PubMed
    Score: 0.056
  13. Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice. J Immunol. 2002 Oct 01; 169(7):3863-8.
    View in: PubMed
    Score: 0.048
  14. Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts. J Clin Invest. 2021 06 01; 131(11).
    View in: PubMed
    Score: 0.044
  15. Lipopolysaccharide-induced IL-18 secretion from murine Kupffer cells independently of myeloid differentiation factor 88 that is critically involved in induction of production of IL-12 and IL-1beta. J Immunol. 2001 Feb 15; 166(4):2651-7.
    View in: PubMed
    Score: 0.043
  16. Reciprocal Regulation Between Forkhead Box M1/NF-?B and Methionine Adenosyltransferase 1A Drives Liver Cancer. Hepatology. 2020 11; 72(5):1682-1700.
    View in: PubMed
    Score: 0.042
  17. Ga12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 2018 12 03; 128(12):5587-5602.
    View in: PubMed
    Score: 0.037
  18. Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling. Cancer Cell. 2018 06 11; 33(6):1061-1077.e6.
    View in: PubMed
    Score: 0.036
  19. LPS-TLR4 Pathway Mediates Ductular Cell Expansion in Alcoholic Hepatitis. Sci Rep. 2016 10 18; 6:35610.
    View in: PubMed
    Score: 0.032
  20. Nrf2 activation protects the liver from ischemia/reperfusion injury in mice. Ann Surg. 2014 Jul; 260(1):118-27.
    View in: PubMed
    Score: 0.027
  21. Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. Cell Metab. 2014 Jul 01; 20(1):133-44.
    View in: PubMed
    Score: 0.027
  22. Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis. Hepatology. 2014 Jul; 60(1):237-49.
    View in: PubMed
    Score: 0.027
  23. A TLR2/S100A9/CXCL-2 signaling network is necessary for neutrophil recruitment in acute and chronic liver injury in the mouse. J Hepatol. 2014 Apr; 60(4):782-91.
    View in: PubMed
    Score: 0.026
  24. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91(phox) mediate hepatic fibrosis in mice. Hepatology. 2011 May; 53(5):1730-41.
    View in: PubMed
    Score: 0.022
  25. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Hepatology. 2010 Oct; 52(4):1420-30.
    View in: PubMed
    Score: 0.021
  26. Role of acid sphingomyelinase of Kupffer cells in cholestatic liver injury in mice. Hepatology. 2010 Jan; 51(1):237-45.
    View in: PubMed
    Score: 0.020
  27. Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology. 2009 Sep; 50(3):929-38.
    View in: PubMed
    Score: 0.020
  28. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 2009 Oct; 137(4):1467-1477.e5.
    View in: PubMed
    Score: 0.019
  29. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology. 2008 Dec; 48(6):2016-26.
    View in: PubMed
    Score: 0.019
  30. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology. 2006 Aug; 44(2):420-9.
    View in: PubMed
    Score: 0.016
  31. ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules. Genes Cells. 2004 Nov; 9(11):1055-67.
    View in: PubMed
    Score: 0.014
  32. Roles of caspase-1 in Listeria infection in mice. Int Immunol. 2004 Feb; 16(2):335-43.
    View in: PubMed
    Score: 0.013
  33. Plasmodium berghei infection in mice induces liver injury by an IL-12- and toll-like receptor/myeloid differentiation factor 88-dependent mechanism. J Immunol. 2001 Nov 15; 167(10):5928-34.
    View in: PubMed
    Score: 0.011
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.