"Leukotrienes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of biologically active compounds derived from arachidonic acid by oxidative metabolism through the 5-lipoxygenase pathway. They participate in host defense reactions and pathophysiological conditions such as immediate hypersensitivity and inflammation. They have potent actions on many essential organs and systems, including the cardiovascular, pulmonary, and central nervous system as well as the gastrointestinal tract and the immune system.
| Descriptor ID |
D015289
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| MeSH Number(s) |
D10.251.355.255.100.450 D10.251.355.310.166.887 D23.469.050.175.450
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Leukotrienes".
Below are MeSH descriptors whose meaning is more specific than "Leukotrienes".
This graph shows the total number of publications written about "Leukotrienes" by people in this website by year, and whether "Leukotrienes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
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Below are the most recent publications written about "Leukotrienes" by people in Profiles.
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Leukotriene metabolism by intrapulmonary vessels of newborn lambs: effect of platelet-activating factor. Exp Lung Res. 2001 Jun; 27(4):331-48.
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Leukotriene synthesis by isolated perinatal ovine intrapulmonary vessels correlates with age-related changes in 5-lipoxygenase protein. Biochem Mol Med. 1997 Jun; 61(1):63-71.
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Developmental differences in production of lipoxygenase metabolites by ovine lungs. Exp Lung Res. 1995 May-Jun; 21(3):385-405.
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Plasma and urinary leukotrienes in sickle cell disease: possible role in the inflammatory process. Eur J Clin Invest. 1994 Jan; 24(1):57-64.
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Endogenous arachidonic acid metabolism by calcium ionophore stimulated ferret lungs. Effect of age, hypoxia. Lab Invest. 1992 Mar; 66(3):370-7.
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Metabolism of endogenous arachidonic acid by isolated lungs of neonatal and adult rabbits stimulated with calcium ionophore: effect of hypoxia. Exp Lung Res. 1992 Jan-Mar; 18(1):69-85.
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Endogenous arachidonic acid metabolism by calcium ionophore A23187-stimulated lamb lungs: effect of hypoxia. Am J Respir Cell Mol Biol. 1991 Apr; 4(4):379-85.