"Sirtuin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in the CELL NUCLEUS. It is an NAD-dependent deacetylase with specificity towards HISTONES and a variety of proteins involved in gene regulation.
Descriptor ID |
D056564
|
MeSH Number(s) |
D08.811.277.087.520.200.650.100 D12.776.476.900.100
|
Concept/Terms |
Sirtuin 1- Sirtuin 1
- Silent Mating Type Information Regulation 2 Homolog 1
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 1".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 1".
This graph shows the total number of publications written about "Sirtuin 1" by people in this website by year, and whether "Sirtuin 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2008 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2014 | 1 | 1 | 2 |
2016 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sirtuin 1" by people in Profiles.
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Fetal e-cigarette exposure programs a neonatal brain hypoxic-ischemic sensitive phenotype via altering DNA methylation patterns and autophagy signaling pathway. Am J Physiol Regul Integr Comp Physiol. 2021 11 01; 321(5):R791-R801.
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Ga12 ablation exacerbates liver steatosis and obesity by suppressing USP22/SIRT1-regulated mitochondrial respiration. J Clin Invest. 2018 12 03; 128(12):5587-5602.
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Nicotine plus a high-fat diet triggers cardiomyocyte apoptosis. Cell Tissue Res. 2017 04; 368(1):159-170.
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Programmed hyperphagia secondary to increased hypothalamic SIRT1. Brain Res. 2014 Nov 17; 1589:26-36.
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Developmental programming of appetite/satiety. Ann Nutr Metab. 2014; 64 Suppl 1:36-44.
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Nutrient sensor-mediated programmed nonalcoholic fatty liver disease in low birthweight offspring. Am J Obstet Gynecol. 2012 Oct; 207(4):308.e1-6.
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Sirt1 is involved in energy metabolism: the role of chronic ethanol feeding and resveratrol. Exp Mol Pathol. 2008 Dec; 85(3):155-9.