Structure-Activity Relationship
"Structure-Activity Relationship" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
| Descriptor ID |
D013329
|
| MeSH Number(s) |
G02.111.830 G07.690.773.997
|
| Concept/Terms |
Structure-Activity Relationship- Structure-Activity Relationship
- Relationship, Structure-Activity
- Relationships, Structure-Activity
- Structure Activity Relationship
- Structure-Activity Relationships
|
Below are MeSH descriptors whose meaning is more general than "Structure-Activity Relationship".
Below are MeSH descriptors whose meaning is more specific than "Structure-Activity Relationship".
This graph shows the total number of publications written about "Structure-Activity Relationship" by people in this website by year, and whether "Structure-Activity Relationship" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Structure-Activity Relationship" by people in Profiles.
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Strong functional data for pathogenicity or neutrality classify BRCA2 DNA-binding-domain variants of uncertain significance. Am J Hum Genet. 2021 03 04; 108(3):458-468.
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Flavonoid compounds isolated from Tibetan herbs, binding to GABAA receptor with anxiolytic property. J Ethnopharmacol. 2021 Mar 01; 267:113630.
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Author Response: Comparison of Local Structure-Function Relationships and Dynamic Range in Glaucoma. Invest Ophthalmol Vis Sci. 2016 11 01; 57(14):6406.
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Clinical outcomes with active versus nutritional vitamin D compounds in chronic kidney disease. Clin J Am Soc Nephrol. 2009 Sep; 4(9):1529-39.
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Platelet-activating factor stimulates ovine foetal pulmonary vascular smooth muscle cell proliferation: role of nuclear factor-kappa B and cyclin-dependent kinases. Cell Prolif. 2008 Apr; 41(2):208-29.
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Iloperidone: a new benzisoxazole atypical antipsychotic drug. Is it novel enough to impact the crowded atypical antipsychotic market? Expert Opin Investig Drugs. 2008 Jan; 17(1):61-75.
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Clarithromycin-induced ventricular tachycardia. Ann Emerg Med. 1997 Oct; 30(4):542-4.
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Vascular effects of platelet-activating factor in lambs: role of cyclo- and lipoxygenase. J Appl Physiol (1985). 1992 Dec; 73(6):2559-66.
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Synthesis and transport applications of 3-aminobicyclo[3.2.1] octane-3-carboxylic acids. J Med Chem. 1983 Oct; 26(10):1374-8.
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Comparative effect of a family of substituted thiopseudoureas on protein synthesis by rat liver and Walker carcinoma ribosomes. Chem Biol Interact. 1978 Sep; 22(2-3):309-27.