"Naloxone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific opiate antagonist that has no agonist activity. It is a competitive antagonist at mu, delta, and kappa opioid receptors.
Descriptor ID |
D009270
|
MeSH Number(s) |
D03.132.577.249.706 D03.605.497.750 D03.633.400.686.750 D04.615.723.795.706
|
Concept/Terms |
MRZ-2593- MRZ-2593
- MRZ 2593
- MRZ2593
- MRZ 2593-Br
- MRZ 2593 Br
- MRZ 2593Br
|
Below are MeSH descriptors whose meaning is more general than "Naloxone".
Below are MeSH descriptors whose meaning is more specific than "Naloxone".
This graph shows the total number of publications written about "Naloxone" by people in this website by year, and whether "Naloxone" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2013 | 0 | 1 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Naloxone" by people in Profiles.
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Prohormone convertase 2 (PC2) null mice have increased mu opioid receptor levels accompanied by altered morphine-induced antinociception, tolerance and dependence. Neuroscience. 2016 08 04; 329:318-25.
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The role of endogenous beta-endorphin and enkephalins in ethanol reward. Neuropharmacology. 2013 Oct; 73:290-300.
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Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration. Eur J Pharmacol. 2011 Jan 15; 650(2-3):563-7.
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Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test. Br J Pharmacol. 2000 Dec; 131(8):1684-8.
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Differential sensitivity of mice bred for stress-induced analgesia to morphine and ACEA-1011 in the formalin test. Pharmacol Biochem Behav. 1996 Jun; 54(2):495-500.
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Blockade of morphine-induced analgesia and tolerance in mice by MK-801. Brain Res. 1993 Jul 09; 616(1-2):83-8.
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Simultaneous development of opioid tolerance and opioid antagonist-induced receptor upregulation. Brain Res. 1990 Oct 08; 529(1-2):143-8.
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Tolerance develops to spinal morphine analgesia but not morphine-induced convulsions. Eur J Pharmacol. 1990 Jan 25; 176(1):63-7.
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In vitro d-amphetamine and cocaine increase opioid binding in mouse brain homogenate. NIDA Res Monogr. 1990; 105:522-3.
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Role of opioid peptides in pulsatile release of gonadotropins and prolactin in the rat. Brain Res Bull. 1987 Nov; 19(5):539-44.