"Arginase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ureahydrolase that catalyzes the hydrolysis of arginine or canavanine to yield L-ornithine (ORNITHINE) and urea. Deficiency of this enzyme causes HYPERARGININEMIA. EC 3.5.3.1.
| Descriptor ID |
D001119
|
| MeSH Number(s) |
D08.811.277.913.292
|
| Concept/Terms |
Arginase- Arginase
- Liver Immunoregulatory Protein
- Immunoregulatory Protein, Liver
- Protein, Liver Immunoregulatory
- Liver-Derived Inhibitory Protein
- Inhibitory Protein, Liver-Derived
- Liver Derived Inhibitory Protein
- Protein, Liver-Derived Inhibitory
- Hepatic Proliferation Inhibitor
- Inhibitor, Hepatic Proliferation
- Proliferation Inhibitor, Hepatic
|
Below are MeSH descriptors whose meaning is more general than "Arginase".
Below are MeSH descriptors whose meaning is more specific than "Arginase".
This graph shows the total number of publications written about "Arginase" by people in this website by year, and whether "Arginase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Arginase" by people in Profiles.
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Proteomic identification of mitochondrial targets of arginase in human breast cancer. PLoS One. 2013; 8(11):e79242.
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Activation of caspase-3 activity and apoptosis in MDA-MB-468 cells by N(omega)-hydroxy-L-arginine, an inhibitor of arginase, is not solely dependent on reduction in intracellular polyamines. Carcinogenesis. 2001 Nov; 22(11):1863-9.
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Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells. Cancer Res. 2000 Jun 15; 60(12):3305-12.
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Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production. Am J Physiol. 1996 Nov; 271(5 Pt 2):H1988-98.