"B7-2 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand glycoprotein that contains a C2 and V-type IMMUNOGLOBULIN DOMAIN. It is expressed by ANTIGEN-PRESENTING CELLS and binds to CD28 ANTIGEN with high specificity and to CTLA-4 ANTIGEN with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
Descriptor ID |
D051940
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MeSH Number(s) |
D12.776.467.150.200 D12.776.543.095.200 D23.050.301.285.200 D23.529.168.200
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Concept/Terms |
B7-2 Antigen- B7-2 Antigen
- B7 2 Antigen
- B7-2 Costimulatory Molecule
- Costimulatory Molecule, B7-2
- B70 Costimulatory Molecule
- Costimulatory Molecule, B70
- Early T Cell Costimulatory Molecule 1
- CD86 Antigens
- Antigen, B7-2
- Antigen, B7 2
- Antigens, CD86
- CD86 Antigen
- Antigen, CD86
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Below are MeSH descriptors whose meaning is more general than "B7-2 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-2 Antigen".
This graph shows the total number of publications written about "B7-2 Antigen" by people in this website by year, and whether "B7-2 Antigen" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "B7-2 Antigen" by people in Profiles.
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Marina crystal minerals (MCM) activate human dendritic cells to induce CD4+ and CD8+ T cell responses in vitro. Int J Immunopathol Pharmacol. 2018 Jan-Dec; 32:2058738418797768.
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Activation of human monocyte-derived dendritic cells in vitro by the biological response modifier arabinoxylan rice bran (MGN-3/Biobran). Int J Immunopathol Pharmacol. 2011 Oct-Dec; 24(4):941-8.
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Expression of surface antigens during the differentiation of human dendritic cells vs macrophages from blood monocytes in vitro. Immunobiology. 1999 Jun; 200(2):187-204.