"Mifepristone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Descriptor ID |
D015735
|
MeSH Number(s) |
D04.210.500.365.415.580
|
Concept/Terms |
R-38486- R-38486
- R 38486
- RU-486
- RU 486
- RU486
- R38486
- RU-38486
- RU 38486
- RU38486
|
Below are MeSH descriptors whose meaning is more general than "Mifepristone".
Below are MeSH descriptors whose meaning is more specific than "Mifepristone".
This graph shows the total number of publications written about "Mifepristone" by people in this website by year, and whether "Mifepristone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mifepristone" by people in Profiles.
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Increased glycogen synthase kinase-3ß and hexose-6-phosphate dehydrogenase expression in adipose tissue may contribute to glucocorticoid-induced mouse visceral adiposity. Int J Obes (Lond). 2016 08; 40(8):1233-41.
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Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids. 2011 Aug; 76(9):910-20.
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Expression of endometrial glycogen synthase kinase-3beta protein throughout the menstrual cycle and its regulation by progesterone. Mol Hum Reprod. 2006 Sep; 12(9):543-9.
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Increased glucocorticoid receptor and 11{beta}-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in db/db mice. Diabetes. 2005 Jan; 54(1):32-40.
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Glucocorticoid-induced skeletal muscle atrophy is associated with upregulation of myostatin gene expression. Am J Physiol Endocrinol Metab. 2003 Aug; 285(2):E363-71.