Mitogen-Activated Protein Kinases
"Mitogen-Activated Protein Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superfamily of PROTEIN-SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).
Descriptor ID |
D020928
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MeSH Number(s) |
D08.811.913.696.620.682.700.567 D12.644.360.450 D12.776.476.450
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Concept/Terms |
Mitogen-Activated Protein Kinases- Mitogen-Activated Protein Kinases
- Kinases, Mitogen-Activated Protein
- Mitogen Activated Protein Kinases
- Protein Kinases, Mitogen-Activated
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Below are MeSH descriptors whose meaning is more general than "Mitogen-Activated Protein Kinases".
Below are MeSH descriptors whose meaning is more specific than "Mitogen-Activated Protein Kinases".
This graph shows the total number of publications written about "Mitogen-Activated Protein Kinases" by people in this website by year, and whether "Mitogen-Activated Protein Kinases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 1 | 1 | 2 |
2006 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitogen-Activated Protein Kinases" by people in Profiles.
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MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis. Breast Cancer Res Treat. 2018 Aug; 170(3):477-486.
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Maternal undernourished fetal kidneys exhibit differential regulation of nephrogenic genes including downregulation of the Notch signaling pathway. Reprod Sci. 2011 Jun; 18(6):563-76.
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Mitogen-activated protein kinase signaling in male germ cell apoptosis in the rat. Biol Reprod. 2009 Apr; 80(4):771-80.
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Insulin-like growth factor I differentially regulates the expression of HIRF1/hCAF1 and BTG1 genes in human MCF-7 breast cancer cells. Int J Mol Med. 2006 Jul; 18(1):129-39.
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MKP-1-induced dephosphorylation of extracellular signal-regulated kinase is essential for triggering nitric oxide-induced apoptosis in human breast cancer cell lines: implications in breast cancer. Cancer Res. 2003 Dec 15; 63(24):8853-60.
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Buprenorphine-induced antinociception is mediated by mu-opioid receptors and compromised by concomitant activation of opioid receptor-like receptors. J Neurosci. 2003 Nov 12; 23(32):10331-7.
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Squalamine and cisplatin block angiogenesis and growth of human ovarian cancer cells with or without HER-2 gene overexpression. Oncogene. 2002 Apr 25; 21(18):2805-14.
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Membrane-associated binding sites for estrogen contribute to growth regulation of human breast cancer cells. Oncogene. 2001 Sep 06; 20(39):5420-30.