"Choline Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
Descriptor ID |
D002796
|
MeSH Number(s) |
C18.654.521.500.133.699.160
|
Concept/Terms |
Choline Deficiency- Choline Deficiency
- Deficiency, Choline
- Choline Deficiencies
- Deficiencies, Choline
|
Below are MeSH descriptors whose meaning is more general than "Choline Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Choline Deficiency".
This graph shows the total number of publications written about "Choline Deficiency" by people in this website by year, and whether "Choline Deficiency" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 0 | 1 | 1 |
2010 | 0 | 2 | 2 |
2013 | 0 | 1 | 1 |
2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Choline Deficiency" by people in Profiles.
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Inhibition of hyaluronan synthesis by 4-methylumbelliferone ameliorates non-alcoholic steatohepatitis in choline-deficient L-amino acid-defined diet-induced murine model. Arch Pharm Res. 2021 Feb; 44(2):230-240.
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Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice. Hepatology. 2014 Feb; 59(2):483-95.
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Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Hepatology. 2010 Oct; 52(4):1420-30.
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Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 2010 Jul; 139(1):323-34.e7.
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c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 2009 Oct; 137(4):1467-1477.e5.