"Oncostatin M" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
| Descriptor ID |
D053683
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| MeSH Number(s) |
D12.644.276.374.562 D12.776.467.374.562 D23.529.374.562
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Oncostatin M".
Below are MeSH descriptors whose meaning is more specific than "Oncostatin M".
This graph shows the total number of publications written about "Oncostatin M" by people in this website by year, and whether "Oncostatin M" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Oncostatin M" by people in Profiles.
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Oncostatin M Induces Lipolysis and Suppresses Insulin Response in 3T3-L1 Adipocytes. Int J Mol Sci. 2022 Apr 23; 23(9).
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Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte-Specific Oncostatin Receptor Knockout Mice. Obesity (Silver Spring). 2018 09; 26(9):1439-1447.
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Loss of Oncostatin M Signaling in Adipocytes Induces Insulin Resistance and Adipose Tissue Inflammation in Vivo. J Biol Chem. 2016 08 12; 291(33):17066-76.