Central Nervous System Depressants
"Central Nervous System Depressants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).
Descriptor ID |
D002492
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MeSH Number(s) |
D27.505.696.277 D27.505.954.427.210
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Central Nervous System Depressants".
Below are MeSH descriptors whose meaning is more specific than "Central Nervous System Depressants".
This graph shows the total number of publications written about "Central Nervous System Depressants" by people in this website by year, and whether "Central Nervous System Depressants" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2010 | 0 | 2 | 2 |
2011 | 1 | 1 | 2 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Central Nervous System Depressants" by people in Profiles.
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A Novel and Selective Nociceptin Receptor (NOP) Agonist (1-(1-((cis)-4-isopropylcyclohexyl)piperidin-4-yl)-1H-indol-2-yl)methanol (AT-312) Decreases Acquisition of Ethanol-Induced Conditioned Place Preference in Mice. Alcohol Clin Exp Res. 2018 Feb; 42(2):461-471.
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The role of endogenous dynorphin in ethanol-induced state-dependent CPP. Behav Brain Res. 2012 Feb 01; 227(1):58-63.
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Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcohol Clin Exp Res. 2011 Aug; 35(8):1509-18.
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Effects of ethanol on the proteasome interacting proteins. World J Gastroenterol. 2010 Mar 21; 16(11):1349-57.
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Alcohol, nutrition and liver cancer: role of Toll-like receptor signaling. World J Gastroenterol. 2010 Mar 21; 16(11):1344-8.
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Chronic ethanol feeding alters hepatocyte memory which is not altered by acute feeding. Alcohol Clin Exp Res. 2009 Apr; 33(4):684-92.
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Gene expression patterns of the liver in response to alcohol: in vivo and in vitro models compared. Exp Mol Pathol. 2006 Jun; 80(3):241-51.
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The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal. Exp Mol Pathol. 2005 Apr; 78(2):109-15.