"Receptors, LDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Receptors on the plasma membrane of nonhepatic cells that specifically bind LDL. The receptors are localized in specialized regions called coated pits. Hypercholesteremia is caused by an allelic genetic defect of three types: 1, receptors do not bind to LDL; 2, there is reduced binding of LDL; and 3, there is normal binding but no internalization of LDL. In consequence, entry of cholesterol esters into the cell is impaired and the intracellular feedback by cholesterol on 3-hydroxy-3-methylglutaryl CoA reductase is lacking.
| Descriptor ID |
D011973
|
| MeSH Number(s) |
D12.776.543.750.710.450
|
| Concept/Terms |
Receptors, LDL- Receptors, LDL
- LDL Receptors
- LDL Receptors, Lipoprotein
- Receptors, Lipoprotein LDL
- Lipoprotein LDL Receptors
- Low Density Lipoprotein Receptors
- Receptors, Lipoprotein, LDL
- Receptors, Low Density Lipoprotein
- LDL Receptor
- Receptor, LDL
- Low Density Lipoprotein Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, LDL".
Below are MeSH descriptors whose meaning is more specific than "Receptors, LDL".
This graph shows the total number of publications written about "Receptors, LDL" by people in this website by year, and whether "Receptors, LDL" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
| 2026 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Receptors, LDL" by people in Profiles.
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Follistatin Mitigates Atherosclerosis Through Activation of Arginine Metabolism and Adipose Browning. Cells. 2026 Jul 02; 15(13).
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Cardiovascular-specific PTH1R activation enhances exercise-induced cardiac remodeling in a mouse model of calcific atherosclerosis. Biochem Biophys Res Commun. 2026 Jul 09; 821:153870.
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Trimethylamine-N-Oxide Affects Cell Type-Specific Pathways and Networks in Mouse Aorta to Promote Atherosclerotic Plaque Vulnerability. Arterioscler Thromb Vasc Biol. 2025 10; 45(10):1784-1798.
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Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):220-233.
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Heterozygous osteopetrotic (op) mutation reduces atherosclerosis in LDL receptor- deficient mice. J Clin Invest. 1998 Jun 15; 101(12):2702-10.
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Low density lipoprotein receptors mediate intracellular calcium signals in microalbuminuric hypertensives. Am J Hypertens. 1998 Jan; 11(1 Pt 1):113-6.
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Identification of a zinc finger protein that binds to the sterol regulatory element. Science. 1989 Aug 11; 245(4918):640-3.