"Symporters" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane transporters that co-transport two or more dissimilar molecules in the same direction across a membrane. Usually the transport of one ion or molecule is against its electrochemical gradient and is "powered" by the movement of another ion or molecule with its electrochemical gradient.
| Descriptor ID |
D027981
|
| MeSH Number(s) |
D12.776.157.530.450.625 D12.776.543.585.450.625
|
| Concept/Terms |
Symporters- Symporters
- Co-Transporters
- Co Transporters
|
Below are MeSH descriptors whose meaning is more general than "Symporters".
Below are MeSH descriptors whose meaning is more specific than "Symporters".
This graph shows the total number of publications written about "Symporters" by people in this website by year, and whether "Symporters" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Symporters" by people in Profiles.
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A New Twist on a Classic: Enhancing Radioiodine Uptake in Advanced Thyroid Cancer. Clin Cancer Res. 2024 04 01; 30(7):1220-1222.
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Use of sodium-glucose co-transporter-2 inhibitors in patients with and without type 2 diabetes: implications for incident and prevalent heart failure. Eur J Heart Fail. 2020 04; 22(4):604-617.
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Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease. Brain. 2017 12 01; 140(12):3191-3203.
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Vitamin D deficiency promotes nonalcoholic steatohepatitis through impaired enterohepatic circulation in animal model. Am J Physiol Gastrointest Liver Physiol. 2014 Nov 01; 307(9):G883-93.
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Cancer: Novel target to enhance radioiodine uptake in thyroid cancer. Nat Rev Endocrinol. 2013 Sep; 9(9):508-9.
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The sodium iodide symporter (NIS): regulation and approaches to targeting for cancer therapeutics. Pharmacol Ther. 2012 Sep; 135(3):355-70.
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Regulation of sodium iodide symporter gene expression by Rac1/p38? mitogen-activated protein kinase signaling pathway in MCF-7 breast cancer cells. J Biol Chem. 2012 Jan 27; 287(5):3292-300.
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Retinoic acid induces expression of the thyroid hormone transporter, monocarboxylate transporter 8 (Mct8). J Biol Chem. 2010 Aug 27; 285(35):27279-27288.
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Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. Cancer Res. 2009 Apr 15; 69(8):3443-50.
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Phosphoinositide-3-kinase inhibition induces sodium/iodide symporter expression in rat thyroid cells and human papillary thyroid cancer cells. J Endocrinol. 2008 Nov; 199(2):243-52.