"Synaptic Transmission" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.
| Descriptor ID |
D009435
|
| MeSH Number(s) |
G02.111.820.850 G04.835.850 G07.265.880 G11.561.830
|
| Concept/Terms |
Synaptic Transmission- Synaptic Transmission
- Neural Transmission
- Neurotransmission
- Transmission, Neural
- Transmission, Synaptic
|
Below are MeSH descriptors whose meaning is more general than "Synaptic Transmission".
Below are MeSH descriptors whose meaning is more specific than "Synaptic Transmission".
This graph shows the total number of publications written about "Synaptic Transmission" by people in this website by year, and whether "Synaptic Transmission" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptic Transmission" by people in Profiles.
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Overcoming presynaptic effects of VAMP2 mutations with 4-aminopyridine treatment. Hum Mutat. 2020 11; 41(11):1999-2011.
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Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain. Elife. 2020 04 14; 9.
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Opioids modulate an emergent rhythmogenic process to depress breathing. Elife. 2019 12 16; 8.
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cindr, the Drosophila Homolog of the CD2AP Alzheimer's Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis. Cell Rep. 2019 08 13; 28(7):1799-1813.e5.
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Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain. Brain Struct Funct. 2016 Mar; 221(2):923-40.
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Efficient measurement of endogenous neurotransmitters in small localized regions of central nervous systems in vitro with HPLC. J Neurosci Methods. 2007 Mar 15; 160(2):256-63.