"Perilipin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
| Descriptor ID |
D000070780
|
| MeSH Number(s) |
D12.776.157.464.500.750
|
| Concept/Terms |
Perilipin-2- Perilipin-2
- Perilipin 2
- ADRP Protein
- Adipose Differentiation-Related Protein
- Adipose Differentiation Related Protein
- Protein, Adipose Differentiation-Related
- PLIN2 Protein
- Protein, PLIN2
- Perilipin 2 Protein
- Protein, Perilipin 2
- Adipophilin
|
Below are MeSH descriptors whose meaning is more general than "Perilipin-2".
Below are MeSH descriptors whose meaning is more specific than "Perilipin-2".
This graph shows the total number of publications written about "Perilipin-2" by people in this website by year, and whether "Perilipin-2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Perilipin-2" by people in Profiles.
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Neutral lipid trafficking regulates alveolar type II cell surfactant phospholipid and surfactant protein expression. Exp Lung Res. 2011 Aug; 37(6):376-86.
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Evidence for in vivo nicotine-induced alveolar interstitial fibroblast-to-myofibroblast transdifferentiation. Exp Lung Res. 2010 Sep; 36(7):390-8.
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Peroxisome proliferator-activated receptor gamma agonists enhance lung maturation in a neonatal rat model. Pediatr Res. 2009 Feb; 65(2):150-5.
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Reversal of nicotine-induced alveolar lipofibroblast-to-myofibroblast transdifferentiation by stimulants of parathyroid hormone-related protein signaling. Lung. 2007 May-Jun; 185(3):151-9.
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Up-regulation of fetal rat lung parathyroid hormone-related protein gene regulatory network down-regulates the Sonic Hedgehog/Wnt/betacatenin gene regulatory network. Pediatr Res. 2006 Oct; 60(4):382-8.
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Rosiglitazone, a peroxisome proliferator-activated receptor-gamma agonist, prevents hyperoxia-induced neonatal rat lung injury in vivo. Pediatr Pulmonol. 2006 Jun; 41(6):558-69.
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The role of fibroblast transdifferentiation in lung epithelial cell proliferation, differentiation, and repair in vitro. Pediatr Pathol Mol Med. 2003 May-Jun; 22(3):189-207.
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Hyperoxia augments pulmonary lipofibroblast-to-myofibroblast transdifferentiation. Cell Biochem Biophys. 2003; 38(3):239-50.
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Oxygen-induced metabolic changes and transdifferentiation in immature fetal rat lung lipofibroblasts. Mol Genet Metab. 2002 Nov; 77(3):230-6.
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Stretch-stimulated surfactant synthesis is coordinated by the paracrine actions of PTHrP and leptin. Am J Physiol Lung Cell Mol Physiol. 2002 Jul; 283(1):L130-5.