"Pyroglutamyl-Peptidase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.
| Descriptor ID |
D011751
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| MeSH Number(s) |
D08.811.277.656.350.100.755
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| Concept/Terms |
Pyroglutamyl-Peptidase I- Pyroglutamyl-Peptidase I
- Pyroglutamyl Peptidase I
- 5-Oxoprolyl-Peptidase
- 5 Oxoprolyl Peptidase
- Pyrrolidonecarboxylate Peptidase
- Peptidase, Pyrrolidonecarboxylate
- Pyrrolidonyl Peptidase
- Peptidase, Pyrrolidonyl
- Pyroglutamate Aminopeptidase
- Aminopeptidase, Pyroglutamate
- Pyroglutamyl-Peptide Hydrolase
- Pyroglutamyl Peptide Hydrolase
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Below are MeSH descriptors whose meaning is more general than "Pyroglutamyl-Peptidase I".
Below are MeSH descriptors whose meaning is more specific than "Pyroglutamyl-Peptidase I".
This graph shows the total number of publications written about "Pyroglutamyl-Peptidase I" by people in this website by year, and whether "Pyroglutamyl-Peptidase I" was a major or minor topic of these publications.
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Below are the most recent publications written about "Pyroglutamyl-Peptidase I" by people in Profiles.
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Delineation of a particulate thyrotropin-releasing hormone-degrading enzyme in rat brain by the use of specific inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase. J Neurochem. 1986 Apr; 46(4):1231-9.
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The effect of inhibitors of prolyl endopeptidase and pyroglutamyl peptide hydrolase on TRH degradation in rat serum. Biochem Biophys Res Commun. 1985 Oct 30; 132(2):787-94.
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Pyroglutamyl diazomethyl ketone: potent inhibitor of mammalian pyroglutamyl peptide hydrolase. Biochem Biophys Res Commun. 1985 Jul 31; 130(2):662-8.