"Mice, SCID" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.
Descriptor ID |
D016513
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MeSH Number(s) |
B01.050.150.900.649.313.992.635.505.500.550.780
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Concept/Terms |
Mice, SCID- Mice, SCID
- Severe Combined Immunodeficient Mice
- SCID Mice
- Immunodeficient Mice, Severe Combined
- Mouse, SCID
- SCID Mouse
Mouse, SCID-hu- Mouse, SCID-hu
- Mouse, SCID hu
- SCID-hu Mouse
- SCID-hu Mice
- Mice, SCID-hu
- SCID hu Mice
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Below are MeSH descriptors whose meaning is more general than "Mice, SCID".
Below are MeSH descriptors whose meaning is more specific than "Mice, SCID".
This graph shows the total number of publications written about "Mice, SCID" by people in this website by year, and whether "Mice, SCID" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2011 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mice, SCID" by people in Profiles.
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EMP2 is a novel therapeutic target for endometrial cancer stem cells. Oncogene. 2017 10 19; 36(42):5793-5807.
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Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy. J Exp Clin Cancer Res. 2016 May 06; 35:73.
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Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea. J Nutr Biochem. 2014 Jan; 25(1):73-80.
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Progesterone and estrogen receptor expression and activity in human non-small cell lung cancer. Steroids. 2011 Aug; 76(9):910-20.