Pituitary Adenylate Cyclase-Activating Polypeptide
"Pituitary Adenylate Cyclase-Activating Polypeptide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multi-function neuropeptide that acts throughout the body by elevating intracellular cyclic AMP level via its interaction with PACAP RECEPTORS. Although first isolated from hypothalamic extracts and named for its action on the pituitary, it is widely distributed in the central and peripheral nervous systems. PACAP is important in the control of endocrine and homeostatic processes, such as secretion of pituitary and gut hormones and food intake.
Descriptor ID |
D051219
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MeSH Number(s) |
D12.644.276.860.887 D12.644.400.625 D12.776.467.860.887 D12.776.631.600.887 D12.776.631.650.625 D23.529.850.887
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pituitary Adenylate Cyclase-Activating Polypeptide".
Below are MeSH descriptors whose meaning is more specific than "Pituitary Adenylate Cyclase-Activating Polypeptide".
This graph shows the total number of publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in this website by year, and whether "Pituitary Adenylate Cyclase-Activating Polypeptide" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2009 | 1 | 0 | 1 |
2019 | 2 | 0 | 2 |
2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Pituitary Adenylate Cyclase-Activating Polypeptide" by people in Profiles.
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The role of pituitary adenylyl cyclase activating polypeptide in affective signs of nicotine withdrawal. J Neurosci Res. 2020 08; 98(8):1549-1560.
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The role of pituitary adenylyl cyclase-activating polypeptide in the motivational effects of addictive drugs. Neuropharmacology. 2020 07; 171:108109.
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Emerging evidence for the role of pituitary adenylate cyclase-activating peptide in neuropsychiatric disorders. Prog Mol Biol Transl Sci. 2019; 167:143-157.
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The role of endogenous pituitary adenylyl cyclase activating polypeptide (PACAP) in nicotine self-administration, reward and aversion. Pharmacol Biochem Behav. 2019 06; 181:46-52.
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The role of endogenous PACAP in motor stimulation and conditioned place preference induced by morphine in mice. Psychopharmacology (Berl). 2009 Jun; 204(3):457-63.