"Apoptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
| Descriptor ID |
D017209
|
| MeSH Number(s) |
G04.146.160
|
| Concept/Terms |
Apoptosis- Apoptosis
- Programmed Cell Death, Type I
|
Below are MeSH descriptors whose meaning is more general than "Apoptosis".
Below are MeSH descriptors whose meaning is more specific than "Apoptosis".
This graph shows the total number of publications written about "Apoptosis" by people in this website by year, and whether "Apoptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2001 | 2 | 4 | 6 |
| 2002 | 2 | 1 | 3 |
| 2003 | 4 | 1 | 5 |
| 2004 | 1 | 3 | 4 |
| 2005 | 5 | 0 | 5 |
| 2006 | 3 | 3 | 6 |
| 2007 | 1 | 2 | 3 |
| 2008 | 5 | 3 | 8 |
| 2009 | 3 | 3 | 6 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 5 | 6 |
| 2014 | 6 | 3 | 9 |
| 2015 | 1 | 1 | 2 |
| 2016 | 6 | 2 | 8 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 4 | 4 |
| 2020 | 2 | 3 | 5 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 3 | 3 |
| 2024 | 1 | 1 | 2 |
| 2025 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Apoptosis" by people in Profiles.
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Protective Effect of Biobran/MGN-3, an Arabinoxylan from Rice Bran, Against the Cytotoxic Effects of Polyethylene Nanoplastics in Normal Mouse Hepatocytes: An In Vitro and In Silico Study. Nutrients. 2025 Jun 13; 17(12).
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Manuka Honey Inhibits Human Breast Cancer Progression in Preclinical Models. Nutrients. 2024 Jul 22; 16(14).
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Targeting the long non-coding RNA MIAT for the treatment of fibroids in an animal model. Clin Sci (Lond). 2024 Jun 19; 138(12):699-709.
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Phytochemicals in Inhibition of Prostate Cancer: Evidence from Molecular Mechanisms Studies. Biomolecules. 2022 09 16; 12(9).
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The role of sphingolipids in meibomian gland dysfunction and ocular surface inflammation. Ocul Surf. 2022 10; 26:100-110.
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Magnesium sulphate neuroprotection mechanism is placental mediated by inhibition of inflammation, apoptosis and oxidative stress. Placenta. 2022 09; 127:29-36.
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Protective Effect of Biobran/MGN-3 against Sporadic Alzheimer's Disease Mouse Model: Possible Role of Oxidative Stress and Apoptotic Pathways. Oxid Med Cell Longev. 2021; 2021:8845064.
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Maternal N-acetyl-cysteine prevents neonatal brain injury associated with necrotizing enterocolitis in a rat model. Acta Obstet Gynecol Scand. 2021 05; 100(5):979-987.
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Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts. Exp Mol Pathol. 2021 02; 118:104573.
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Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):220-233.